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Browse our IL1RN Proteins (IL1RN)

Full name:
Interleukin 1 Receptor Antagonist Proteins (IL1RN)
On are 74 Interleukin 1 Receptor Antagonist (IL1RN) Proteins from 17 different suppliers available. Additionally we are shipping IL1RN Antibodies (228) and IL1RN Kits (90) and many more products for this protein. A total of 408 IL1RN products are currently listed.
DIRA, F630041P17Rik, icIL-1ra, IL-1RA, IL-1ra3, IL-1RN, IL1F3, IL1RA, IL1RN, IRAP, IRAP1, MVCD4
list all proteins Gene Name GeneID UniProt
IL1RN 3557 P18510
IL1RN 60582 P25086
IL1RN 16181 P25085

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IL1RN Proteins (IL1RN) by Origin

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Top referenced IL1RN Proteins

  1. Human IL1RN Protein expressed in Escherichia coli (E. coli) - ABIN2666839 : Arend: The balance between IL-1 and IL-1Ra in disease. in Cytokine & growth factor reviews 2002 (PubMed)
    Show all 5 references for ABIN2666839

  2. Rat (Rattus) IL1RN Protein expressed in Human Cells - ABIN2009118 : Haskill, Martin, Van Le, Morris, Peace, Bigler, Jaffe, Hammerberg, Sporn, Fong: cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN2009118

  3. Human IL1RN Protein expressed in Human Cells - ABIN2002122 : Sehouli, Mustea, Könsgen, Katsares, Lichtenegger: Polymorphism of IL-1 receptor antagonist gene: role in cancer. in Anticancer research 2003 (PubMed)
    Show all 4 references for ABIN2002122

  4. Human IL1RN Protein expressed in Escherichia coli (E. coli) - ABIN2002123 : Arend, Malyak, Guthridge, Gabay: Interleukin-1 receptor antagonist: role in biology. in Annual review of immunology 1998 (PubMed)
    Show all 4 references for ABIN2002123

  5. Human IL1RN Protein expressed in Escherichia coli (E. coli) - ABIN2667496 : Zhang, Liu, Peng, Zhang, Feng: IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: a literature review and meta-analysis. in PLoS ONE 2012 (PubMed)
    Show all 3 references for ABIN2667496

  6. Mouse (Murine) IL1RN Protein expressed in Escherichia coli (E. coli) - ABIN1098264 : Steinkasserer, Spurr, Cox, Jeggo, Sim: The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci. in Genomics 1992 (PubMed)

More Proteins for IL1RN Interaction Partners

Human Interleukin 1 Receptor Antagonist (IL1RN) interaction partners

  1. Results show that the presence of IL-1b (show IL1B Proteins) and IL-1RN polymorphisms with Helicobacter pylori infection of the gastric mucosa contributes to the development of gastric carcinoma in an Algerian population.

  2. this study shows that IL-1Ra gene variants are associated with susceptibility to juvenile idiopathic arthritis in Iranian population

  3. The A2 allele of the interleukin 1 receptor antagonist VNTR polymorphism could be a protective factor for pre-eclampsia susceptibility.

  4. There were no significant differences between patients with Behcet's disease and controls with respect to the IL-1Ra, IL-1beta (show IL1B Proteins), IL-2 (show IL2 Proteins), IL-6 (show IL6 Proteins) and the IL-10 (show IL10 Proteins) gene polymorphism distributions. Correlations between the articular involvement and IL-1RN, the ocular involvement and the IL-1beta (show IL1B Proteins), and the age of disease onset and the IL-2 (show IL2 Proteins) and IL-10 (show IL10 Proteins) polymorphisms suggest that that they could be associated with disease symptoms.

  5. A2 allele and the combined IL-4 (show IL4 Proteins) (low) -IL-1Ra (high) genotype might be genetic markers of susceptibility to frailty in Mexican elderly.

  6. This study demonstrated that thr (show TRH Proteins) frequency of the IL-1Ra/C allele at position Mspa-I 11100 was decreased significantly and the IL-1Ra/T frequency was significantly increased in patients with Febrile Seizures.

  7. Data indicate that levels of interleukin 1 receptor antagonist protein (IL-1 (show IL1A Proteins)-Ra) remain elevated for at least one year after storage at -80 degrees C.

  8. study showed that, IL-1RN allele 2, periodontal disease characterized with clinical attachment loss, previous preterm/low birth weight outcome (PLBW) and age could be important risk factors for PLBW

  9. Significant associations were found between Crohn's disease (CD) and minor NOD2 variants, as well as TLR4 (show TLR4 Proteins) 299Gly, TNF-alpha (show TNF Proteins) G-308A, IL-6 (show IL6 Proteins) G-174C and IL-1RN VNTR A2 variants, while ulcerative colitis (UC) was associated only with IL-1RN VNTR A2 variants.

