Browse our IL1RAP Proteins (IL1RAP)

Full name:
Interleukin 1 Receptor Accessory Protein Proteins (IL1RAP)
On are 26 Interleukin 1 Receptor Accessory Protein (IL1RAP) Proteins from 9 different suppliers available. Additionally we are shipping IL1RAP Antibodies (78) and IL1RAP Kits (27) and many more products for this protein. A total of 143 IL1RAP products are currently listed.
6430709H04Rik, AI255955, AV239853, C3orf13, IL-1RAcp, il-racp, IL1R3, Il1racpb, IL1RAP
list all proteins Gene Name GeneID UniProt
IL1RAP 3556 Q9NPH3
IL1RAP 16180 Q61730
Rat IL1RAP IL1RAP 25466 Q63621

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IL1RAP Proteins (IL1RAP) by Origin

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Top referenced IL1RAP Proteins

  1. Human IL1RAP Protein expressed in Human Cells - ABIN2002117 : Smith, Hanna, Della Friend, Moore, Chen, Farese, MacVittie, Virca, Sims: The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. in Immunity 2003 (PubMed)
    Show all 6 references for 2002117

  2. Human IL1RAP Protein expressed in Human Cells - ABIN2002119 : Huang, Gao, Li, Cao: Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 6 references for 2002119

  3. Human IL1RAP Protein expressed in HEK-293 Cells - ABIN2749236 : Worm, Jensen, Hansen, Søndergaard, Nybroe: Interactions between proteolytic and non-proteolytic Pseudomonas fluorescens affect protein degradation in a model community. in FEMS microbiology ecology 2000 (PubMed)
    Show all 4 references for 2749236

More Proteins for IL1RAP Interaction Partners

Pig (Porcine) Interleukin 1 Receptor Accessory Protein (IL1RAP) interaction partners

  1. IL1B (show IL1B Proteins) regulates expression of IL1R1 (show IL1RN Proteins) and IL1RAP and stimulates expression of PTGS1 (show PTGS1 Proteins) and PTGS2 (show PTGS2 Proteins) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Proteins)-implantation period of pregnancy in pigs.

Human Interleukin 1 Receptor Accessory Protein (IL1RAP) interaction partners

  1. These results provide novel insights into the role of IL1RAP in CML and a strong rationale for the development of an IL1RAP antibody therapy to target residual CML stem cells.

  2. single nucleotide polymorphism A471T in the Toll (show TLR4 Proteins)-interleukin 1 receptor domain (TIR) of the IL-1Rrp2 (show IL1RL2 Proteins) that is present in approximately 2% of the human population, down-regulated IL-36R (show IL1RL2 Proteins) signaling by a decrease of interaction with IL-1RAcP.

  3. The findings of this study support IL1RAP as a novel potential Alzheimer's disease target and highlight the use of amyloid PET as a valuable Alzheimer's disease endophenotype, particularly in a longitudinal framework.

  4. The SNP rs4624606 in IL-1RAcP was nominally associated with CAD risk.

  5. Data suggest serum levels of soluble IL1RAP (from alternative splicing) are down-regulated in endometriosis throughout menstrual cycle; IL1RAP levels (which peak in proliferative phase in fertile women) exhibit minor variations in endometriosis.

  6. Combined crystallography and small-angle X-ray-scattering studies reveal that ST2 (show SULT2A1 Proteins) possesses hinge flexibility between the D3 domain and D1D2 module, whereas IL-1RAcP exhibits a rigid conformation in the unbound state in solution.

  7. MARCH8 (show MARCH8 Proteins)-mediated polyubiquitination and degradation of IL1RAP is an important mechanism for negative regulation of IL-1beta (show IL1B Proteins)-induced signaling pathways.

  8. Knockdown of IL1RAP decreased clonogenicity and increased cell death of AML (show RUNX1 Proteins) cells.

  9. Interleukin-1R3 mediates interleukin-1-induced potassium current increase through fast activation of Akt (show AKT1 Proteins) kinase.

  10. The genetic polymorphisms of IL-1ss-2023 C allele, IL- 1RAcP -8261 T allele and -8183 A allele are probable host factors for persistent HBV infection.

Mouse (Murine) Interleukin 1 Receptor Accessory Protein (IL1RAP) interaction partners

  1. These results thus reveal the decoding mechanism of splice-insert signaling codes for synaptic differentiation induced by trans-synaptic adhesion between PTPdelta and IL1RAPL1 (show IL1RAPL1 Proteins)/IL-1RAcP.

  2. In experimental biliary atresia, miR (show MLXIP Proteins)-29a/29b1 are upregulated, and reporter assays confirmed that Igf1 (show IGF1 Proteins) and Il1RAP are down-regulated by miR (show MLXIP Proteins)-29.

  3. The results of this study suggested that IL-1RAcP represents an interesting molecular link between immune systems and synapse formation in the brain.

  4. IL-1RAcP is essential for physiological activities of peripheral IL-1 (show IL1A Proteins).

  5. Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling

  6. data suggest that domain III of IL-1RAcP may be involved in the formation or stabilization of the IL-1RI/IL-1 (show IL1A Proteins) complex by binding to epitopes on domain III of the IL-1RI created following IL-1 (show IL1A Proteins) binding to the IL-1RI

  7. IL-33 (show IL33 Proteins) and ST2 (show SULT2A1 Proteins) form a complex with IL-1R accessory protein (IL-1RAcP), a signaling receptor subunit that is also a member of the IL-1R complex.

  8. IL-1RAcP is used by more than one alpha-chain (show FCGRT Proteins) of the IL-1 (show IL1A Proteins) receptor family and thus may resemble a common beta-chain (show CSF2RB Proteins) of that family

  9. these observations establish AcP (show NDUFAB1 Proteins) as co-receptor for IL-33 (show IL33 Proteins) signaling via ST2 (show SULT2A1 Proteins) and suggest a novel role for sAcP in modulating the biological activity of IL-33 (show IL33 Proteins)

  10. an isoform of the IL-1 receptor accessory protein (termed AcPb) was identified that is expressed exclusively in the CNS.

IL1RAP Protein Profile

Protein Summary

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Alternative names and synonyms associated with IL1RAP

  • interleukin 1 receptor accessory protein (IL1RAP)
  • interleukin 1 receptor accessory protein (il1rap)
  • interleukin 1 receptor accessory protein (il-1racp)
  • interleukin 1 receptor accessory protein (Il1rap)
  • 6430709H04Rik protein
  • AI255955 protein
  • AV239853 protein
  • C3orf13 protein
  • IL-1RAcp protein
  • il-racp protein
  • IL1R3 protein
  • Il1racpb protein
  • IL1RAP protein

Protein level used designations for IL1RAP

interleukin 1 receptor accessory protein , interleukin-1 receptor accessory protein , interleukin-1 receptor accessory protein-like , IL-1 receptor accessory protein , IL-1R3 , interleukin-1 receptor 3 , interleukin-1 receptor accessory protein beta , IL-1RAcP

424908 Gallus gallus
460935 Pan troglodytes
488126 Canis lupus familiaris
539334 Bos taurus
100068726 Equus caballus
100172432 Pongo abelii
100216065 Xenopus (Silurana) tropicalis
100392625 Callithrix jacchus
100472192 Ailuropoda melanoleuca
100016835 Monodelphis domestica
100341281 Oryctolagus cuniculus
100580986 Nomascus leucogenys
100628318 Sus scrofa
100136401 Salmo salar
3556 Homo sapiens
16180 Mus musculus
25466 Rattus norvegicus
574387 Macaca mulatta
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