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Browse our PKC iota (PRKCI) ELISA Kits

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Protein Kinase C, iota ELISA Kits (PRKCI)
On are 12 Protein Kinase C, iota (PRKCI) ELISA Kits from 2 different suppliers available. Additionally we are shipping PKC iota Antibodies (56) and PKC iota Proteins (11) and many more products for this protein. A total of 84 PKC iota products are currently listed.
2310021H13Rik, AI427505, aPKClambda, aPKC[l], DXS1179E, hal, has, mKIAA4165, nPKC-iota, PKC, PKCI, Pkcl, PKClambda, Prkci, Prkcl
list all ELISA KIts Gene Name GeneID UniProt
PRKCI 690660 P62959
PRKCI 5584 P41743
PRKCI 18759 Q62074

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More ELISA Kits for PKC iota Interaction Partners

Human Protein Kinase C, iota (PRKCI) interaction partners

  1. the results revealed that PRKCI rs546950 variant decreased the risk of prostate cancer in an Iranian population

  2. effects. Further studies indicated that PRKCI knockdown-mediated autophagy was associated with the inactivation of phosphatidylinositol 3-kinase alpha/AKT (show AKT1 ELISA Kits)-mammalian target of rapamycin (show FRAP1 ELISA Kits) (PIK3CA (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)-MTOR (show FRAP1 ELISA Kits)) signaling.

  3. the knockdown of aPKC increases and extends TGFbeta (show TGFB1 ELISA Kits)-induced p38 MAPK (show MAPK14 ELISA Kits) activation, which sensitizes NSCLC cells to undergo apoptosis.

  4. PKCiota binds to Rab14 (show RAB14 ELISA Kits) and that PKCiota requires Rab14 (show RAB14 ELISA Kits) for its correct distribution in cells. As with Rab14 (show RAB14 ELISA Kits), PKCiota protects claudin-2 (show CLDN2 ELISA Kits) from lysosomal degradation and, in consequence, modulates epithelial barrier.

  5. The results indicate that induction and activation of PKClambda promote TNBC growth, invasion and metastasis.

  6. Targeting aPKC disables oncogenic signaling by both the EGFR (show EGFR ELISA Kits) and the proinflammatory cytokine TNFalpha (show TNF ELISA Kits) in glioblastoma.

  7. PRKCI expression is linked with factors pointing to worse prognosis, higher HER2 (show ERBB2 ELISA Kits) levels and a lower survival rate in breast cancer.

  8. These data indicates the existence of a SDF-1alpha induced DGKalpha - atypical PKC - beta1 integrin signaling pathway, which is essential for matrix invasion of carcinoma cells.

  9. PKCiota positively regulated beta-catenin (show CTNNB1 ELISA Kits) through negatively regulated autophagy and depletion of PKCiota promoted apoptosis via autophagic degradation of beta-catenin (show CTNNB1 ELISA Kits) in esophageal cancer cells.

  10. Report up-regulation of MT1-MMP (show MMP14 ELISA Kits) and atypical protein kinase C (show PRKCZ ELISA Kits) in hormone receptor (show NR4A1 ELISA Kits)-negative breast tumors in association with a higher risk of metastasis. Silencing of aPKC impaired delivery of MT1-MMP (show MMP14 ELISA Kits) from storage compartments and inhibited invasion.

Mouse (Murine) Protein Kinase C, iota (PRKCI) interaction partners

  1. Prkci and its downstream partners direct polarized cell division of luminal myocardial cells to drive trabeculation in the nascent heart.

  2. Prkci regulates expansion of various stem cells via Notch (show NOTCH1 ELISA Kits)-dependent pathway.

  3. PKClambda/iota could be a crucial regulator of mitochondrial function and energy metabolism in stem cells and other cellular contexts

  4. Asymmetric division and CD8+ T lymphocyte fate specification is regulated by protein kinase Czeta and protein kinase Clambda.