  10. Suggest that IL-1RN rs315952 polymorphism may not be associated with susceptibility to Tourette syndrome in Chinese Han population.

Mouse (Murine) Interleukin 1 Receptor Antagonist (IL1RN) interaction partners

  1. we demonstrate that the release of IL1RA in response to genotoxic stress contributes to the immunosuppressive effects of apoptotic cells.

  2. results provide evidence of the key role of IL1RA secreted by MSCs to both control the polarization of macrophages toward a M2 phenotype and inhibit B cell differentiation in vivo.

  3. Allo-transplantation of mesenchymal stem cells reduces Con (show KITLG Proteins) A liver injury by increasing IL10 (show IL10 Proteins) production through an IL1Ra dependent macrophage switch.

  4. results demonstrate that small intestinal eosinophils play a pivotal role in the maintenance of intestinal homeostasis by regulating Th17 cells via production of IL-1Ra.

  5. While both contributing to pathogen clearance, NLRP3 (show NLRP3 Proteins) more than NLRC4 (show NLRC4 Proteins) contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 Proteins) and correlates with defective NLRC4 (show NLRC4 Proteins)-dependent IL-1Ra production.

  6. IL-1Ra deficiencies might promote early plaque development in 16-week-old apoE (show APOE Proteins)(-/-) mice.

  7. IL-1Ra is associated with MMP-13 (show MMP13 Proteins) expression and has a novel function in such regulation without interference of the IL-1 (show IL1A Proteins) signaling cascade.

  8. These findings demonstrated novel roles for F-spondin (show SPON1 Proteins) and IL-1Ra in type B CpG oligodeoxynucleotides-mediated cell proliferation and migration of macrophages.

  9. Leading to enhanced interleukin-1 receptor antagonist (IL-1RA) production.

  10. Results suggest that the IL-1R1/IL-1ra complex regulates specific ethanol behaviors and affects the sensitivity to flurazepam sedation

Rabbit Interleukin 1 Receptor Antagonist (IL1RN) interaction partners

  1. IL-8 (show IL8 Proteins) and IL-1ra showed correlation with the severity of colitis. These observations should significantly further understandings on the role of neutrophils and monocytes in the immunopathogenesis of ulcerative colitis

Horse (Equine) Interleukin 1 Receptor Antagonist (IL1RN) interaction partners

  1. Expression of IL-1RN in the endometrium is likely regulated by estradiol and progesterone and suggest that IL-1RN regulates the degree of IL-1 (show IL1A Proteins) signal transduction and thereby plays an important role in the establishment of equine pregnancy.

Rhesus Monkey Interleukin 1 Receptor Antagonist (IL1RN) interaction partners

  1. The variable number of tandem repeats polymorphism in the IL-1RN gene may be a useful predictor of negative symptom improvement in schizophrenic patients treated with antipsychotic drugs.

  2. common variation across the IL-1RN gene is strongly associated with IL-1RA levels.

IL1RN Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with IL1RN

  • interleukin 1 receptor antagonist (IL1RN)
  • interleukin 1 receptor antagonist (Il1rn)
  • interleukin 1 receptor, type I (IL1R1)
  • DIRA protein
  • F630041P17Rik protein
  • icIL-1ra protein
  • IL-1RA protein
  • IL-1ra3 protein
  • IL-1RN protein
  • IL1F3 protein
  • IL1RA protein
  • IL1RN protein
  • IRAP protein
  • IRAP1 protein
  • MVCD4 protein

Protein level used designations for IL1RN

interleukin 1 receptor antagonist , IL1 inhibitor , IL1RN (IL1F3) , interleukin-1 receptor antagonist protein , intracellular IL-1 receptor antagonist type II , intracellular interleukin-1 receptor antagonist (icIL-1ra) , type II interleukin-1 receptor antagonist , IL-1RN , IL-1ra , IRAP , interleukin-1 receptor antagonist intracellular form , interleukin-1 receptor antagonist secretory form , secretory interleukin-1 receptor antagonist

459501 Pan troglodytes
3557 Homo sapiens
397499 Sus scrofa
60582 Rattus norvegicus
16181 Mus musculus
281860 Bos taurus
403660 Canis lupus familiaris
100301539 Oryctolagus cuniculus
100034236 Equus caballus
100721865 Cavia porcellus
100861585 Gallus gallus
701658 Macaca mulatta
100009558 Oryctolagus cuniculus
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