Browse our RGS17 Proteins (RGS17)

Full name:
Regulator of G-Protein Signaling 17 Proteins (RGS17)
On are 8 Regulator of G-Protein Signaling 17 (RGS17) Proteins from 5 different suppliers available. Additionally we are shipping RGS17 Antibodies (35) and many more products for this protein. A total of 48 RGS17 products are currently listed.
6430507P11Rik, hRGS17, MGC179306, RGS-17, RGS17, Rgsz2, zgc:92802
list all proteins Gene Name GeneID UniProt
Rat RGS17 RGS17 308118  
RGS17 26575 Q9UGC6
RGS17 56533 Q9QZB0

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RGS17 Proteins (RGS17) by Origin

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Top referenced RGS17 Proteins

  1. Human RGS17 Protein expressed in Escherichia coli (E. coli) - ABIN667548 : Mao, Zhao, Daigle, Ghahremani, Chidiac, Albert: RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for 667548

More Proteins for RGS17 Interaction Partners

Human Regulator of G-Protein Signaling 17 (RGS17) interaction partners

  1. Variation in RGS17 was associated with risk for substance dependence diagnoses in both African American and European American populations.

  2. Two single nucleotide polymorphisms in the regulator of G-protein signaling 17 gene are associated with smoking initiation.

  3. RGS17 is differentially expressed in hepatocellular carcinoma cells and plays a central role in regulating transformed hepatocyte tumorgenicity.

  4. Results establish RGS10 (show RGS10 Proteins) and RGS17 as novel regulators of cell survival and chemoresistance in ovarian cancer cells and suggest that their reduced expression may be diagnostic of chemoresistance.

  5. Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.

  6. RGS17 is a new RZ member that preferentially inhibits receptor signaling via G(i/o), G(z), and G(q) over G(s) to enhance cAMP-dependent signaling and inhibit calcium signaling

  7. RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP (show APRT Proteins)-PKA-CREB (show CREB1 Proteins) pathway.

  8. RGS17 is a major candidate for the familial lung cancer susceptibility locus on chromosome 6q23-25.

Mouse (Murine) Regulator of G-Protein Signaling 17 (RGS17) interaction partners

  1. SUMO-SIM (show STIM1 Proteins) interactions regulate the activity of RGSZ2 proteins

  2. This RGSZ2-dependent regulation of NMDAR (show GRIN1 Proteins) activity is relevant to persistent pain disorders associated with heightened NMDAR (show GRIN1 Proteins)-mediated glutamate (show GRIN1 Proteins) responses and the reduced antinociceptive capacity of opioids.

  3. These results indicate that the NMDAR (show GRIN1 Proteins)/nNOS (show NOS1 Proteins) cascade, activated via MORs, provide the free zinc ions required for inactive PKCgamma (show PRKCG Proteins) to bind to HINT1 (show HINT1 Proteins)/RGSZ complex at the C terminus of the receptor.

RGS17 Protein Profile

Protein Summary

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Alternative names and synonyms associated with RGS17

  • regulator of G-protein signaling 17 (RGS17)
  • regulator of G-protein signaling 17 (Rgs17)
  • regulator of G-protein signaling 17 (rgs17)
  • 6430507P11Rik protein
  • hRGS17 protein
  • MGC179306 protein
  • RGS-17 protein
  • RGS17 protein
  • Rgsz2 protein
  • zgc:92802 protein

Protein level used designations for RGS17

regulator of G-protein signalling 17 , regulator of G-protein signaling 17 , regulator of G-protein signaling Z2 , regulator of Gz-selective protein signaling 2 , RGS protein RGS-17

608867 Canis lupus familiaris
737204 Pan troglodytes
308118 Rattus norvegicus
436796 Danio rerio
504255 Bos taurus
26575 Homo sapiens
56533 Mus musculus
395645 Gallus gallus
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