Browse our UCP2 (UCP2) ELISA Kits

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Uncoupling Protein 2 (Mitochondrial, Proton Carrier) ELISA Kits (UCP2)
On are 27 Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) ELISA Kits from 8 different suppliers available. Additionally we are shipping UCP2 Antibodies (135) and UCP2 Proteins (9) and many more products for this protein. A total of 178 UCP2 products are currently listed.
ATUCP2, BMIQ4, cb74, DKFZp470P1633, K19M22.21, K19M22_21, MGC53319, MGC75881, Slc25a8, ucp2, UCPH, uncoupling protein 2

Top referenced UCP2 ELISA Kits

  1. Human UCP2 ELISA Kit for Sandwich ELISA - ABIN418273 : Aslan, Kader, Mutlu, Sarıaydın, Aran, Alver, Kahraman: The effect of delivery type on uncoupling protein-2 levels. in The journal of maternal-fetal & neonatal medicine 2016 (PubMed)

  2. Rat (Rattus) UCP2 ELISA Kit for Sandwich ELISA - ABIN432943 : Rodríguez-Jimnez, Alastrue-Agudo, Erceg, Stojkovic, Moreno-Manzano: FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction. in Stem cells (Dayton, Ohio) 2012 (PubMed)

More ELISA Kits for UCP2 Interaction Partners

Zebrafish Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. except for reduced lipid peroxidation, we did not observe any significant reactive oxygen species reduction associated with increased Ucp2 activation in cold-exposed group.

Human Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. effects of UCP2 polymorphisms on the brain

  2. genetic association studies on population in Brazil: Data suggest that a missense mutation (rs660339, Ala55Val) and an SNP (rs659366, -866G>A) in UCP2 are associated with weight loss in patients with morbid obesity following Roux-en-Y gastric bypass; individuals who carry T (CT+TT) and A (GA+AA) mutated alleles for Ala55Val and -866G>A, respectively, exhibit higher weight loss and fat-free (show VPS51 ELISA Kits) mass loss.

  3. Dominant UCP2 mutations are a more important cause of congenital hyperinsulinism than has been recognized and that affected individuals are markedly hypersensitive to glucose-induced hypoglycemia.

  4. UCP2 has an apoptotic effect in beta cells via regulation of the intrinsic pathway of apoptosis in brain dead organ donors.

  5. genetic association studies in population in Brazil: Data suggest that two SNPs in UCP2 (rs660339, Ala55Val; rs659366, -866G>A) are associated with ability of patients to comply with dietary restrictions follow bariatric surgery for morbid obesity; thus, UCP2 may be involved in appetite regulation and/or satiety response.

  6. The 'AA' genotype of UCP2 promoter gene polymorphism G to A at - 866 position revealed 12.39 folds risk for presbycusis.

  7. Estrogens may increase mitochondrial reactive oxygen species production by repressing uncoupling proteins including UCP2.

  8. UCP2 as a selective modulator of single channel MCU (show MCU ELISA Kits) dependent mitochondrial Ca2 (show CA2 ELISA Kits)+ inward current.

  9. GTPBP3 (show GTPBP3 ELISA Kits) plays a role in the regulation of UCP2 protein through AMPK (show PRKAA1 ELISA Kits) signaling.

  10. We conclude that UCP2 neither mediates palmitate-induced mitochondrial ROS (show ROS1 ELISA Kits) generation and the associated cell loss, nor protects against these deleterious effects. Instead, UCP2 dampens palmitoleate protection against palmitate toxicity.

Mouse (Murine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. This study demonstrating a FABP4 (show FABP4 ELISA Kits)-UCP2 axis with the potential to modulate the microglial inflammatory response.

  2. The miR (show MLXIP ELISA Kits)-133a-UCP2 pathway participates in inflammatory bowel disease (IBD) by altering downstream inflammation, oxidative stress and markers of energy metabolism, which provides novel clues and potential therapeutic targets for IBD.

  3. PPARgamma (show PPARG ELISA Kits) inhibited PDGF (show PDGFA ELISA Kits)-BB-induced ROS (show ROS1 ELISA Kits) in VSMCs by upregulating UCP2 expression.

  4. these data offer a novel pathway whereby FABP4/aP2 regulates macrophage redox signaling and inflammasome activation via control of UCP2 expression.

  5. Ucp2 affects glutathione metabolism by regulating hepatic efflux of glutathione. Nrf2 (show NFE2L2 ELISA Kits) deficiency may not aggravate oxidative stress in Ucp2-deficient mice.

