Browse our anti-CD40 (CD40) Antibodies

Full name:
anti-CD40 Molecule, TNF Receptor Superfamily Member 5 Antibodies (CD40)
On www.antibodies-online.com are 919 CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies from 38 different suppliers available. Additionally we are shipping CD40 Kits (66) and CD40 Proteins (64) and many more products for this protein. A total of 1073 CD40 products are currently listed.
Synonyms:
2310042E05Rik, AI326936, Bp50, C87049, C130077D06Rik, CDW40, DCTN-50, GMP23-48K, GP39, HIGM1, IGM, IMD3, p50, RBP50, T-BAM, TNFRSF5, TNFSF5, TRAP
list all antibodies Gene Name GeneID UniProt
CD40 21939 P27512
CD40 958 P25942
CD40 171369  

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Top referenced anti-CD40 Antibodies

  1. Human Monoclonal CD40 Primary Antibody for FACS - ABIN1106360 : Iwamoto, Ishida, Takahashi, Takeda, Miyazaki: Lipopolysaccharide stimulation converts vigorously washed dendritic cells (DCs) to nonexhausted DCs expressing CD70 and evoking long-lasting type 1 T cell responses. in Journal of leukocyte biology 2005 (PubMed)
    Show all 4 references for 1106360

  2. Mouse (Murine) Monoclonal CD40 Primary Antibody for EIA, Func - ABIN118121 : Hasbold, Klaus: B cells from CBA/N mice do not proliferate following ligation of CD40. in European journal of immunology 1994 (PubMed)
    Show all 3 references for 118121

  3. Mouse (Murine) Monoclonal CD40 Primary Antibody for FACS - ABIN118124 : Hasbold, Johnson-Léger, Atkins, Clark, Klaus: Properties of mouse CD40: cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies. in European journal of immunology 1994 (PubMed)
    Show all 3 references for 118124

  4. Mouse (Murine) Monoclonal CD40 Primary Antibody for FACS - ABIN118120 : Parry, Holman, Hasbold, Klaus: Plastic-immobilized anti-mu or anti-delta antibodies induce apoptosis in mature murine B lymphocytes. in European journal of immunology 1994 (PubMed)
    Show all 3 references for 118120

  5. Human Monoclonal CD40 Primary Antibody for FACS - ABIN1106356 : Spirig, van Kooten, Obregon, Nicod, Daha, Rieben: The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for 1106356

  6. Human Polyclonal CD40 Primary Antibody for WB - ABIN222919 : Gao, Wagner, Fankhaenel, Stojanovic, Schweyer, Panzner, Hecker: CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis. in Gut 2004 (PubMed)

  7. Human Polyclonal CD40 Primary Antibody for ELISA, WB - ABIN1531702 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  8. Human Monoclonal CD40 Primary Antibody for FACS - ABIN1106358 : Vermot-Desroches, Marchand, Roy, Wijdenes: Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens. in Immunology letters 1996 (PubMed)

  9. Human Polyclonal CD40 Primary Antibody for WB - ABIN2777069 : von Bergwelt-Baildon, Shimabukuro-Vornhagen, Popov, Klein-Gonzalez, Fiore, Debey, Draube, Maecker, Menezes, Nadler, Schultze: CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. in Blood 2006 (PubMed)

  10. Human Monoclonal CD40 Primary Antibody for FACS - ABIN118630 : Quadbeck, Eckstein, Tews, Walz, Hoermann, Mann, Gieseler: Maturation of thyroidal dendritic cells in Graves' disease. in Scandinavian journal of immunology 2002 (PubMed)

More Antibodies against CD40 Interaction Partners

Mouse (Murine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

  1. CD40 signaling in adipose tissue macrophages regulates major histocompatibility complex class II and CD86 (show CD86 Antibodies) expression to control the expansion of CD4 (show CD4 Antibodies)(+) T cells.

  2. Adoptively transferred Th40 cells (CD4 (show CD4 Antibodies)+CD40+ Tcells) are present in lesions in the CNS and are associated with wide spread demyelination.

  3. this study reports that anti-CD40 mAb administration <3 d in advance of chemotherapy is lethal in more than half of treated C57BL/6 mice in pancreatic cancer model

  4. The data show that CD40-mediated inhibition of PC generation is via engagement of multiple pathway and constitutive CD40 signaling in vivo involving bystander T-B interactions can calibrate B cell differentiation outcomes

  5. BAFF (show TNFSF13B Antibodies) upregulates CD28 (show CD28 Antibodies)/B7 and CD40/CD154 (show CD40LG Antibodies) expression, and promotes the interactions between T and B cells in a BAFF-R (show TNFRSF13C Antibodies)-dependent manner

  6. CD40 in Muller cells is sufficient to upregulate retinal inflammatory markers and appears to promote experimental diabetic retinopathy and that Muller cells orchestrate inflammatory responses in myeloid cells through a CD40-ATP-P2X7 (show P2RX7 Antibodies) pathway.

  7. Taken together, our data demonstrate the importance of CD40 signaling in the conversion of CTL exhaustion and its ability to enhance PD-1 (show PDCD1 Antibodies) antagonist action in rescuing exhausted CTLs in chronic infection.

  8. Upon miR (show MLXIP Antibodies)-155 overexpression, Cd40 expression was significantly upregulated with a negative correlation to the miR (show MLXIP Antibodies)-155 primary target Ship1 (show INPP5D Antibodies) expression in mice.

