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Full name:
Regulator of G-Protein Signaling 6 ELISA Kits (RGS6)
On www.antibodies-online.com are 5 Regulator of G-Protein Signaling 6 (RGS6) ELISA Kits from 4 different suppliers available. Additionally we are shipping RGS6 Antibodies (29) and RGS6 Proteins (6) and many more products for this protein. A total of 45 RGS6 products are currently listed.
Synonyms:
DKFZp459O0734, GAP, hm:zeh0300, RGS6, si:ch211-268e23.2
list all ELISA KIts Gene Name GeneID UniProt
Human RGS6 RGS6 9628 P49758
Mouse RGS6 RGS6 50779 Q9Z2H2
RGS6 54295  

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Human Regulator of G-Protein Signaling 6 (RGS6) interaction partners

  1. Data support the notion that the Galpha (show SUCLG1 ELISA Kits), but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 (show TRPC4 ELISA Kits) activation and unveil new roles for RGS (show PITX2 ELISA Kits) and RGS6 in fine-tuning TRPC4 (show TRPC4 ELISA Kits) activities.

  2. No significant association between SNPs of RGS6 and central adiposity has been found.

  3. reduced RGS6 expression is associated with poor survival in colorectal cancer patients, suggesting that RGS6 expression may serve as an important prognostic marker

  4. these date demonstrate that RGS6 decreases in tumor tissue and may serve as a novel biomarker for outcomes in pancreatic cancer patients and be a potential therapeutic target potential therapeutic target.

  5. we found a novel mutation in RGS6, the splice-acceptor variant c.1369-1G>C that was not previously reported in congenital cataract phenotypes.

  6. genetic association studies in Hispanic-American families in Texas and Colorado: SNP in RGS6 are associated with high dietary fat intake, food preferences, and adiposity/obesity phenotype

  7. RGS6-induced apoptosis in both breast cancer cells and mouse embryonic fibroblasts does not require its GAP activity toward G proteins

  8. interacts with SCG10 (show STMN2 ELISA Kits) and promotes neuronal differentiation; role of the G gamma subunit-like (GGL (show GGT5 ELISA Kits)) domain of this protein

  9. Role of the RGS (show PITX2 ELISA Kits) domain in stress-induced trafficking of RGS6 protein

  10. RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL (show GGT5 ELISA Kits)) domain in subcellular localization of RGS6 splice variants

Mouse (Murine) Regulator of G-Protein Signaling 6 (RGS6) interaction partners

  1. The genetic loss of Rgs6 is associated with three phenotypes each individually associated with midbrain dopaminergic neuron neuron degeneration.

  2. propose that inhibition of RGS6 might represent a viable means to reduce alcohol cravings and withdrawal in human patients, while simultaneously protecting the heart and liver from further damage upon relapse

  3. RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60 (show KAT5 ELISA Kits)-mediated Dnmt1 (show DNMT1 ELISA Kits) degradation and promoting apoptosis

  4. Data indicate taht m2R-RGS6-IKACh pathway sets heart rate variability independently from the autonomic input.

  5. Data indicate that genetic ablation of RGS6 expression resulted in anxiolytic and antidepressant behavior by enhancing signaling through the 5-HT1A receptor (show CC2D1A ELISA Kits)-adenylyl cyclase (AC) axis.

  6. RGS6-Gbeta5 (show GNB5 ELISA Kits), but not RGS4 (show RGS4 ELISA Kits), is the primary RGS (show PITX2 ELISA Kits) modulator of parasympathetic HR regulation and SAN M2R-IKACh signaling in mice.

  7. Spontaneous tumor formation was also seen in old female RGS6(-/-) but not in wild-type mice.

  8. results identify RGS6 as an essential mediator of the pathogenic responses to doxorubicin in heart, and they argue that RGS6 inhibition offers a rational means to circumvent doxorubicin cardiotoxicity in human patients with cancer

  9. establish RGS6 as a key component of GABA(B)R signaling

  10. Regulator of G-protein signaling 6 (RGS6) is a previously unrecognized, but essential, negative regulator of parasympathetic activation in heart.

RGS6 Antigen Profile

Antigen Summary

This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.

Alternative names and synonyms associated with RGS6

  • regulator of G-protein signaling 6 (RGS6) Elisa Kit
  • regulator of G-protein signaling 6 (Rgs6) Elisa Kit
  • regulator of G-protein signaling 6 (rgs6) Elisa Kit
  • regulator of G-protein signalling 6 (rgs6) Elisa Kit
  • DKFZp459O0734 Elisa Kit
  • GAP Elisa Kit
  • hm:zeh0300 Elisa Kit
  • RGS6 Elisa Kit
  • si:ch211-268e23.2 Elisa Kit

Protein level used designations for RGS6

regulator of G-protein signaling 6 , regulator of G-protein signalling 6 , regulator of G-protein signaling 6-like , GTPase activating protein , H_DJ1108A12.1 , S914 , WUGSC:H_DJ0283M22.1 , WUGSC:H_DJ1108A12.1

GENE ID SPECIES
453009 Pan troglodytes
517545 Bos taurus
694620 Macaca mulatta
100024815 Monodelphis domestica
100055109 Equus caballus
100172360 Pongo abelii
100387876 Callithrix jacchus
100549212 Meleagris gallopavo
100579925 Nomascus leucogenys
9628 Homo sapiens
50779 Mus musculus
54295 Rattus norvegicus
734690 Xenopus laevis
395618 Gallus gallus
562667 Danio rerio
480380 Canis lupus familiaris
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