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Browse our DUSP6 (DUSP6) ELISA Kits

Full name:
Dual Specificity Phosphatase 6 ELISA Kits (DUSP6)
On www.antibodies-online.com are 3 Dual Specificity Phosphatase 6 (DUSP6) ELISA Kits from 3 different suppliers available. Additionally we are shipping DUSP6 Antibodies (123) and DUSP6 Proteins (6) and many more products for this protein. A total of 141 DUSP6 products are currently listed.
Synonyms:
1300019I03Rik, dusp6, fd19d04, HH19, MKP-3, MKP3, PYST1, wu:fd19d04, wu:fd99d09, zgc:55957, zgc:77211
list all ELISA KIts Gene Name GeneID UniProt
DUSP6 1848 Q16828
Mouse DUSP6 DUSP6 67603 Q9DBB1
Rat DUSP6 DUSP6 116663 Q64346

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DUSP6 (DUSP6) ELISA Kits by Reactivity

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More ELISA Kits for DUSP6 Interaction Partners

Zebrafish Dual Specificity Phosphatase 6 (DUSP6) interaction partners

  1. Lef1 (show LEF1 ELISA Kits) has a role in regulating Dusp6 in formation of the zebrafish posterior lateral line primordium

  2. During fin development, dusp6, a known MAPK/ERK (show MAPK1 ELISA Kits) regulator, is induced in the mesoderm by FGF8 (show FGF8 ELISA Kits) signaling, through the PI3 (show PI3 ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway.

  3. During fin development, dusp6, a known MAPK/ERK (show MAPK1 ELISA Kits) regulator, is induced in the mesoderm by FGF8 (show FGF8 ELISA Kits) signaling, through the PI3 (show PI3 ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway.

  4. Mkp3 encodes a feedback attenuator of the FGF pathway, the expression of which is initiated at an early stage so as to ensure correct FGF signaling levels at the time of axial patterning.

Xenopus laevis Dual Specificity Phosphatase 6 (DUSP6) interaction partners

  1. Retinoic acid-dependent control of MAP kinase phosphatase-3 is necessary for early kidney development.

Human Dual Specificity Phosphatase 6 (DUSP6) interaction partners

  1. DNA samples from each patient were genotyped for DUSP6 and TOP2A (show TOP2A ELISA Kits) SNPs

  2. Suppression of the FOXA1 (show FOXA1 ELISA Kits)/DUSP6 signaling pathway may contribute to the development of Hirschsprung disease.

  3. These observations led us to conclude that increased TSH signaling overcomes OIS and is essential for B-RafV600E-induced papillary thyroid carcinogenesis.

  4. Dusp6 expression was higher in progestin-sensitive atypical endometrial hyperplasia groups compared with progestin-resistant groups. After treatment, Dusp6 expression was upregulated in progestin-sensitive groups, but not in progestin-resistant groups.

  5. Our results suggest that DUSP6 gene expression in tumour samples may be a prognostic marker in NSCLC

  6. DUSP6 downregulated the expression of matrix metallopeptidase 3 (show MMP3 ELISA Kits).

  7. These results therefore indicate that p53 (show TP53 ELISA Kits)-mediated up-regulation of MKP-3 contributes to the establishment of the senescent cellular phenotype through dephosphorylating ERK1/2 (show MAPK1/3 ELISA Kits)

  8. Downregulation of Dusp6, Sprouty4 (show SPRY4 ELISA Kits), and Sef (show TFCP2 ELISA Kits)--negative modulators of FGF2 (show FGF2 ELISA Kits)/ERK1/2 (show MAPK1/3 ELISA Kits) signaling--was present in eutopic endometria of adenomyosis, which may play critical roles in the development of adenomyosis.

  9. Higher expression of DUSP6 in tumor tissue, than in peritumor tissue, is associated with the recurrence after curative resection of HCC (show FAM126A ELISA Kits), and the relative tumor DUSP6 expression has good power to predict the recurrence of HCC (show FAM126A ELISA Kits).

