Browse our MYL2 (MYL2) ELISA Kits

Full name:
Myosin, Light Chain 2, Regulatory, Cardiac, Slow ELISA Kits (MYL2)
On www.antibodies-online.com are 5 Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) ELISA Kits from 4 different suppliers available. Additionally we are shipping MYL2 Antibodies (106) and MYL2 Proteins (16) and many more products for this protein. A total of 132 MYL2 products are currently listed.
Synonyms:
2410014J02Rik, CMH10, Mlc-2, MLC-2v, MLC2, Mlc2v, Mylpc, myosin, regulatory
list all ELISA KIts Gene Name GeneID UniProt
MYL2 17907 P97457
MYL2 4633 P10916
Rat MYL2 MYL2 363925 P08733

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MYL2 (MYL2) ELISA Kits by Reactivity

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Mouse (Murine) Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. transgenic mouse models of hypertrophic cardiomyopathy may be caused by mutations in myosin regulatory light chain

  2. MLC2 phosphorylation regulates actin-based cytokinesis in mouse oocytes, and this regulation may be mediated via a RhoA-MLC2-actin pathway.

  3. Treatment of mice with an AT1R (show AGTRAP ELISA Kits) biased ligand, acting via beta-arrestin signalling, is able to induce an increase in cardiac contractility associated with an increase in ventricular myosin light chain-2 (show MYL12B ELISA Kits) phosphorylation

  4. Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.

  5. Mammalian target of rapamycin (mTOR (show FRAP1 ELISA Kits)) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein (show TNNT2 ELISA Kits) expression.

  6. Data indicate that NRG-1beta up-regulated the gene expressions of Nkx2.5 (show NKX2-5 ELISA Kits), GATA4 (show GATA4 ELISA Kits), alpha-actin (show ACTA2 ELISA Kits), MLC-2v, and ANF (show HESX1 ELISA Kits) in a time-dependent regulation of ErbB (show EGFR ELISA Kits)/ERK1/2 (show MAPK1/3 ELISA Kits) pathways.

  7. Results indicated that sine oculis homeobox (show PRRX1 ELISA Kits) 1 (Six1 (show SIX1 ELISA Kits)) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 ELISA Kits), Srl (show SRL ELISA Kits), and Mylpf (show MYLPF ELISA Kits).

  8. High resolution characterization of myosin IIC protein tailpiece and its effect on filament assembly

  9. Accelerated cMLCK protein turnover by the ubiquitin-proteasome system underlies the transition from compensated hypertrophy to decompensated heart failure as a result of reduced phosphorylation of MLC2v.

  10. Results show that the binding force between selenium and cardiac myosin (CM), which consists of two heavy chains (MHC) and two pairs of light chains: MLC1 and MLC2, was 100 times stronger than that of daunorubicin (DNR) and CM.

Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. This exome-wide association study indicated that C12orf51 rs11066280, MYL2 rs12229654, and ALDH2 (show ALDH2 ELISA Kits) rs671 polymorphisms are linked to blood Pb levels in the Korean population.

  2. differential regulation of PKA and cell stiffness in unconfined versus confined cells is abrogated by dual, but not individual, inhibition of Piezo1 and myosin II.

  3. Mutation in myosin regulatory light chain gene is associated with defective myosin motor function that ultimately result in pathological hypertrophic remodeling.

  4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2 (show MYL12B ELISA Kits)) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1 (show PPP1R12A ELISA Kits)) localized to the bicellular regions.

  5. Structural dynamics-based approach reveals that the E56G mutation in human ventricular essential light chain affects the structure of the actin-myosin complex in the presence of ATP. The mutation increases the population in the S structural state (increasing the duty ratio), and changes the structure of the W state, so that it more closely resembles the S state.

  6. Two siblings with hypertrophic cardiomyopathy had the pathogenic variant p.Ala13Thr variant in MYL2.

  7. the MYL2 gene on chromosome 12 is associated with serum HDL (show HSD11B1 ELISA Kits)-C levels in Korean men. The association was much stronger in male obese subjects and smokers than that in leaner (show CACNA1A ELISA Kits) nonsmoking male subjects.

  8. FLNb (show FLNB ELISA Kits) enhances invasion of cancer cells through phosphorylation of MRLC and FAK (show PTK2 ELISA Kits).

  9. Ostf1b could constitutively activate the Rho kinase (show ROCK1 ELISA Kits) 1 (ROCK1 (show ROCK1 ELISA Kits)) and myosin light chain 2 (MLC2 (show MYL12B ELISA Kits)) signalling pathway that promotes cell migration, epithelial mesenchymal transition (EMT (show ITK ELISA Kits)) and cytoskeletal dynamics through stress fibre formation.

  10. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

MYL2 Antigen Profile

Antigen Summary

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Alternative names and synonyms associated with MYL2

  • myosin light chain, phosphorylatable, fast skeletal muscle (Mylpf) Elisa Kit
  • Myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like (LOC100353304) Elisa Kit
  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) Elisa Kit
  • myosin, light chain 2, regulatory, cardiac, slow (Myl2) Elisa Kit
  • myosin, light chain 9, regulatory (MYL9) Elisa Kit
  • myosin, light polypeptide 2, regulatory, cardiac, slow (Myl2) Elisa Kit
  • 2410014J02Rik Elisa Kit
  • CMH10 Elisa Kit
  • Mlc-2 Elisa Kit
  • MLC-2v Elisa Kit
  • MLC2 Elisa Kit
  • Mlc2v Elisa Kit
  • Mylpc Elisa Kit
  • myosin Elisa Kit
  • regulatory Elisa Kit

Protein level used designations for MYL2

MLC2F , fast skeletal myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, skeletal muscle isoform , MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , cardiac myosin light chain-2 , DTNB , G1 , isoform L20-A , light polypeptide 9 , myosin regulatory light chain 2, smooth muscle major isoform , myosin regulatory light polypeptide 9 , myosin, light polypeptide 9, regulatory , smooth muscle major isoform , myosin light chain 2v , myosin light chain, phosphorylatable, cardiac ventricles , ventricular myosin regulatory light chain

GENE ID SPECIES
17907 Mus musculus
100353304 Oryctolagus cuniculus
4633 Homo sapiens
363925 Rattus norvegicus
505519 Bos taurus
396215 Gallus gallus
17906 Mus musculus
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