Browse our IL1R2 Proteins (IL1R2)

Full name:
Interleukin 1 Receptor, Type II Proteins (IL1R2)
On are 27 Interleukin 1 Receptor, Type II (IL1R2) Proteins from 9 different suppliers available. Additionally we are shipping IL1R2 Antibodies (141) and IL1R2 Kits (39) and many more products for this protein. A total of 227 IL1R2 products are currently listed.
CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, Il1r-2, IL1R2c, IL1RB
list all proteins Gene Name GeneID UniProt
IL1R2 7850 P27930
IL1R2 16178 P27931
IL1R2 117022 P43303

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IL1R2 Proteins (IL1R2) by Origin

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Top referenced IL1R2 Proteins

  1. Human IL1R2 Protein expressed in HEK-293 Cells - ABIN2181359 : Liu, Hart, Liu, Clevenger, Maki, De Souza: Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA. in The Journal of biological chemistry 1996 (PubMed)
    Show all 7 references for 2181359

  2. Cynomolgus IL1R2 Protein expressed in Human Cells - ABIN2009880 : Colotta, Re, Muzio, Bertini, Polentarutti, Sironi, Giri, Dower, Sims, Mantovani: Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. in Science (New York, N.Y.) 1993 (PubMed)
    Show all 5 references for 2009880

  3. Mouse (Murine) IL1R2 Protein expressed in Human Cells - ABIN2008586 : McMahan, Slack, Mosley, Cosman, Lupton, Brunton, Grubin, Wignall, Jenkins, Brannan: A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. in The EMBO journal 1991 (PubMed)
    Show all 5 references for 2008586

  4. Rat (Rattus) IL1R2 Protein expressed in Human Cells - ABIN2009286 : Rauschmayr, Groves, Kupper: Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 5 references for 2009286

  5. Dog (Canine) IL1R2 Protein expressed in Human Cells - ABIN2008958 : Neumann, Kollewe, Martin, Boraschi: The membrane form of the type II IL-1 receptor accounts for inhibitory function. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 5 references for 2008958

More Proteins for IL1R2 Interaction Partners

Human Interleukin 1 Receptor, Type II (IL1R2) interaction partners

  1. Expression level of IL1R2 was down regulated in cervical squamous cell carcinoma.

  2. No significant differences in the lymphocyte mRNA levels of IL-1R2, IL-6R, and Gp130 (show IL6ST Proteins) were observed between MDD patients and NC. These studies suggest abnormal gene expression of these cytokines and their membrane-bound receptors in the lymphocytes of MDD patients, and that their mRNA expression levels in the lymphocytes could be a useful biomarker for depression.

  3. IL1R2 rs2310173 genotype GT was mildly protective against ankylosing spontylitis only in HLA-B27-negative patients.

  4. IL1R2 hypomethylation and androgen receptor (show AR Proteins) hypermethylation may constitute an important determinant of disease severity, whereas NPR2 (show NPRL2 Proteins) hypomethylation and SP140 (show SP140 Proteins) hypermethylation may provide a biomarker for vulnerability to excessive daytime sleepiness in Obstructive Sleep Apnea

  5. This is the first detection that the genetic variation rs2302589 in IL-1R2 gene was associated with ankylosing spondylitis in Northern Han Chinese.

  6. Data show that interleukin-1 receptor type 2 (IL1R2) forms a complex with c-Fos proto-oncogene protein and activates the interleukin-6 (IL-6 (show IL6 Proteins)) and vascular endothelial growth factor A (VEGF-A (show VEGFA Proteins)) promoters.

  7. Cerebrospinal fluid soluble interleukin-1 Receptor II, but not log interleukin-6 (show IL6 Proteins), levels were positively correlated with a composite measure of aggression.

  8. results suggested that IL1R2 could have oncogenic potential in osteosarcoma

  9. Interleukin-1alpha Activity in Necrotic Endothelial Cells Is Controlled by Caspase-1 (show CASP1 Proteins) Cleavage of Interleukin-1 Receptor-2 (show IL1RL2 Proteins)

  10. A genetic susceptibility locus for AgP may lie within or close to the IL1R2 locus in Japanese aggressive periodontitis.

Mouse (Murine) Interleukin 1 Receptor, Type II (IL1R2) interaction partners

  1. Data indicate that a disintegrin and metallopeptidase domain 17 (ADAM17 (show ADAM17 Proteins)) regulates interleukin (IL)-1 (show IL1A Proteins) signaling via cleavage of IL-1 (show IL1A Proteins) receptor type 2 (IL-1R2).

  2. IL-1 (show IL1A Proteins) receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 (show IL1A Proteins) signal on macrophages.

  3. Interleukin-1 receptor type II is significantly upregulated in decidual cells close to the embryo during days 5 to 8 of pregnancy.

  4. Data show that bee venom detected by inflammasome and trigger activation of caspase-1 (show CASP1 Proteins) and secretion of proinflammatory cytokine IL-1beta (show IL1B Proteins) is pyrin domain-containing 3 NLRP3 (show NLRP3 Proteins), apoptosis-associated speck-like protein ASC (show STS Proteins), and IL-1 (show IL1A Proteins) receptor dependent.

  5. inoculation of young CD4 (show CD4 Proteins)(+) T cells or a fetal thymus graft led to down regulation of the interleukin 1 receptor type II (IL-1R2) gene in CD4 (show CD4 Proteins)(+) T cells and reduced age-related hearing loss

  6. BACE1 (show BACE Proteins) and BACE2 (show BACE2 Proteins) may act as alternative alpha-secretase-like proteases in proteolytic processing of IL-1R2 and APP (show APP Proteins)

IL1R2 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Alternative names and synonyms associated with IL1R2

  • interleukin 1 receptor, type II (IL1R2)
  • interleukin 1 receptor, type II (Il1r2)
  • CD121b protein
  • CDw121b protein
  • IL-1R-2 protein
  • IL-1RT-2 protein
  • IL-1RT2 protein
  • Il1r-2 protein
  • IL1R2c protein
  • IL1RB protein

Protein level used designations for IL1R2

interleukin-1 receptor type 2 , soluble type II IL-1 receptor , CD121 antigen-like family member B , IL-1 type II receptor , IL-1R-beta , antigen CDw121b , interleukin 1 receptor type II variant 3 , interleukin-1 receptor beta , interleukin-1 receptor type II , type II interleukin-1 receptor, beta , IL-1 receptor beta chain , IL-1R-2 , IL-1RT-2 , IL-1RT2

711638 Macaca mulatta
7850 Homo sapiens
16178 Mus musculus
481330 Canis lupus familiaris
117022 Rattus norvegicus
100628112 Sus scrofa
418715 Gallus gallus
100723930 Cavia porcellus
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