Browse our p65 Proteins (NFkBP65)

Full name:
Nuclear Factor-KB P65 Proteins (NFkBP65)
On www.antibodies-online.com are 19 Nuclear Factor-KB P65 (NFkBP65) Proteins from 8 different suppliers available. Additionally we are shipping p65 Antibodies (1229) and p65 Kits (102) and many more products for this protein. A total of 1417 p65 products are currently listed.
Synonyms:
NFkB, NFKB3, p65
list all proteins Gene Name GeneID UniProt
NFkBP65 5970 Q04206
Rat NFkBP65 NFkBP65 309165  
NFkBP65 19697 Q04207

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p65 Proteins (NFkBP65) by Origin

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Top referenced p65 Proteins

  1. Human p65 Protein expressed in HEK-293 Cells - ABIN2730698 : Srinivasan, Blackburn, Lahiri: Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation. in Drug design, development and therapy 2015 (PubMed)
    Show all 5 references for 2730698

  2. Human p65 Protein expressed in Wheat germ - ABIN1317783 : Ba, Bacsi, Luo, Aguilera-Aguirre, Zeng, Radak, Brasier, Boldogh: 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Proteins for p65 Interaction Partners

Human Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. knockdown of RPA2 (show RPA2 Proteins) promoted formation of the menin (show MEN1 Proteins)-p65 (show GORASP1 Proteins) complex and repressed the expression of NF-kappaB (show NFKB1 Proteins)-mediated genes. RPA2 (show RPA2 Proteins) expression was induced via an E2F1 (show E2F1 Proteins)-dependent mechanism in MCF7 and MDA-MB-231 cells treated with NF-kappaB (show NFKB1 Proteins) activators, TNF-alpha (show TNF Proteins) or lipopolysaccharide (LPS (show IRF6 Proteins)).

  2. Consistent with these effects, RelA T505A mice exhibit earlier onset of cancer in the N-nitrosodiethylamine model of hepatocellular carcinoma. These data reveal a critical pathway controlling NF-kappaB (show NFKB1 Proteins) function in the liver that acts to suppress the tumour-promoting activities of RelA.

  3. NF-kappaB (show NFKB1 Proteins) RelB (show RELB Proteins) protein, but not RelA, displayed high expression in Endometrial cancer samples and cell lines.

  4. This study demonstrates for the first time that a prominent pathway of reovirus oncolysis of breast cancer is mediated through NF-kB p65 and that PUMA (show BBC3 Proteins) upregulation is dependent on NF-kB p65 activation.

  5. Site-differential phosphorylation of RelA/p65 modulates RITA (show ZNF331 Proteins) sensitivity in cancer cells.

  6. Vaccinia virus K1 inhibited acetylation of the RelA (p65) subunit of NF-kappaB (show NFKB1 Proteins), a nuclear event known to be required for NF-kappaB (show NFKB1 Proteins) activation.

  7. Within the nucleus, PKC-theta; catalytic activity maintains the Ser536 phosphorylation on the p65 subunit of NF-kappaB (also known as RelA) and can directly influence chromatin accessibility at transcriptional memory genes by regulating H2B deposition.

  8. A subset of leukemic tumors showed active BCR (show BCR Proteins) and NF-kappaB (show NFKB1 Proteins) signaling apparently independent of microenvironmental support. In one of these samples, we identified a novel somatic mutation in RELA (E39Q). This sample was resistant to ibrutinib-mediated inhibition of NF-kappaB (show NFKB1 Proteins) and apoptosis.

  9. to elucidate the induced activation of lytic pathway by ionizing radiation, irradiated SNU-719 cells were checked for the RelA and RelB (show RELB Proteins) expression by real-time PCR. RelB (show RELB Proteins) level showed a dose-dependent enhancement on 2nd and 4th day, whereas only a slight upregulation in RelA is noticed

  10. glatiramer acetate treatment also significantly reduced CD40 (show CD40 Proteins)-mediated P65 (show GORASP1 Proteins) phosphorylation in RRMS patients, suggesting that reducing CD40 (show CD40 Proteins)-mediated p-P65 (show GORASP1 Proteins) induction may be a general mechanism by which some current therapies modulate Multiple Sclerosis disease.

Pig (Porcine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (show PDCD4 Proteins)/NF-kappaB (show NFKB1 Proteins)/ TNF-alpha (show TNF Proteins) pathway in cardiomyocytes.

  2. Transmissible gastroenteritis virus infection activates NF-kappaB (show NFKB1 Proteins).

  3. Zinc finger nuclease (show DCLRE1C Proteins) in-embryo editing of the RELA locus generated live born domestic pigs with the warthog RELA orthologue, associated with resilience to African Swine Fever.

  4. SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  5. Porcine Coro1A (show CORO1A Proteins) is an important immunity related gene that helps to inhibit NF-kB activation during H. parasuis infection.

  6. We propose that the variation in RELA identified between the warthog and domestic pig has the potential to underlie the difference between tolerance and rapid death upon African swine fever virus infection.

  7. The characterization of porcine NF-kappaB (show NFKB1 Proteins) p65 (show SYT1 Proteins) subunit (pp65 (show LCP1 Proteins)), is reported.

  8. Viral non-structural protein 1 suppressed host TNF-alpha (show TNF Proteins) promoter by inhibiting NF-kappaB (show NFKB1 Proteins) and Sp1 (show SP1 Proteins) promoter binding activity.

