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OXT was up-regulated in both hypothalamic magnocellular neurosecretory cells and parvocellular cells by chronic inflammation, and also that OXT in the PVN-spinal pathway may be involved in sensory modulation
Oxtr (show OXTR Proteins) signaling is crucial for entrainment of odor to social cues but is dispensable for entrainment to nonsocial cues. Oxt conveys saliency of social stimuli to sensory representations in the piriform cortex during odor-driven social learning.
Nos1 (show NOS1 Proteins) neurons of paraventricular nucleus of the hypothalamus promote negative energy balance through changes in feeding and energy expenditure, whereas OXT neurons regulate energy expenditure alone.
Data suggest that oxytocin plays a crucial role in the sexual behavior display, number of released oocytes and density of dendritic spines in the MePD (show THOP1 Proteins) of female mice without affecting AVP (show AVP Proteins) plasma concentration
lactic acid microbes accelerate wound healing via the neuropeptide hormone oxytocin
CD38 in the nucleus accumbens and oxytocin are critical in paternal behavior.
the rewarding properties of social interaction in mice require the coordinated activity of oxytocin and 5-HT (show DDC Proteins) in the nucleus accumbens--with implications for understanding the pathogenesis of social dysfunction in neuropsychiatric disorders like autism
medial amygdala likely modulates hostile aggressive behavior associated with immediate early (show JUN Proteins) gene expression in OXT and vasopressin (show AVP Proteins) neurons
these results support the hypothesis that the expression of the mouse oxytocin receptor (show OXTR Proteins) gene is epigenetically regulated by DNA methylation (show HELLS Proteins) of its promoter.
We conclude that Maged1 (show MAGED1 Proteins) is required for oxytocin processing or stability. A decrease in mature OT levels in Maged1 (show MAGED1 Proteins) mutants affects social interactions and possibly other behavioral processes
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Neurophysin 1 specifically binds oxytocin.
, oxytocin-neurophysin 1