You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our p65 Proteins (NFkBP65)

Full name:
Nuclear Factor-KB P65 Proteins (NFkBP65)
On www.antibodies-online.com are 19 Nuclear Factor-KB P65 (NFkBP65) Proteins from 8 different suppliers available. Additionally we are shipping p65 Antibodies (1162) and p65 Kits (98) and many more products for this protein. A total of 1343 p65 products are currently listed.
Synonyms:
NFkB, NFKB3, p65
list all proteins Gene Name GeneID UniProt
NFkBP65 5970 Q04206
Rat NFkBP65 NFkBP65 309165  
NFkBP65 19697 Q04207

Show all synonyms

p65 Proteins (NFkBP65) by Origin

Select your origin of interest

Top referenced p65 Proteins

  1. Human p65 Protein expressed in HEK-293 Cells - ABIN2730698 : Srinivasan, Blackburn, Lahiri: Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation. in Drug design, development and therapy 2015 (PubMed)
    Show all 5 references for ABIN2730698

  2. Human p65 Protein expressed in Wheat germ - ABIN1317783 : Ba, Bacsi, Luo, Aguilera-Aguirre, Zeng, Radak, Brasier, Boldogh: 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Proteins for p65 Interaction Partners

Human Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. RNA and protein expressions of NF-kappaB (show NFKB1 Proteins) and STAT3 (show STAT3 Proteins) increased significantly in thyroid carcinoma tissues.

  2. showed that NF-KBp50, p65 (show GORASP1 Proteins) and HIF1a (show HIF1A Proteins) form higher order heteromultimeric complexes overlapping rs7901656, implying synergism of action among TFs governing cellular response to infection and hypoxia

  3. our results demonstrate that miR (show MLXIP Proteins)-200b, a transcriptional target of NF-kappaB (show NFKB1 Proteins), suppresses breast cancer cell growth and migration, and NF-kappaB (show NFKB1 Proteins) activation, through downregulation of IKBKB (show IKBKB Proteins), indicating that miR (show MLXIP Proteins)-200b has potential as a therapeutic target in breast cancer patients.

  4. Nuclear translocation of NFkappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) was confirmed for synchronous and asynchronous conditions in the presence of flow reversal. These data suggest that asynchronous hemodynamics and reversing flow can elicit proatherogenic responses in endothelial cells compared to synchronous hemodynamics without shear stress reversal, indicating that SPA (show FASL Proteins) as well as reversal flow (OSI (show SQSTM1 Proteins)) are important parameters characterizing arteria...

  5. TPD52 directly interacts with nuclear factor-kappaB p65 (RelA) and promotes accumulation of phosphorylated nuclear factor-kappaB (p65 (show GORASP1 Proteins))(S536) that is directly linked with nuclear factor-kappaB transactivation

  6. elevation of O-GlcNAcylation by overexpression of OGT (show OGT Proteins) increased the expression of p300 (show EP300 Proteins), IKKalpha (show CHUK Proteins), and IKKbeta (show IKBKB Proteins) and promoted IKK (show CHUK Proteins)-mediated activating phosphorylation of p65 (show GORASP1 Proteins) at Ser (show SIGLEC1 Proteins)-536, contributing to NF-kappaB (show NFKB1 Proteins) activation. In addition, we also identified phosphorylation of p65 (show GORASP1 Proteins) at Thr (show TRH Proteins)-308, which might impair the O-GlcNAcylation of p65 (show GORASP1 Proteins) at Thr (show TRH Proteins)-305.

  7. Furthermore, employing the human macrophage-like cell line U937 we observed comparable results with NF-kappaB (show NFKB1 Proteins)/p65 (show GORASP1 Proteins) down-regulation and we also observed a significant reduction in the IL-6 (show IL6 Proteins) and TNF-alpha (show TNF Proteins) mRNA, as well as in their secreted pro-inflammatory cytokines following miR (show MLXIP Proteins)-138 expression, suggesting that canonical NF-kappaB (show NFKB1 Proteins) target genes might also be potential targets for miR (show MLXIP Proteins)-138 in leukemia cells.

