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anti-Human SH3G2 Antibodies:
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Rat (Rattus) Polyclonal SH3G2 Primary Antibody for ICC, IHC - ABIN1742336
Wahl, Katiyar, Schmitz: A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Show all 2 references for ABIN1742336
Human Polyclonal SH3G2 Primary Antibody for WB - ABIN2786766
Sinha, Chunder, Mukherjee, Alam, Roy, Roychoudhury, Kumar Panda: Frequent deletion and methylation in SH3GL2 and CDKN2A loci are associated with early- and late-onset breast carcinoma. in Annals of surgical oncology 2008
Human Monoclonal SH3G2 Primary Antibody for IHC (p), ELISA - ABIN562863
Dasgupta, Jang, Shao, Mukhopadhyay, Sokhi, Das, Brait, Talbot, Yung, Begum, Westra, Hoque, Yang, Yi, Lam, Gazdar, Fisher, Jen, Sidransky: SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling. in Journal of molecular medicine (Berlin, Germany) 2013
Endophilin-1 positively regulated blood-brain barrier permeability via the EGFR (show EGFR Antibodies)-JNK (show MAPK8 Antibodies) signaling pathway in hCMEC/D3 cells, which would provide an experimental basis for further research on endophilin-1 mediated the opening of blood-brain barrier .
these results reveal a novel function of postsynaptic endophilin A1 in spine morphogenesis, stabilization and synaptic function through the regulation of p140Cap (show SRCIN1 Antibodies)
Data indicate that the presence of the susceptible G allele in SNP rs1049430 is associated with the inactivation of SH3-domain GRB2-like 2 protein (SH3GL2) and could be used as a prognostic marker of head and neck squamous cell carcinoma (HNSCC).
study described that endophilin-1 is expressed in hCMEC/D3 cells where it regulates the permeability of blood-brain barrier by altering the expression of ZO-1 (show TJP1 Antibodies) and occludin (show OCLN Antibodies) via the EGFR (show EGFR Antibodies)-ERK1/2 (show MAPK1/3 Antibodies) pathway
miR (show MLXIP Antibodies)-330 negatively regulated the expression of SH3GL2 in GSCs, which promoted the oncogenic progression of GSCs through activating ERK (show EPHB2 Antibodies) and PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathways.
these findings identify loss of Sh3gl2 as a frequent event in Urothelial carcinoma (UC) development that promotes disease progression.
this study suggests a novel mechanism in which Lpd mediates EGFR endocytosis via Mena downstream of endophilin.
Overexpression of EGFR in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes.
Data suggest that expression of endothelin-1 (show EDN1 Antibodies) and vWF (von Willebrand factor (show VWF Antibodies)) is up-regulated and eNOS (endothelial nitric oxide synthase (show NOS3 Antibodies)) activity is increased in radial artery in diabetic patients with coronary artery disease.
Our results indicate that SH3GL2 is frequently deleted in NSCLC and regulates cellular growth and invasion by modulating EGFR (show EGFR Antibodies) function.
retrolinkin is a binding partner of endophilin A1 and that both proteins are required for BDNF (show BDNF Antibodies)-induced dendrite outgrowth
Data report that the parkin ubiquitin-like domain binds SH3 domains from endocytic BAR proteins such as endophilin-A with an affinity comparable to proline-rich domains from well-established SH3 partners.
Tip-to-tip interactions between the BAR domains in a trigonal crystal form of Snx9 (show SNX9 Antibodies)(PX-BAR) reminiscent of functionally important interactions described for F-BAR domains.
Results sugest that reduced or defective OPHN1 (show OPHN1 Antibodies) signaling impairs synaptic vesicle cycling at hippocampal synapses.
interacts with synaptojanin and dynamin I\; may be involved in synaptic vesicle recycling
Endophilin A1 BAR domain
, SH3 domain protein 2A
, SH3 domain-containing GRB2-like protein 2
, bA335L15.1 (SH3-domain GRB2-like 2)
, endophilin A1
, endophilin I
, SH3 domain-containing GRB2-like protein 1