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SUMOylation of human septins is critical for septin (show SEPT6 ELISA Kits) filament bundling and cytokinesis.
Data indicate that forchlorfenuron (FCF) exhibits differential binding preference for septins SEPT2 (show SEPT2 ELISA Kits) and SEPT3.
septins from the SEPT3 subgroup may be important determinants of polymerization by occupying the terminal position in octameric units which themselves form the building blocks of at least some heterofilaments
Data show that Septins of the SEPT6 (show SEPT6 ELISA Kits) group preferentially interacted with septins of the SEPT2 (show SEPT2 ELISA Kits) group, SEPT3 group and SEPT7 (show SEPT7 ELISA Kits) group.
Sept3 is dispensable for normal neuronal development
SEPT3 and SEPT5 (show SEPT5 ELISA Kits) are dispensable for neuronal development as well as for synaptic vesicle fusion and recycling.
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
neuronal-specific septin 3
, neuronal-specific septin-3
, G-septin alpha
, septin 3
, septin 12
, putative septin 3 variant 1
, neuronal-specific septin-3-like