  8. UL24 was demonstrated to inhibit the activation of NF-kappaB (show NFKB1 Proteins) in the DNA sensing signal pathway via binding to the Rel homology domains of the NF-kappaB (show NFKB1 Proteins) subunits p65 (show GORASP1 Proteins) and p50 (show CD40 Proteins) and abolishing their nuclear translocation.

  9. These data validate BRD4 (show BRD4 Proteins) as a major effector of respiratory syncytial virus-induced inflammation and disease. BRD4 (show BRD4 Proteins) is required for coupling NF-kappaB (show NFKB1 Proteins) to expression of inflammatory genes and the IRF (show TRIM63 Proteins)-RIG-I (show DDX58 Proteins) autoamplification pathway and independently facilitates antiviral interferon (show IFNA Proteins)-stimulated gene expression.

  10. IL-1beta/NF-kb signaling has a role in promoting colorectal cancer cell growth through miR-181a/PTEN axis

Pig (Porcine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. Zinc finger nuclease (show DCLRE1C Proteins) in-embryo editing of the RELA locus generated live born domestic pigs with the warthog RELA orthologue, associated with resilience to African Swine Fever.

  2. SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. Porcine Coro1A (show CORO1A Proteins) is an important immunity related gene that helps to inhibit NF-kB activation during H. parasuis infection.

  4. We propose that the variation in RELA identified between the warthog and domestic pig has the potential to underlie the difference between tolerance and rapid death upon African swine fever virus infection.

  5. The characterization of porcine NF-kappaB (show NFKB1 Proteins) p65 (show SYT1 Proteins) subunit (pp65 (show LCP1 Proteins)), is reported.

  6. Viral non-structural protein 1 suppressed host TNF-alpha (show TNF Proteins) promoter by inhibiting NF-kappaB (show NFKB1 Proteins) and Sp1 (show SP1 Proteins) promoter binding activity.

Cow (Bovine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. Hepatic SREBP-1c (show SREBF1 Proteins)-mediated lipid synthesis and the NF-kappaB (show NFKB1 Proteins) inflammatory pathway were both overinduced in cows with fatty liver.

  2. Cytopathic bovine viral diarrhea virus strain induces immune marker production in bovine cells through the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  3. The role of NF-kappaB (show NFKB1 Proteins) and C/EBP (show CEBPA Proteins) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.

  4. Altering the extracellular matrix to promote p38 (show MAPK14 Proteins) activation in cells on fibronectin (show FN1 Proteins) suppresses NF-kappaB (show NFKB1 Proteins) activation, suggesting a novel therapeutic strategy for treating

  5. full length coding sequence of the cattle transcription factor p65 was isolated and cloned

  6. the pathogen causing subclinical mastitis impairs NF-kappaB (show NFKB1 Proteins) activation in MEC (show CCL28 Proteins) thereby severely weakening the immune response,induction of IL-8 (show IL8 Proteins) and TNFalpha (show TNF Proteins), in the udder

  7. These results confirm that VEGI (show TNFSF15 Proteins) utilizes NF-kappaB (show NFKB1 Proteins) as a pro-survival role factor in endothelial cells.

Mouse (Murine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. this study shows that LPS (show TLR4 Proteins)-induced pro-inflammatory cytokine production is ameliorated in p65-deficient bone marrow-derived macrophages; however, p65-deficient 'activated' peritoneal macrophages exhibited elevated IL-1beta (show IL1B Proteins) and IL-6 (show IL6 Proteins)

  2. tis (show PDCD4 Proteins) study reveals the role of NF-kB signaling pathway in otitis media pathogenesis, and more specifically in mucosal proliferation

  3. Cardiac myocyte subpopulations differ in their NF-kappaB (show NFKB1 Proteins) subcellular localization and identify the cis (show CISH Proteins)-Golgi as a cardiac myocyte-specific host compartment.