  6. Induction of autophagy by SCFAs required PPARgamma (show PPARG ELISA Kits) stimulation of Uncoupling Protein 2 (UCP2) expression that was associated with reduced intracellular ATP levels and activation of PRKAA1/AMPK (show PRKAA1 ELISA Kits) (protein kinase (show CDK7 ELISA Kits), AMP (show TMPRSS5 ELISA Kits)-activated, alpha 1 catalytic subunit). In addition, elimination of gut (show GUSB ELISA Kits) flora by chronic antibiotic treatment diminished basal hepatic autophagy in mice suggesting that gut (show GUSB ELISA Kits) microbiota can regulate hepatic auto...

  7. UCP2 induces protective effects on ROS (show ROS1 ELISA Kits) and ATP levels during aging. Additionally, the results suggest an imbalance in hematopoiesis because of the lack of UCP2.

  8. Intriguingly, on the molecular level this acceleration in aging predominantly is accompanied by increased levels of circulating IGF-1 (show IGF1 ELISA Kits) in Ucp2(-/-) mice, hinting at a crosstalk between UCP2 and the classical Insulin (show INS ELISA Kits)/IGF-1 (show IGF1 ELISA Kits) signaling aging pathway.

  9. PPARbeta (show PPARD ELISA Kits)/PPARgamma (show PPARG ELISA Kits) activation restored the LPS (show TLR4 ELISA Kits)-induced endothelial dysfunction by upregulation of UCP2, with the subsequent alleviation of ER stress and NADPH oxidase (show NOX1 ELISA Kits) activity, thus reducing intracellular reactive oxygen species production and increasing nitric oxide bioavailability.

  10. Apart from their slower growth, pancreatic stellate cells of UCP2-/- mice displayed no functional abnormalities.

Pig (Porcine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. Despite patent grafts, revascularized hibernating myocardium demonstrates a submaximal response to dobutamine infusion and increased mitochondrial UCP-2 expression.

  2. Seven deletion polymorphisms were covered in introns of linkage genes of UCP2 and UCP3 (show UCP3 ELISA Kits), showing that UCPs have conservation and genetic reliability.

  3. The in vivo data indicate that beta-adrenergic agonists may function in regulating UCP2 and UCP3 (show UCP3 ELISA Kits) expression in selected muscles.

Cow (Bovine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. UCPs do have uncoupling properties when expressed in mitochondria but that uncoupling by UCP1 (show UCP1 ELISA Kits) or UCP2 does not prevent acute substrate-driven endothelial cell superoxide as effluxed from mitochondria respiring in vitro.

  2. A study evaluating the relationships of uncoupling protein 2 and 3 expression, SNP of mitochondrial DNA, and residual feed intake (RFI (show RNF34 ELISA Kits)) in Angus steers selected to have high or low RFI (show RNF34 ELISA Kits) is presented.

  3. These results suggest that UCP2 play an important role of lipid and energy metabolism in mammary epithelial cells.

UCP2 Antigen Profile

Antigen Summary

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

Alternative names and synonyms associated with UCP2

  • mitochondrial uncoupling protein 2 (PTRG_09289) Elisa Kit
  • uncoupling protein 2 (mitochondrial, proton carrier) (UCP2) Elisa Kit
  • mitochondrial uncoupling protein 2 (LOC100282746) Elisa Kit
  • uncoupling protein 2 (ucp2) Elisa Kit
  • uncoupling protein 2 (mitochondrial, proton carrier) (TEgg068n20.1) Elisa Kit
  • uncoupling protein 2 (UCP2) Elisa Kit
  • uncoupling protein 2 (LOC100534553) Elisa Kit
  • uncoupling protein 2 (mitochondrial, proton carrier) (Ucp2) Elisa Kit
  • ATUCP2 Elisa Kit
  • BMIQ4 Elisa Kit
  • cb74 Elisa Kit
  • DKFZp470P1633 Elisa Kit
  • K19M22.21 Elisa Kit
  • K19M22_21 Elisa Kit
  • MGC53319 Elisa Kit
  • MGC75881 Elisa Kit
  • Slc25a8 Elisa Kit
  • ucp2 Elisa Kit
  • UCPH Elisa Kit
  • uncoupling protein 2 Elisa Kit

Protein level used designations for UCP2

mitochondrial uncoupling protein 2 , uncoupling protein 2 (mitochondrial, proton carrier) , Mitochondrial uncoupling protein 2 , uncoupling protein 2 , UCP 2 , solute carrier family 25 member 8 , zUCP2 , UCPH , uncoupling protein 2, mitochondrial , uncoupling protein homolog , Uncoupling protein 2, mitochondrial

6347579 Pyrenophora tritici-repentis Pt-1C-BFP
100173815 Pongo abelii
100282746 Zea mays
379915 Xenopus laevis
394786 Xenopus (Silurana) tropicalis
555812 Danio rerio
574198 Macaca mulatta
836014 Arabidopsis thaliana
100534553 Oreochromis niloticus
7351 Homo sapiens
22228 Mus musculus
397549 Sus scrofa
54315 Rattus norvegicus
281562 Bos taurus
403576 Canis lupus familiaris
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