  9. These results suggest that Il23a (show IL23A Antibodies) expression in DCs is synergistically triggered by the PG E2-EP4 (show PTGER4 Antibodies)-cAMP-PKA pathway and canonical/non-canonical NF-kappaB (show NFKB1 Antibodies) pathways and CREB (show CREB1 Antibodies) activated by CD40 stimulation.

  10. Results suggest that altered CD40 signaling and granulocyte recruitment in response to infection are responsible for the Ity5-associated Salmonella susceptibility of A/J mice.

Human CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

  1. CD40 signaling in adipose tissue macrophages regulates major histocompatibility complex class II and CD86 (show CD86 Antibodies) expression to control the expansion of CD4 (show CD4 Antibodies)(+) T cells.

  2. CD40 activation resulted in down-regulation of Thioredoxin (Trx)-1 (show TXN Antibodies) to permit ASK1 (show MAP3K5 Antibodies) activation and apoptosis. Although soluble receptor (show IFNAR1 Antibodies) agonist alone could not induce death, combinatorial treatment incorporating soluble CD40 agonist and pharmacological inhibition of Trx-1 (show MLL Antibodies) was functionally equivalent to the signal triggered by mCD40L.

  3. autologous CD4 (show CD4 Antibodies)(+) T cells that are exposed to EVs from CD40/IL-4 (show IL4 Antibodies)-stimulated CLL cells exhibit enhanced migration, immunological synapse signaling, and interactions with tumor cells.

  4. Cytokine expression upon simultaneous stimulation of TSHR and CD40 is greater than levels achieved with TSH or CD40L alone. Increased expression of CD40 by TSH is a potential mechanism for this process

  5. glatiramer acetate treatment also significantly reduced CD40-mediated P65 (show GORASP1 Antibodies) phosphorylation in RRMS patients, suggesting that reducing CD40-mediated p-P65 (show GORASP1 Antibodies) induction may be a general mechanism by which some current therapies modulate Multiple Sclerosis disease.

  6. Circulating sCD40L levels are increased in patients with cystic fibrosis (show S100A8 Antibodies) and P. aeruginosa infection

  7. Our results support an important association of rs4810485 in CD40 gene and rs763361 in CD226 (show CD226 Antibodies) gene polymorphism, combined effect of rs4810485 and rs763361 with increased risk of systemic lupus erythematosus.

  8. CD40 activity in thyrocytes is prominently mediated via NF-kappaB (show NFKB1 Antibodies).

  9. polymorphisms in the TP63 and CD40 genes are associated with lung cancer in a Chinese Han population

  10. Increased CD40 ligation and reduced B-cell receptor signalling leads to higher IL-10 (show IL10 Antibodies) production in B Cells from tolerant kidney transplant recipients.

Pig (Porcine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

  1. These results therefore may help understand the molecular mechanism of CD40L (show CD40LG Antibodies) signaling that contributes to the pathophysiology of atherosclerosis.

  2. This study shows that xenogeneic interaction between hCD40L and pCD40 can activate porcine endothelial cells through NF-kappaB (show NFKB1 Antibodies) signaling.

  3. The appearance of CD25 (show IL2RA Antibodies) after activation of porcine dendritic cells, is reported.

Cow (Bovine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

  1. Results demonstrated greater CD40 and CD40L (show CD40LG Antibodies) expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.

  2. study investigated the hypothesis that CD40 signalling is impaired in Mycobacterium avium subspecies paratuberculosis-infected macrophages

CD40 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with CD40

  • CD40 antigen (LOC100349106) antibody
  • CD40 antigen (Cd40) antibody
  • CD40 molecule, TNF receptor superfamily member 5 (CD40) antibody
  • CD40 molecule, TNF receptor superfamily member 5 (Cd40) antibody
  • dynactin 2 (Dctn2) antibody
  • 2310042E05Rik antibody
  • AI326936 antibody
  • Bp50 antibody
  • C87049 antibody
  • C130077D06Rik antibody
  • CDW40 antibody
  • DCTN-50 antibody
  • GMP23-48K antibody
  • GP39 antibody
  • HIGM1 antibody
  • IGM antibody
  • IMD3 antibody
  • p50 antibody
  • RBP50 antibody
  • T-BAM antibody
  • TNFRSF5 antibody
  • TNFSF5 antibody
  • TRAP antibody

Protein level used designations for CD40

B-cell surface antigen CD40 , CD40L receptor , T-cell differentiation antigen , tumor necrosis factor receptor superfamily member 5 , tumor necrosis factor receptor superfamily, member 5 , B cell surface antigen CD40 , B cell-associated molecule , CD40 antigen (TNF receptor superfamily member 5) , CD40 type II isoform , nerve growth factor receptor-related B-lymphocyte activation molecule , CD40 antigen, TNF receptor superfamily member 5 , human CD40-homologue , 50 kDa dynein-associated polypeptide , dynactin complex 50 kDa subunit , dynactin subunit 2 , growth cone membrane protein 23-48K , p50 dynamitin

GENE ID SPECIES
100349106 Oryctolagus cuniculus
21939 Mus musculus
958 Homo sapiens
397395 Sus scrofa
171369 Rattus norvegicus
286849 Bos taurus
395385 Gallus gallus
403469 Canis lupus familiaris
100034049 Equus caballus
100385800 Callithrix jacchus
69654 Mus musculus
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