  4. TCF-4 (show TCF4 Proteins) as a co-activator of p65 in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (show INS Proteins) resistance in mice.

  5. elevation of O-GlcNAcylation by overexpression of OGT (show OGT Proteins) increased the expression of p300 (show NOTCH1 Proteins), IKKalpha (show CHUK Proteins), and IKKbeta (show IKBKB Proteins) and promoted IKK (show CHUK Proteins)-mediated activating phosphorylation of p65 at Ser (show SIGLEC1 Proteins)-536, contributing to NF-kappaB (show NFKB1 Proteins) activation. In addition, we also identified phosphorylation of p65 at Thr (show TRH Proteins)-308, which might impair the O-GlcNAcylation of p65 at Thr (show TRH Proteins)-305.

  6. this study shows that that morin could exert the anti-inflammatory and anti-oxidative effects against LPS (show TLR4 Proteins)/D-GalN (show GAL Proteins)-induced acute liver injury by activating Nrf2 (show NFE2L2 Proteins) signal pathways and inhibiting NF-kappaB (show NFKB1 Proteins) activation

  7. We therefore concluded that in osteoblasts, P. gingivalis activated PKR (show EIF2AK2 Proteins), which in turn increased NLRP3 (show NLRP3 Proteins) expression by activating NF-kappaB (show NFKB1 Proteins). Our results suggest that PKR (show EIF2AK2 Proteins) modulates inflammation by regulating the expression of the NLRP3 (show NLRP3 Proteins) inflammasome through the NF-kappaB (show NFKB1 Proteins) pathway in periodontal diseases.

  8. this study shows that curcumin reduces the progression of progression of non-alcoholic steatohepatitis and liver damage, which may act via inhibiting HMGB1 (show HMGB1 Proteins)-NF-kappaB (show NFKB1 Proteins) translocation

  9. long term Cryptococcus neoformansinfection induces stable nuclear localization of p65 and IkappaBalpha (show NFKBIA Proteins) proteins in the absence of additional pro-inflammatory stimuli. In this case, nuclear localization of p65 is not accompanied by TNFalpha (show TNF Proteins) or inducible NOS (iNOS (show NOS2 Proteins)) expression.

  10. inhibition of mu-opioid receptor expression blocks morphine and DAMGO increases in the translocation of NF-kB p65 protein in microglia.a low dose of morphine, exerting its effects via the mu-opioid receptor, increases the DNA-binding activity of NF-kB via PKCepsilon, while a high dose of morphine triggers a nonopiate receptor response mediated by TLR4 and, interestingly, PKC signalling

p65 (NFkBP65) Protein Profile

Protein Summary

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with p65 (NFkBP65)

  • v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA)
  • v-rel avian reticuloendotheliosis viral oncogene homolog A (Rela)
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA)
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela)
  • NFkB protein
  • NFKB3 protein
  • p65 protein

Protein level used designations for NFkBP65

NF-kappa-B p65delta3 , nuclear factor NF-kappa-B p65 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 , transcription factor p65 , v-rel reticuloendotheliosis viral oncogene homolog A , nuclear factor kappa B subunit p65 , NF-kB p65 subunit , NF-kappaB transcription factor p65 subunit , v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 , avian reticuloendotheliosis viral (v-rel) oncogene homolog A , p65 NF kappaB , p65 NF-kappa B , p65 NFkB

GENE ID SPECIES
5970 Homo sapiens
309165 Rattus norvegicus
396027 Gallus gallus
100135665 Sus scrofa
508233 Bos taurus
19697 Mus musculus
100724366 Cavia porcellus
483729 Canis lupus familiaris
Selected quality suppliers for p65 Proteins (NFkBP65)
Did you look for something else?