  5. adenoviral-mediated supplementation of hepatic PKC-lambda induced a diabetic state in heterozygous PKC-lambda knockout mice.

  6. Data indicate that pseudosubstrate arginine residues are key regulators of atypical protein kinase C (show PRKCZ ELISA Kits)-lambda and atypical protein kinase C-zeta (show PRKCZ ELISA Kits).

  7. Loss of aPKClambda in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.

  8. PKClambda/iota was identified as an important factor for actin cytoskeletal regulation in podocytes and Def-6 as a specific downstream target of PKClambda/iota that regulates the activity of small GTPases and subsequently the actin cytoskeleton of podocytes.

  9. Phosphatidylinositol-3,4,5-triphosphate but not phosphatidylinositol-4,5-biphosphate plays an important role in GLUT4 (show SLC2A4 ELISA Kits) upregulation and glucose metabolism mediated by AKT (show AKT1 ELISA Kits)/PKCzeta (show PRKCZ ELISA Kits)/lambda phosphorylation.

  10. FGF21 (show FGF21 ELISA Kits) inhibits hepatic glucose production by the PI3K-dependent activation of protein kinase c iota.

Zebrafish Protein Kinase C, iota (PRKCI) interaction partners

  1. Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta.

  2. a loss of zBves affects the proteins involved in the pathway of the PAR (show AFG3L2 ELISA Kits) junctional complex, especially aPKC, and both aPKC and Bves (show BVES ELISA Kits) are indispensable to claudin expression.

  3. Heart and soul/PRKCi and nagie oko/Mpp5 (show MPP5 ELISA Kits) regulate myocardial coherence and remodeling during cardiac morphogenesis (show XIRP1 ELISA Kits).

  4. PrkCi function and planar divisions are necessary for asymmetric, self-renewing division of spinal cord precursors.

Cow (Bovine) Protein Kinase C, iota (PRKCI) interaction partners

  1. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

PKC iota (PRKCI) Antigen Profile

Antigen Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.

Alternative names and synonyms associated with PKC iota (PRKCI)

  • protein kinase C, iota (PRKCI) Elisa Kit
  • histidine triad nucleotide binding protein 1 (Hint1) Elisa Kit
  • protein kinase C, iota (Prkci) Elisa Kit
  • protein kinase C, iota (LOC100348584) Elisa Kit
  • protein kinase C, iota (prkci) Elisa Kit
  • 2310021H13Rik Elisa Kit
  • AI427505 Elisa Kit
  • aPKClambda Elisa Kit
  • aPKC[l] Elisa Kit
  • DXS1179E Elisa Kit
  • hal Elisa Kit
  • has Elisa Kit
  • mKIAA4165 Elisa Kit
  • nPKC-iota Elisa Kit
  • PKC Elisa Kit
  • PKCI Elisa Kit
  • Pkcl Elisa Kit
  • PKClambda Elisa Kit
  • Prkci Elisa Kit
  • Prkcl Elisa Kit

Protein level used designations for PRKCI

protein kinase C, iota , protein kinase C iota , nPKC-iota , protein kinase C iota type , 17 kDa inhibitor of protein kinase C , PKCI-1 , adenosine 5'-monophosphoramidase , histidine triad nucleotide-binding protein 1 , protein kinase C inhibitor 1 , protein kinase C-interacting protein 1 , PRKC-lambda/iota , aPKC-lambda/iota , atypical protein kinase C-lambda/iota , protein kinase C, lambda , heart and soul protein

450143 Pan troglodytes
574352 Macaca mulatta
100063737 Equus caballus
100166344 Acyrthosiphon pisum
100173964 Pongo abelii
690660 Rattus norvegicus
5584 Homo sapiens
18759 Mus musculus
100348584 Oryctolagus cuniculus
100731983 Cavia porcellus
100174945 Sus scrofa
117507 Danio rerio
478686 Canis lupus familiaris
528478 Bos taurus
424991 Gallus gallus
101118322 Ovis aries
84006 Rattus norvegicus
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