Cow (Bovine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. Hepatic SREBP-1c (show SREBF1 Proteins)-mediated lipid synthesis and the NF-kappaB (show NFKB1 Proteins) inflammatory pathway were both overinduced in cows with fatty liver.

  2. Cytopathic bovine viral diarrhea virus strain induces immune marker production in bovine cells through the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  3. The role of NF-kappaB (show NFKB1 Proteins) and C/EBP (show CEBPA Proteins) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.

  4. Altering the extracellular matrix to promote p38 (show MAPK14 Proteins) activation in cells on fibronectin (show FN1 Proteins) suppresses NF-kappaB (show NFKB1 Proteins) activation, suggesting a novel therapeutic strategy for treating

  5. full length coding sequence of the cattle transcription factor p65 was isolated and cloned

  6. the pathogen causing subclinical mastitis impairs NF-kappaB (show NFKB1 Proteins) activation in MEC (show CCL28 Proteins) thereby severely weakening the immune response,induction of IL-8 (show IL8 Proteins) and TNFalpha (show TNF Proteins), in the udder

  7. These results confirm that VEGI (show TNFSF15 Proteins) utilizes NF-kappaB (show NFKB1 Proteins) as a pro-survival role factor in endothelial cells.

Mouse (Murine) Nuclear Factor-KB P65 (NFkBP65) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (show TRAF1 Proteins)/NF-kappaB (show NFKB1 Proteins)-regulated apoptosis and the p53 (show TP53 Proteins)/PCNA (show PCNA Proteins)- and ATM (show ATM Proteins)/ATR-Chk1 (show CHEK1 Proteins)/2-controlled DNA-damage response pathways.

  2. This study suggests that mTOR (show FRAP1 Proteins) activity in hepatocytes decreases hepatic vulnerability to injury through a mechanism dependent on NF-kappaB (show NFKB1 Proteins) proinflammatory cytokine signaling pathway in both normal and steatotic liver.

  3. this study demonstrates that lipopolysaccharides, TNF-alpha (show TNF Proteins), and viral infection, all of which induce robust inflammatory responses in naturally differentiated cells, failed to activate NF-kappaB (show NFKB1 Proteins), the key transcription factor that mediates inflammatory responses, and were unable to induce the expression of inflammatory genes in mouse embryonic stem cells. Similar results were obtained in human embryonic

  4. this study illustrates a significant role of RelA in mediating the corneal neovascularization

  5. Consistent with these effects, RelA T505A mice exhibit earlier onset of cancer in the N-nitrosodiethylamine model of hepatocellular carcinoma. These data reveal a critical pathway controlling NF-kappaB (show NFKB1 Proteins) function in the liver that acts to suppress the tumour-promoting activities of RelA.

  6. blockage of NF-kappaB (show NFKB1 Proteins) p65 and/or MAPK p38 (show MAPK1 Proteins) with their specific inhibitors strongly attenuated B7-H3 (show CD276 Proteins)-amplified inflammatory response with significantly reduced proinflammatory cytokine and chemokine (show CCL1 Proteins) production, and markedly ameliorated B7-H3 (show CD276 Proteins)-exacerbated disruption of blood-brain barrier and severity of disease status in S. pneumoniae-infected mice.

  7. our data show that Substance P (SP) treatment might be associated with anti-inflammatory effects in LPS (show TLR4 Proteins)-stimulated RAW 264.7 cells by suppressing NF-kappaB (show NFKB1 Proteins) (p65)activation and inducing HO-1 (show HMOX1 Proteins) expression.

  8. this study shows that LPS (show TLR4 Proteins)-induced pro-inflammatory cytokine production is ameliorated in p65-deficient bone marrow-derived macrophages; however, p65-deficient 'activated' peritoneal macrophages exhibited elevated IL-1beta (show IL1B Proteins) and IL-6 (show IL6 Proteins)

  9. tis (show PDCD4 Proteins) study reveals the role of NF-kB signaling pathway in otitis media pathogenesis, and more specifically in mucosal proliferation

  10. Cardiac myocyte subpopulations differ in their NF-kappaB (show NFKB1 Proteins) subcellular localization and identify the cis (show CISH Proteins)-Golgi as a cardiac myocyte-specific host compartment.

p65 (NFkBP65) Protein Profile

Protein Summary

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with p65 (NFkBP65)

  • v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA)
  • v-rel avian reticuloendotheliosis viral oncogene homolog A (Rela)
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA)
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela)
  • NFkB protein
  • NFKB3 protein
  • p65 protein

Protein level used designations for NFkBP65

NF-kappa-B p65delta3 , nuclear factor NF-kappa-B p65 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 , transcription factor p65 , v-rel reticuloendotheliosis viral oncogene homolog A , nuclear factor kappa B subunit p65 , NF-kB p65 subunit , NF-kappaB transcription factor p65 subunit , v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 , avian reticuloendotheliosis viral (v-rel) oncogene homolog A , p65 NF kappaB , p65 NF-kappa B , p65 NFkB

GENE ID SPECIES
5970 Homo sapiens
309165 Rattus norvegicus
396027 Gallus gallus
100135665 Sus scrofa
508233 Bos taurus
19697 Mus musculus
100724366 Cavia porcellus
483729 Canis lupus familiaris
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