Browse our Histone Deacetylase 2 Proteins (HDAC2)

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Histone Deacetylase 2 Proteins (HDAC2)
On are 8 Histone Deacetylase 2 (HDAC2) Proteins from 5 different suppliers available. Additionally we are shipping Histone Deacetylase 2 Antibodies (257) and Histone Deacetylase 2 Kits (44) and many more products for this protein. A total of 325 Histone Deacetylase 2 products are currently listed.
D10Wsu179e, HD2, HISTONE DEACETYLASE, histone deacetylase 2, mRPD3, RPD3, T1N24.9, T1N24_9, YAF1, Yy1bp
list all proteins Gene Name GeneID UniProt
HDAC2 3066 Q92769
HDAC2 15182 P70288
Rat HDAC2 HDAC2 84577  

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Histone Deacetylase 2 Proteins (HDAC2) by Origin

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Top referenced Histone Deacetylase 2 Proteins

  1. Human HDAC2 Protein expressed in Hi-5 - ABIN667944 : Taunton, Hassig, Schreiber: A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for 667944

More Proteins for Histone Deacetylase 2 Interaction Partners

Human Histone Deacetylase 2 (HDAC2) interaction partners

  1. Results indicate that HCV core induced epithelial-mesenchymal transition (EMT (show ITK Proteins)) by interacting with the transcriptional repressor complex Snail (show SNAI1 Proteins)/HDAC1 (show HDAC1 Proteins)/2 at the E-cadherin (show CDH1 Proteins) promoter, which led to E-cadherin (show CDH1 Proteins) repression and increased invasiveness of hepatoma cells.

  2. Coexpression of SALL4 with HDAC1 and/or HDAC2 was associated with PTEN underexpression and a poor prognosis in hepatocellular carcinoma.

  3. Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (show CREBBP Proteins) and HDAC1-HDAC2 (show HDAC1 Proteins) has been described.

  4. USP4 (show USP4 Proteins) inhibits p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) through deubiquitinating and stabilizing HDAC2

  5. Histone deacetylase (show HDAC1 Proteins) assays confirmed that MIER2 (show MIER2 Proteins), but not MIER3 (show MIER3 Proteins) complexes, have associated deacetylase activity.

  6. HDAC2 controls ciliogenesis independently of Kras, which facilitates Aurora A (show AURKA Proteins) expression. These studies suggest that HDAC2 is a novel regulator of primary cilium formation in PDAC cells.

  7. class I HDACs (HDAC1 (show HDAC1 Proteins), 2, 3 and 8) play a major role in regulating extracellular matrix and Epithelial-mesenchymal transition, whereas class IIa HDACs (HDAC4 (show HDAC4 Proteins) and 5) are less effective.

  8. the current findings implicate the HDAC2/miR (show MLXIP Proteins)-101/AMPK (show PRKAA1 Proteins) pathway as a critical mediator of AD pathogenesis. These studies also highlight the importance of epigenetics in AD and provide novel therapeutic targets.

  9. Increased cancer-specific mortality was significantly associated with HDAC2 expression, mortality was also increased with high HDAC1 (show HDAC1 Proteins) expression.

  10. HDAC2 upregulation is associated with hepatocellular carcinoma.

Mouse (Murine) Histone Deacetylase 2 (HDAC2) interaction partners

  1. Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (show CREBBP Proteins) and HDAC1-HDAC2 (show HDAC1 Proteins) has been described.

  2. Our study indicates that ischemia-induced histone deacetylase 2 upregulation from 5 to 7 d after stroke mediates the secondary functional loss by reducing survival and neuroplasticity of peri (show POSTN Proteins)-infarct neurons as well as augmenting neuroinflammation. Thus, precisely targeting histone deacetylase 2 in the window phase provides a novel therapeutic strategy for stroke recovery.

  3. Taken together, Fam60a is an essential core subunit of a variant Sin3a (show SIN3A Proteins)-Hdac (show HDAC3 Proteins) complex in embryonic stem cells that is required to promote rapid proliferation and prevent unscheduled differentiation.

  4. provide new insight into the upstream regulation of Sap90/Psd95 (show DLG4 Proteins)-associated protein 3 (show HSPB3 Proteins) and establish the essential role of striatal Hdac1 (show HDAC1 Proteins), Hdac2 and MeCP2 (show MECP2 Proteins) for suppression of repetitive behaviors

  5. this study shows that infection-induced miR (show MLXIP Proteins)-21 promotes severe, steroid-insensitive allergic airway disease by suppressing HDAC2

  6. observations suggest that Methamphetamine may induce large-scale transcriptional changes in the Nuc (show SREBF2 Proteins). Accumbens by regulating the expression of several histone deacetylases in part, via HDAC2-dependent mechanisms.

  7. We also found that glucocorticoid receptor (GR (show NR3C1 Proteins))-mediated histone deacetylase 2 (HDAC) 2 expression and activity are reduced in the Trpv1 (show TRPV1 Proteins)(-/-) mice and that HDAC2-regulated, cell-cycle- and neuroplasticity-related molecules are altered

  8. CRISPR/Cas9-mediated disruption of the Hdac2 gene increased Slc2a1 expression, suggesting that it is one of the responsible histone deacetylases (HDACs). These results confirm that b-OHB is a HDAC inhibitor and show that b-OHB plays an important role in fasting-induced epigenetic activation of a glucose transporter gene in the brain.

  9. Data suggest that pathological cardiac hypertrophy involved class I histone deacetylases HDAC1 (show HDAC1 Proteins) and HdAC2, tuberous sclerosis complex 2 (TSC2), and mTOR (show FRAP1 Proteins) srine-threonine kinases (mTOR (show FRAP1 Proteins)).

  10. Social isolation resulted in down-regulation of Hdac2 mRNA expression in the cerebral cortex.

Histone Deacetylase 2 (HDAC2) Protein Profile

Protein Summary

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Histone Deacetylase 2 (HDAC2)

  • histone deacetylase 2 (HDAC2)
  • histone deacetylase 2 (Hdac2)
  • histone deacetylase 2 (hdac2)
  • histone deacetylase 2 (HDA2)
  • histone deacetylase 2-like (LOC100156170)
  • D10Wsu179e protein
  • HD2 protein
  • histone deacetylase 2 protein
  • mRPD3 protein
  • RPD3 protein
  • T1N24.9 protein
  • T1N24_9 protein
  • YAF1 protein
  • Yy1bp protein

Protein level used designations for Histone Deacetylase 2 Proteins (HDAC2)

YY1-associated factor 1 , transcriptional regulator homolog RPD3 , HD2 , YY1 transcription factor-binding protein , histone deacetylase-2

3066 Homo sapiens
475035 Canis lupus familiaris
15182 Mus musculus
84577 Rattus norvegicus
407223 Bos taurus
395635 Gallus gallus
399252 Xenopus laevis
100715675 Cavia porcellus
101107708 Ovis aries
832673 Arabidopsis thaliana
100156170 Sus scrofa
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