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Browse our Urotensin 2 Proteins (UTS2)

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Urotensin 2 Proteins (UTS2)
On are 4 Urotensin 2 (UTS2) Proteins from 4 different suppliers available. Additionally we are shipping Urotensin 2 Antibodies (88) and Urotensin 2 Kits (40) and many more products for this protein. A total of 162 Urotensin 2 products are currently listed.
prepro-UII, PRO1068, U-II, Ucn2, UII, UTS2
list all proteins Gene Name GeneID UniProt
UTS2 10911 O95399
Rat UTS2 UTS2 29180 Q9QZQ4
Mouse UTS2 UTS2 24111 Q9QZQ3

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Urotensin 2 Proteins (UTS2) by Origin

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Human Urotensin 2 (UTS2) interaction partners

  1. UII/GPR14 signaling was involved in the DSS (show NR0B1 Proteins)-induced colonic inflammation and its inhibition may serve as a potential therapeutic target, which may be associated with the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  2. Ser89Asn polymorphisms of the UTS2 gene are significantly associated with atrial fibrillation in the Chinese population. Additionally, we demonstrated that genotype Met21Met may have a potential beneficial role in atrial fibrillation.

  3. Serum urotensin II levels were significantly lower in hemodialysis patients compared to healthy subjects.

  4. expression of UII is associated with ERS in patients with SPE. Our results indicate that UII may trigger ERS in placental trophoblastic cells in patients with preeclampsia.

  5. Our study suggests that U-II may play a role in migraine pathogenesis; also Thr21Met polymorphism was associated with the risk of migraine disease.

  6. Used transgenic rabbits as a model to study macrophage-specific expressing human UII (hUII) and studied the role of autocrine UII in the development of atherosclerosis.

  7. Urotensin II-increased reactive oxygen species production via the NADPH oxidase (show NOX1 Proteins) pathway is partially associated with activation of the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) and ERK (show EPHB2 Proteins) cascades

  8. provide evidence that, in glioma cells, homogeneous concentration of UII allowed translocation of Galpha13 (show GNA13 Proteins) to the UT receptor at the plasma membrane and increased actin stress fibers, lamellipodia formation and vinculin (show VCL Proteins)-stained focal adhesions

  9. enzyme-linked immunosorbent assay (ELISA) and restriction fragment length polymorphism analysis were used to evaluate plasma levels of urotensin-II and Thr21Met and Ser89Asn polymorphisms of UTS2 gene in breast cancer patients.

  10. Urotensin II can induce the proliferation of BEL (show LHX2 Proteins)-7402 cells via the urotensin receptor mediated PKC (show PRRT2 Proteins)/ERK/p38 MAPK (show MAPK1 Proteins) signaling pathways.

Mouse (Murine) Urotensin 2 (UTS2) interaction partners

  1. Urotensin II plays a role in the pathogenesis and priming of acute liver failure by triggering an inflammatory cascade and driving the early release of TNF-alpha (show TNF Proteins) and Il1beta (show IL1B Proteins).

  2. UII/UTR system plays a role in lipopolysaccharide (LPS (show TLR4 Proteins))/D-galactosamine (GalN (show GAL Proteins))-induced acute liver failure.

  3. Data suggest that aortic urotensin II (UII) is increased in diabetes-associated atherosclerosis in humans and mice; diabetes-associated plaque development is attenuated by UII/UII receptor antagonism in in vitro (human) and in vivo (mouse) settings.

  4. It is believed that U-II is an important mediator in Systemic sclerosis.

  5. role of urotensin II gene deletion in atherosclerosis and suggest that the use of pharmaceutical agents aimed at blocking the urotensin II pathway may provide a novel approach in the treatment of atherosclerosis.

  6. mouse UII is expressed in a subpopulation of motoneurons in the spinal cord

  7. In the CNS UII mRNAs are expressed in brainstem and spinal motoneurons, also expressed in the medial vestibular nucleus, locus coeruleus and the ventral medulla.

  8. increased plasma urotensin II level stimulates oxidized low-density lipoprotein and reactive oxygen species production and macrophage foam cell formation

  9. Elevated expression of Uts2 in skeletal muscle of diabetic mouse is reported.

Urotensin 2 (UTS2) Protein Profile

Protein Summary

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.

Alternative names and synonyms associated with Urotensin 2 (UTS2)

  • urotensin 2 (UTS2)
  • urotensin 2 (uts2)
  • urotensin 2 (Uts2)
  • prepro-UII protein
  • PRO1068 protein
  • U-II protein
  • Ucn2 protein
  • UII protein
  • UTS2 protein

Protein level used designations for Urotensin 2 Proteins (UTS2)

urotensin 2 , prepro U-II , urotensin II , urotensin-2 , U-II , UII , urocortin 2 , urotensin-II

746007 Pan troglodytes
100379687 Xenopus (Silurana) tropicalis
10911 Homo sapiens
29180 Rattus norvegicus
24111 Mus musculus
397268 Sus scrofa
574246 Macaca mulatta
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