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Browse our anti-Arhgef9 (Arhgef9) Antibodies

Full name:
anti-Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 Antibodies (Arhgef9)
On are 53 Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) Antibodies from 18 different suppliers available. Additionally we are shipping Arhgef9 Proteins (5) and many more products for this protein. A total of 61 Arhgef9 products are currently listed.
9630036L12Rik, A230067K14, ARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, mKIAA0424, PEM-2, PEM2, wu:fj33b10
list all antibodies Gene Name GeneID UniProt
Arhgef9 23229 O43307
Arhgef9 66013 Q9QX73
Arhgef9 236915 Q3UTH8

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anti-Human Arhgef9 Antibodies:

anti-Rat (Rattus) Arhgef9 Antibodies:

anti-Mouse (Murine) Arhgef9 Antibodies:

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Top referenced anti-Arhgef9 Antibodies

  1. Human Polyclonal Arhgef9 Primary Antibody for EIA, IHC (p) - ABIN357844 : Xiang, Kim, Connelly, Nassar, Kirsch, Winking, Schwarz, Schindelin: The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor. in Journal of molecular biology 2006 (PubMed)
    Show all 4 references for ABIN357844

  2. Human Polyclonal Arhgef9 Primary Antibody for IHC (p), WB - ABIN389168 : Grosskreutz, Hermann, Kins, Fuhrmann, Betz, Kneussel: Identification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistin. in Biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN389168

  3. Human Polyclonal Arhgef9 Primary Antibody for IHC, ELISA - ABIN1535302 : Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005 (PubMed)

More Antibodies against Arhgef9 Interaction Partners

Human Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) interaction partners

  1. Collybistin forms a complex with mTOR (show FRAP1 Antibodies) and eIF3 (show EIF3A Antibodies) and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  2. Impairment of the membrane lipid binding activity of Collybistin R290H and a consequent defect in inhibitory synapse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in humans.

  3. The enhancement of Cb-induced gephyrin (show GPHN Antibodies) clustering by GTP (show AK3 Antibodies)-TC10 (show RHOQ Antibodies) does not depend on the guanine nucleotide exchange activity of Cb but involves an interaction that resembles reported interactions of other small GTPases with their effectors

  4. Phosphorylation of gephyrin (show GPHN Antibodies) in hippocampal neurons by cyclin-dependent kinase (show CDK1 Antibodies) CDK5 (show CDK5 Antibodies) at Ser (show SIGLEC1 Antibodies)-270 is dependent on collybistin.

  5. Data indicate that ARHGEF9 is likely to be responsible for syndromic X-linked mental retardation associated with epilepsy.

  6. These results reveal that G(s) and G(q) signalings regulate hPEM-2 functions through PKA and c-Src (show SRC Antibodies) in Neuro-2a neuroblastoma (show ARHGEF16 Antibodies) cells, respectively.

  7. major regulator of GABAergic postsynaptic gephyrin (show GPHN Antibodies) clustering

  8. Study propose that the collybistin-gephyrin (show GPHN Antibodies) complex has an intimate role in the clustering of GABA(A)Rs containing the alpha2 subunit.

  9. Here we identified residues critical for interaction with gephyrin (show GPHN Antibodies) in the linker region between the SH3 and the DH domains of collybistin.

  10. translocates gephyrin (show GPHN Antibodies) to submembrane microaggregates; collybistin mutation (G55A)is found in exon 2 of the ARHGEF9 gene in a patient with clinical symptoms of both hyperekplexia and epilepsy

Mouse (Murine) Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) interaction partners

  1. Within this network, collybistin can adopt open/active and closed/inactive conformations to act as a switchable adaptor that links gephyrin (show GPHN Antibodies) to plasma membrane phosphoinositides.

  2. data show that collybistin co-clusters with gephyrin (show GPHN Antibodies) and GABA(A) Rs in synaptic puncta and is recruited to postsynaptic specializations early during synapse development; it co-localizes with GABA(A) Rs containing the alpha1, alpha2, or alpha3 subunits

  3. The results of this study provided evidence that the formation of gephyrin (show GPHN Antibodies) scaffolds at inhibitory synapses requires an intact Cb II PH-domain but is Cdc42 (show CDC42 Antibodies)-independent.

  4. The resolution crystal structure of the Cdc42 (show CDC42 Antibodies)-collybistin II complex reveals a novel conformation of the switch I region of Cdc42 (show CDC42 Antibodies), and biochemical data indicate that gephyrin (show GPHN Antibodies) negatively regulates collybistin activity.

  5. Cb is essential for gephyrin (show GPHN Antibodies)-dependent clustering of a specific set of GABA(A) receptors, but not required for glycine receptor (show GLRB Antibodies) postsynaptic localization.

  6. Data provide the first evidence that collybistin deficiency leads to significant changes of GABAergic inhibition, network excitability and synaptic plasticity in vivo.

Arhgef9 Antigen Profile

Antigen Summary

The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Arhgef9

  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (ARHGEF9) antibody
  • Cdc42 guanine nucleotide exchange factor (GEF) 9b (arhgef9b) antibody
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (arhgef9) antibody
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) antibody
  • CDC42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) antibody
  • rho guanine nucleotide exchange factor 9-like (LOC537718) antibody
  • 9630036L12Rik antibody
  • A230067K14 antibody
  • ARHGEF9 antibody
  • COLLYBISTIN antibody
  • EIEE8 antibody
  • HPEM-2 antibody
  • mKIAA0424 antibody
  • PEM-2 antibody
  • PEM2 antibody
  • wu:fj33b10 antibody

Protein level used designations for Arhgef9

Cdc42 guanine nucleotide exchange factor (GEF) 9 , Cdc42 guanine nucleotide exchange factor 9 , Cdc42 guanine exchange factor 9 , rho guanine nucleotide exchange factor 9-like , PEM-2 homolog , hPEM-2 collybistin , rac/Cdc42 guanine nucleotide exchange factor 9 , rho guanine nucleotide exchange factor 9 , collybistin I , collybistin

422315 Gallus gallus
465666 Pan troglodytes
560923 Danio rerio
100018406 Monodelphis domestica
100054217 Equus caballus
100125033 Xenopus (Silurana) tropicalis
100338091 Oryctolagus cuniculus
100393157 Callithrix jacchus
100512575 Sus scrofa
100586595 Nomascus leucogenys
23229 Homo sapiens
66013 Rattus norvegicus
236915 Mus musculus
100171927 Pongo abelii
537718 Bos taurus
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