Browse our anti-SLC39A3 (SLC39A3) Antibodies

Full name:
anti-Solute Carrier Family 39 (Zinc Transporter), Member 3 Antibodies (SLC39A3)
On www.antibodies-online.com are 29 Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) Antibodies from 13 different suppliers available. Additionally we are shipping SLC39A3 Proteins (3) and SLC39A3 Kits (1) and many more products for this protein. A total of 39 SLC39A3 products are currently listed.
Synonyms:
A170, AI845814, OSIL, p60, p62, p62B, PDB3, Zip3
list all antibodies Gene Name GeneID UniProt
SLC39A3 8878 Q13501
SLC39A3 106947 Q99K24
SLC39A3 314637 Q5U1X7

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Most Popular Reactivities for anti-SLC39A3 (SLC39A3) Antibodies

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anti-Human SLC39A3 Antibodies:

anti-Mouse (Murine) SLC39A3 Antibodies:

anti-Rat (Rattus) SLC39A3 Antibodies:

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Top referenced anti-SLC39A3 Antibodies

  1. Human Polyclonal SLC39A3 Primary Antibody for EIA, IHC (p) - ABIN955672 : Ollila, Soronen, Silander, Palo, Kieseppä, Kaunisto, Lönnqvist, Peltonen, Partonen, Paunio: Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. in Molecular psychiatry 2009 (PubMed)
    Show all 2 references for 955672

  2. Human Polyclonal SLC39A3 Primary Antibody for WB - ABIN949250 : Kanninen, Grubman, Caragounis, Duncan, Parker, Lidgerwood, Volitakis, Ganio, Crouch, White: Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis. in Biology open 2013 (PubMed)

More Antibodies against SLC39A3 Interaction Partners

Human Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) interaction partners

  1. SQSTM1-Nup214, although mostly cytoplasmic, also forms nuclear bodies and inhibits nuclear protein but not poly(A)(+) RNA export.

  2. autophagy upregulation by Sequestosome 1 (p62 (show SQSTM1 Antibodies)/SQSM1) knockdown ameliorated this cell injury and relieved insulin (show INS Antibodies) resistance

  3. This work suggests that UVA-induced p62 (show GTF2H1 Antibodies) acts through COX-2 (show COX2 Antibodies) to promote skin tumor growth and progression.

  4. we provide evidence that p62 (show GTF2H1 Antibodies) is implicated in the activation of NF-kappaB (show NFKB1 Antibodies) signaling that is partly dependent on RIP1 (show UQCRFS1 Antibodies)

  5. In this study, we first observed that p62-positive intranuclear aggregates also appeared in controls and were not specific for the Neuronal Intranuclear Hyaline Inclusion Disease cases.

  6. Data suggest that phosphorylation of SQSTM1 (show SQSTM1 Antibodies) by AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) and translocation of SQSTM1 (show SQSTM1 Antibodies) to mitochondria drives autophagic cell death in adult hippocampal neural stem cells; activation of AMPK (show PRKAA1 Antibodies) promotes autophagic cell death; inhibition of AMPK (show PRKAA1 Antibodies) (by enzyme inhibitor or RNA interference) suppresses autophagic cell death. (SQSTM1 (show SQSTM1 Antibodies) = sequestosome 1 (show SQSTM1 Antibodies))

  7. Authors found that p62/SQSTM1 (show SQSTM1 Antibodies), a protein upregulated in liver parenchymal cells but downregulated in HCC (show FAM126A Antibodies)-associated HSCs, negatively controls hepatic stellate cells activation.

  8. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

  9. p62/SQSTM1 (show SQSTM1 Antibodies), which accumulates in autophagy-defective cells, directly binds to and inhibits nuclear RNF168 (show RNF168 Antibodies), an E3 ligase essential for histone H2A ubiquitination and DNA damage responses. As a result, DNA repair proteins such as BRCA1, RAP80 (show UIMC1 Antibodies), and Rad51 (show RAD51 Antibodies) cannot be recruited to the sites of DNA double-strand breaks (DSBs), which impairs DSB repair.

  10. propose that the interplay between LRRK2 (show LRRK2 Antibodies) and p62 (show GTF2H1 Antibodies) may contribute to the pathophysiological function and homeostasis of LRRK2 (show LRRK2 Antibodies) protein

Mouse (Murine) Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) interaction partners

  1. ZnT3 (show Slc30a3 Antibodies) KO mice showed abnormality in trace fear conditioning is involved in associative fear memory and extinction, but not in innate fear.

  2. Znt-3-deficient mice lacking synaptic Zn also show less hippocampal cell damage following kainic acid injection. Zip transporters may provide selective therapeutic targets to protect these neurons from early Zn-induced neurodegeneration following injury.

  3. The expression of zinc transporter 3 (ZnT3 (show Slc30a3 Antibodies)) starts early in development, lasts throughout embryonic life, and is detected in proliferative and differentiating areas of the brain in distinct chelatable vesicular zinc pools.

  4. ZnT3 (show Slc30a3 Antibodies)-immunoreactive ependymal cells possess secretory activity directed towards the central canal.

  5. ZIP1 (show SLC39A1 Antibodies), ZIP2 (show Slc39a2 Antibodies) and ZIP3 may play cell-specific roles in zinc homeostasis rather than primary roles in the acquisition of dietary zinc

  6. ZIP1 (show SLC39A1 Antibodies) and ZIP3 zinc uptake transporter activity is controlled by zinc-stimulated endocytosis

  7. Reduced expression of Zip3 ultimately resulted in cell death, indicating that mammary epithelial cells have a unique requirement for Zip3-mediated Zn(2+) import.

  8. Knockout mice lacking Zip3 were generated and characterized.

  9. Mutations in the ZIP1 (show SLC39A1 Antibodies) and ZIP3 zinc transporter genes are silent when dietary intake of zinc is normal, but can dramatically compromise the success of pregnancy when dietary intake of zinc is limiting.

  10. temporal and spatial patterns of expression of the mouse ZIP1 (show SLC39A1 Antibodies), 3, 4, and 5 genes in the developing intestine and the effects of maternal dietary zinc deficiency on these patterns of expression were examined

SLC39A3 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SLC39A3

  • sequestosome 1 (SQSTM1) antibody
  • solute carrier family 39 (zinc transporter), member 3 (SLC39A3) antibody
  • solute carrier family 39 (zinc transporter), member 3 (Slc39a3) antibody
  • A170 antibody
  • AI845814 antibody
  • OSIL antibody
  • p60 antibody
  • p62 antibody
  • p62B antibody
  • PDB3 antibody
  • Zip3 antibody

Protein level used designations for SLC39A3

EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , sequestosome-1 , ubiquitin-binding protein p62 , ZIP-3 , solute carrier family 39 member 3 , zinc transporter ZIP3 , zrt- and Irt-like protein 3

GENE ID SPECIES
8878 Homo sapiens
29985 Homo sapiens
106947 Mus musculus
314637 Rattus norvegicus
505294 Bos taurus
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