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Browse our anti-KHDRBS1 (KHDRBS1) Antibodies

Full name:
anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 Antibodies (KHDRBS1)
On www.antibodies-online.com are 122 KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Antibodies from 19 different suppliers available. Additionally we are shipping KHDRBS1 Proteins (11) and KHDRBS1 Kits (9) and many more products for this protein. A total of 148 KHDRBS1 products are currently listed.
Synonyms:
A170, fj90g10, KHDRBS1, OSIL, p60, P62, p62B, p68, PDB3, Sam68, wu:fa18g12, wu:fa56c01, wu:fc91b01, wu:fj90g10, zgc:113899, ZIP3
list all antibodies Gene Name GeneID UniProt
KHDRBS1 10657 Q07666
KHDRBS1 20218 Q60749
KHDRBS1 117268 Q91V33

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Most Popular Reactivities for anti-KHDRBS1 (KHDRBS1) Antibodies

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anti-Human KHDRBS1 Antibodies:

anti-Mouse (Murine) KHDRBS1 Antibodies:

anti-Rat (Rattus) KHDRBS1 Antibodies:

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Top referenced anti-KHDRBS1 Antibodies

  1. Human Polyclonal KHDRBS1 Primary Antibody for ICC, IF - ABIN4351941 : Lawrence, Schafer, Rieder: The nuclear protein Sam68 is cleaved by the FMDV 3C protease redistributing Sam68 to the cytoplasm during FMDV infection of host cells. in Virology 2012 (PubMed)
    Show all 2 references for ABIN4351941

  2. Cow (Bovine) Polyclonal KHDRBS1 Primary Antibody for IHC, WB - ABIN2778999 : Duran, Linares, Galvez, Wikenheiser, Flores, Diaz-Meco, Moscat: The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. in Cancer cell 2008 (PubMed)

  3. Human Polyclonal KHDRBS1 Primary Antibody for EIA, IHC (fro) - ABIN1108931 : Grange, Belly, Dupas, Trembleau, Sadoul, Goldberg: Specific interaction between Sam68 and neuronal mRNAs: implication for the activity-dependent biosynthesis of elongation factor eEF1A. in Journal of neuroscience research 2008 (PubMed)

  4. Cow (Bovine) Polyclonal KHDRBS1 Primary Antibody for WB - ABIN2779966 : Paronetto, Zalfa, Botti, Geremia, Bagni, Sette: The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes. in Molecular biology of the cell 2005 (PubMed)

More Antibodies against KHDRBS1 Interaction Partners

Human KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) interaction partners

  1. Sam68 is essential for DNA damage-induced NF-kappaB (show NFKB1 Antibodies) activation and colon tumorigenesis.

  2. These findings define a hitherto novel mechanism of action for Sam68 in governing p53 (show TP53 Antibodies) transcriptional activation, and represent the first report of Sam68 in the regulation of tumor suppressor activities.

  3. HNRNPL (show HNRNPL Antibodies) acts as the adaptor to combine the two substructures and form the intact Sam68 nuclear body through the interaction of two sets of RNA recognition motifs with the putative architectural RNA in the respective substructures.

  4. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  5. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  6. Sam68 was overexpressed in EOC tissue in association with such cancer malignant factors of FIGO stage, histological grade, and lymph node metastasis, and also positively regulated the proliferation of EOC cells.

  7. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  8. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

  9. findings expand the SQSTM1 (show SQSTM1 Antibodies)-associated phenotypic spectrum and lend further support to the concept of disturbed selective autophagy pathways in neurodegenerative diseases

  10. Aldo was revealed to induce autophagy, as indicated by the increased conversion from microtubuleassociated protein 1A/1Blight chain 3 (LC3)I to LC3II, the increased expression levels of autophagyrelated gene 7 (Atg7) and the increased degradation of p62, which was accompanied by MC proliferation

Mouse (Murine) KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) interaction partners

  1. Sam68 is essential for DNA damage-induced NF-kappaB (show NFKB1 Antibodies) activation and colon tumorigenesis.

  2. Sam68 and T-STAR (show KHDRBS3 Antibodies) could regulate alternative splicing of some pre-mRNAs by bringing two distant UAA motifs into proximity and looping out regions of the pre-mRNA.

  3. SAM68 is a physiological regulator of SMN2 (show SMN1 Antibodies) splicing in a spinal muscular atrophy mouse model.

  4. Data (including data from knockout mice) suggest expression of Sam68 plays role in adipogenesis of white adipose tissue versus brown adipose tissue; Sam68 appears to regulate adiposity and energy homeostasis (balance of energy intake/expenditure).

  5. Depletion of p31S6K1 with small interfering RNAs (siRNAs) partially restored adipogenesis of Sam68-deficient preadipocytes.

  6. Emerging roles for Sam68 in adipogenesis and neuronal development.

  7. Our research identifies a role for Sam68 in synaptodendritic posttranscriptional regulation of actb (show ACTB Antibodies) and may provide insight into the pathophysiology of fragile X (show FMR1 Antibodies) tremor/ataxia (show USP14 Antibodies) syndrome

  8. Results suggest a novel role for SAM68 in the miRNA pathway during spermatogenesis.

  9. Sam68 regulates alternative splicing during adipogenesis.

  10. We demonstrated that the FMDV 3C(pro) induced the cleavage of nuclear RNA-binding protein Sam68 C-terminus containing the nuclear localization sequence (NLS (show ALDH1A2 Antibodies) and stimulated the redistribution of Sam68 to the cytoplasm.

KHDRBS1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with KHDRBS1

  • KH domain containing, RNA binding, signal transduction associated 1a (khdrbs1a) antibody
  • KH domain containing, RNA binding, signal transduction associated 1 (KHDRBS1) antibody
  • KH domain containing, RNA binding, signal transduction associated 1 (khdrbs1) antibody
  • KH domain containing, RNA binding, signal transduction associated 1 (Khdrbs1) antibody
  • sequestosome 1 (SQSTM1) antibody
  • A170 antibody
  • fj90g10 antibody
  • KHDRBS1 antibody
  • OSIL antibody
  • p60 antibody
  • P62 antibody
  • p62B antibody
  • p68 antibody
  • PDB3 antibody
  • Sam68 antibody
  • wu:fa18g12 antibody
  • wu:fa56c01 antibody
  • wu:fc91b01 antibody
  • wu:fj90g10 antibody
  • zgc:113899 antibody
  • ZIP3 antibody

Protein level used designations for KHDRBS1

GAP-associated phosphoprotein p62 , KH domain containing, RNA binding, signal transduction associated 1 , fa18g12 , fa56c01 , fc91b01 , GAP-associated tyrosine phosphoprotein p62 (Sam68) , KH domain-containing, RNA-binding, signal transduction-associated protein 1 , p21 Ras GTPase-activating protein-associated p62 , src-associated in mitosis 68 kDa protein , GAP-associated tyrosine phosphoprotein p62 , src associated in mitosis, 68 kDa , p68 , KH domain RNA-binding protein Sam68 , sam68 , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , sequestosome-1 , ubiquitin-binding protein p62

GENE ID SPECIES
30082 Danio rerio
456705 Pan troglodytes
487316 Canis lupus familiaris
549799 Xenopus (Silurana) tropicalis
100025483 Monodelphis domestica
10657 Homo sapiens
538775 Bos taurus
20218 Mus musculus
117268 Rattus norvegicus
398660 Xenopus laevis
374071 Gallus gallus
8878 Homo sapiens
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