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Human Urotensin 2 Primary Antibody for ELISA - ABIN367609
Liu, Li, Xu, Chen, Chen: Neurokinin B and urotensin II levels in pre-eclampsia. in The journal of maternal-fetal & neonatal medicine 2010
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UII/GPR14 (show UTS2R ELISA Kits) signaling was involved in the DSS (show NR0B1 ELISA Kits)-induced colonic inflammation and its inhibition may serve as a potential therapeutic target, which may be associated with the NF-kappaB (show NFKB1 ELISA Kits) signaling pathway.
Ser89Asn polymorphisms of the UTS2 gene are significantly associated with atrial fibrillation in the Chinese population. Additionally, we demonstrated that genotype Met21Met may have a potential beneficial role in atrial fibrillation.
Serum urotensin II levels were significantly lower in hemodialysis patients compared to healthy subjects.
expression of UII is associated with ERS in patients with SPE. Our results indicate that UII may trigger ERS in placental trophoblastic cells in patients with preeclampsia.
Our study suggests that U-II may play a role in migraine pathogenesis; also Thr21Met polymorphism was associated with the risk of migraine disease.
Used transgenic rabbits as a model to study macrophage-specific expressing human UII (hUII) and studied the role of autocrine UII in the development of atherosclerosis.
Urotensin II-increased reactive oxygen species production via the NADPH oxidase (show NOX1 ELISA Kits) pathway is partially associated with activation of the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits) cascades
provide evidence that, in glioma cells, homogeneous concentration of UII allowed translocation of Galpha13 to the UT receptor (show UTS2R ELISA Kits) at the plasma membrane and increased actin stress fibers, lamellipodia formation and vinculin (show VCL ELISA Kits)-stained focal adhesions
enzyme-linked immunosorbent assay (ELISA) and restriction fragment length polymorphism analysis were used to evaluate plasma levels of urotensin-II and Thr21Met and Ser89Asn polymorphisms of UTS2 gene in breast cancer patients.
Urotensin II can induce the proliferation of BEL (show LHX2 ELISA Kits)-7402 cells via the urotensin receptor (show UTS2R ELISA Kits) mediated PKC/ERK/p38 MAPK (show MAPK1 ELISA Kits) signaling pathways.
Urotensin II plays a role in the pathogenesis and priming of acute liver failure by triggering an inflammatory cascade and driving the early release of TNF-alpha (show TNF ELISA Kits) and Il1beta (show IL1B ELISA Kits).
UII/UTR (show UTS2R ELISA Kits) system plays a role in lipopolysaccharide (LPS (show TLR4 ELISA Kits))/D-galactosamine (GalN (show GAL ELISA Kits))-induced acute liver failure.
Data suggest that aortic urotensin II (UII) is increased in diabetes-associated atherosclerosis in humans and mice; diabetes-associated plaque development is attenuated by UII/UII receptor antagonism in in vitro (human) and in vivo (mouse) settings.
It is believed that U-II is an important mediator in Systemic sclerosis.
role of urotensin II gene deletion in atherosclerosis and suggest that the use of pharmaceutical agents aimed at blocking the urotensin II pathway may provide a novel approach in the treatment of atherosclerosis.
mouse UII is expressed in a subpopulation of motoneurons in the spinal cord
In the CNS UII mRNAs are expressed in brainstem and spinal motoneurons, also expressed in the medial vestibular nucleus, locus coeruleus and the ventral medulla.
increased plasma urotensin II level stimulates oxidized low-density lipoprotein and reactive oxygen species production and macrophage foam cell formation
Elevated expression of Uts2 in skeletal muscle of diabetic mouse is reported.
This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.
, prepro U-II
, urotensin II
, urocortin 2