  10. suggest an important role for DeltaNp63alpha in preventing cancer metastasis by inhibition of Erk2 (show MAPK1 ELISA Kits) signaling via MKP3 subscribing

Mouse (Murine) Dual Specificity Phosphatase 6 (DUSP6) interaction partners

  1. MKP3 could be an important factor in the regulation of brown adipocyte differentiation.

  2. DUSP6 regulates CD4 (show CD4 ELISA Kits)+ T-cell activation and differentiation by inhibiting the TCR-dependent ERK1/2 (show MAPK1/3 ELISA Kits) activation and restraining spontaneous colitis in IL-10 (show IL10 ELISA Kits)-deficient mice.

  3. exercised obese mice had a lower expression of MKP-3 and FoxO1 (show FOXO1 ELISA Kits)/MKP-3 association in the liver

  4. c-Myb (show MYB ELISA Kits) plays an important role in H-Ras (show HRAS ELISA Kits)-induced MKP-3 transcription

  5. Mice lacking MKP-3 protein develop an abnormal persistent state of mechanical allodynia following plantar incision, concurrent with long-lasting spinal phosphorylation of ERK-1 (show MAPK3 ELISA Kits)/2 and p38 (show CRK ELISA Kits).

  6. Depletion of DUSP6 reduced the viability of cancer cell lines and increased the cytotoxicity of EGFR (show EGFR ELISA Kits) and other targeted inhibitors, and cytotoxic agents.

  7. LH/hCG (show CGA ELISA Kits) tightly up-regulates MKP-3 which in turn, dephosphorylates ERK1/2 (show MAPK1/3 ELISA Kits) and drives p21 expression.

  8. dual specificity phosphatases (Dusps) 6 and 14 are up-regulated by activation of beta-catenin (show CTNNB1 ELISA Kits) in murine liver cells

  9. Constitutively active FOXO1 (show FOXO1 ELISA Kits) can rescue the hypoglycemic effect caused by reduced hepatic MKP-3 expression in vivo.

  10. Insulin (show INS ELISA Kits) likely promotes MKP-3 protein degradation through activation of MEK (show MDK ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway in liver cells.

DUSP6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with DUSP6

  • dual specificity phosphatase 7 (dusp7) Elisa Kit
  • dual specificity phosphatase 6 (dusp6) Elisa Kit
  • dual specificity phosphatase 6 (DUSP6) Elisa Kit
  • dual specificity phosphatase 6 (LOC100222847) Elisa Kit
  • Dual specificity protein phosphatase 6 (dus6) Elisa Kit
  • dual specificity phosphatase 6 (Dusp6) Elisa Kit
  • 1300019I03Rik Elisa Kit
  • dusp6 Elisa Kit
  • fd19d04 Elisa Kit
  • HH19 Elisa Kit
  • MKP-3 Elisa Kit
  • MKP3 Elisa Kit
  • PYST1 Elisa Kit
  • wu:fd19d04 Elisa Kit
  • wu:fd99d09 Elisa Kit
  • zgc:55957 Elisa Kit
  • zgc:77211 Elisa Kit

Protein level used designations for DUSP6

dual specificity phosphatase 6 , dual specificity protein phosphatase 7 , dual specificity protein phosphatase 6 , etID14116.25 , MAP kinase phosphatase X17C , Dual specificity protein phosphatase 6 , dual specificity protein phosphatase 6-like , MAP kinase phosphatase 3 , dual specificity protein phosphatase PYST1 , mitogen-activated protein kinase phosphatase 3 , serine/threonine specific protein phosphatase , MKP-3

GENE ID SPECIES
327246 Danio rerio
353314 Danio rerio
374272 Gallus gallus
398829 Xenopus laevis
452115 Pan troglodytes
733815 Xenopus (Silurana) tropicalis
100137150 Takifugu rubripes
100222847 Taeniopygia guttata
100306828 Salmo salar
100409879 Callithrix jacchus
100466694 Ailuropoda melanoleuca
100051565 Equus caballus
100136684 Oncorhynchus mykiss
100460800 Pongo abelii
100588912 Nomascus leucogenys
1848 Homo sapiens
67603 Mus musculus
116663 Rattus norvegicus
515310 Bos taurus
482594 Canis lupus familiaris
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