Browse our RIPK1 (RIPK1) ELISA Kits

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Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 ELISA Kits (RIPK1)
On are 14 Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) ELISA Kits from 7 different suppliers available. Additionally we are shipping RIPK1 Antibodies (137) and RIPK1 Proteins (29) and many more products for this protein. A total of 191 RIPK1 products are currently listed.
2400006N03Rik, C9orf12, D330015H01Rik, RGD1311271, Rinp, Rip, Rip1, rIpk1, RP23-83I13.5
list all ELISA KIts Gene Name GeneID UniProt
RIPK1 306808 Q5PXE9
RIPK1 8737 Q13546
RIPK1 19766 Q60855

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RIPK1 (RIPK1) ELISA Kits by Reactivity

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More ELISA Kits for RIPK1 Interaction Partners

Human Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) interaction partners

  1. UL45 promoted the UL48-RIP1 interaction and re-localization of RIP1 to the UL48-containing virion assembly complex.

  2. we provide evidence that p62 (show GTF2H1 ELISA Kits) is implicated in the activation of NF-kappaB (show NFKB1 ELISA Kits) signaling that is partly dependent on RIP1

  3. inactivation of RIP1/RIP3 (show RIPK3 ELISA Kits) resulted in reduction of SOCS1 (show SOCS1 ELISA Kits) protein levels and partial differentiation of AML (show RUNX1 ELISA Kits) cells. AML (show RUNX1 ELISA Kits) cells with inactivated RIP1/RIP3 (show RIPK3 ELISA Kits) signaling show increased sensitivity to IFN-gamma-induced (show SAMHD1 ELISA Kits) differentiation.

  4. Data show that pan-caspase (show CASP3 ELISA Kits) inhibitors facilitated 5-fluorouracil (5-FU)-induced necroptosis mediated by secretion of tumor necrosis factor alpha (TNF-alpha (show TNF ELISA Kits)) driven by nuclear factor kappaB (NF-kappaB (show NFKB1 ELISA Kits)) and required RIP1 kinase.

  5. RIPK1 kinase activity is a pertinent therapeutic target to protect liver against excessive cell death in liver diseases.

  6. Ripk1 is directly involved in apoptosis/necroptosis. In osteosarcoma cells( OS) , small interfering RNA against Ripk1 prevented cell death induced by the sequestration of miR (show MLXIP ELISA Kits)-155-5p. Collectively, we show that miR (show MLXIP ELISA Kits)-148a-3p and miR (show MLXIP ELISA Kits)-155-5p are species-conserved deregulated miRNA in OS

  7. RIPK1 collaborates with TRAF2 (show TRAF2 ELISA Kits) to inhibit murine and human hepatocarcinogenesis.

  8. Necroptosis signaling is modulated by the kinase RIPK1 and requires the kinase RIPK3 and the pseudokinase MLKL. (Review)

  9. CYLD (show CYLD ELISA Kits) Promotes TNF-alpha (show TNF ELISA Kits)-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells

  10. TRAIL can enhance RIP1 and c-FLIPL (show CFLAR ELISA Kits) expression in HepG2 cells.

Mouse (Murine) Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) interaction partners

  1. Data show that the kinase domain of RIPK1 is a disease driver of intracerebral hemorrhage, mediating both acute cell death and functional outcome.

  2. MK2 (show KCNA2 ELISA Kits)-mediated phosphorylation of RIPK1 serves as a checkpoint within the TNF (show TNF ELISA Kits) signaling pathway that integrates cell survival and cytokine production.

  3. study identifies a novel role for RIPK1 and RIPK3 (show RIPK3 ELISA Kits), a pair of homologous serine/threonine kinases previously implicated in the regulation of necroptosis and pathologic tissue injury, in directing IFN-beta (show IFNB1 ELISA Kits) production in macrophagesges.

  4. this study shows that RIPK1 and RIPK3 (show RIPK3 ELISA Kits) account for acute inflammatory responses induced by lipopolysaccharide in vivo; notably, this regulation does not require exogenous manipulation of caspases

  5. these findings indicate that RIPK1 cooperates with NF-kappaB (show NFKB1 ELISA Kits) signaling to prevent TNFR1 (show TNFRSF1A ELISA Kits)-independent hepatocyte apoptosis and the development of chronic liver disease and cancer, but acts downstream of TNFR1 (show TNFRSF1A ELISA Kits) signaling to promote diethylnitrosamine-induced liver tumorigenesis.

  6. this study reveals a critical kinase-independent platform role for RIPK1 in protecting against TNF (show TNF ELISA Kits)/caspase (show CASP3 ELISA Kits)-dependent apoptosis of hepatocytes in immune-mediated liver injury

  7. Results revealed that RIPK1 and PGAM5 (show PGAM5 ELISA Kits) function independently to exert optimal control of Leishmania replication in the host.

  8. Knocking down receptor-interacting serine/threonine protein kinase 1 (Ripk1) increased both intracellular and extracellular PGRN (show GRN ELISA Kits) protein levels by increasing the translation rate of PGRN (show GRN ELISA Kits) without affecting mRNA levels.

  9. The findings reported here indicate that palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation of RAW 264.7 cells in the plasma membrane, which could provide a new mechanism to explain the link between elevated levels of free fatty acids (FFAs), palmitate in particular, and macrophage death.

  10. The results indicate that RIP1 and MLKL contribute to necroptotic cell death after HCoV-OC43 infection to limit viral replication.

RIPK1 Antigen Profile

Antigen Summary

Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.

Alternative names and synonyms associated with RIPK1

  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (LOC100230522) Elisa Kit
  • inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Ippk) Elisa Kit
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1) Elisa Kit
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1) Elisa Kit
  • RPA interacting protein (Rpain) Elisa Kit
  • 2400006N03Rik Elisa Kit
  • C9orf12 Elisa Kit
  • D330015H01Rik Elisa Kit
  • RGD1311271 Elisa Kit
  • Rinp Elisa Kit
  • Rip Elisa Kit
  • Rip1 Elisa Kit
  • rIpk1 Elisa Kit
  • RP23-83I13.5 Elisa Kit

Protein level used designations for RIPK1

receptor (TNFRSF)-interacting serine-threonine kinase 1 , 1,3,4,5,6-pentakisphosphate 2-kinase , inositol polyphosphate kinase 1 , inositol-1,3,4,5,6-pentakisphosphate 2-kinase , inositol-pentakisphosphate 2-kinase , ins(1,3,4,5,6)P5 2-kinase , insP5 2-kinase , RIP-1 , cell death protein RIP , receptor interacting protein , receptor-interacting protein 1 , receptor-interacting serine/threonine-protein kinase 1 , serine/threonine-protein kinase RIP , RPA interacting protein delta 2 , RPA interacting protein epsilon , RPA-interacting protein

100230522 Taeniopygia guttata
306808 Rattus norvegicus
8737 Homo sapiens
504727 Bos taurus
100524751 Sus scrofa
19766 Mus musculus
306886 Rattus norvegicus
69723 Mus musculus
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