Browse our TNFSF11 (TNFSF11) ELISA Kits

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Tumor Necrosis Factor (Ligand) Superfamily, Member 11 ELISA Kits (TNFSF11)
On are 118 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) ELISA Kits from 19 different suppliers available. Additionally we are shipping TNFSF11 Antibodies (324) and TNFSF11 Proteins (75) and many more products for this protein. A total of 534 TNFSF11 products are currently listed.
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
list all ELISA KIts Gene Name GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

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Top referenced TNFSF11 ELISA Kits

  1. Rat (Rattus) TNFSF11 ELISA Kit for Sandwich ELISA - ABIN416407 : Çankaya, Cizmeci ?enel, Kadioglu Duman, Muci, Dayisoylu, Balaban: The effects of chronic zoledronate usage on the jaw and long bones evaluated using RANKL and osteoprotegerin levels in an animal model. in International journal of oral and maxillofacial surgery 2013 (PubMed)
    Show all 8 references for 416407

  2. Human TNFSF11 ELISA Kit for Sandwich ELISA - ABIN415086 : Xue, Jiang, Cheng, Chen, Yu, Lin, Yang, Kong, Zhu, Xu, Wan, Zou: Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions. in PLoS ONE 2012 (PubMed)
    Show all 7 references for 415086

  3. Mouse (Murine) TNFSF11 ELISA Kit for Sandwich ELISA - ABIN424260 : Luo, Kang, Ma, Chen, Kuang, Huang, He, Peng: Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7. in Food science & nutrition 2014 (PubMed)
    Show all 3 references for 424260

More ELISA Kits for TNFSF11 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. Correlations between sRANKL and IL-18 (show IL18 ELISA Kits) in BALF.

  2. RANK/RANKL signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin (show TNFRSF11B ELISA Kits) to prevent bone metastasis.

  3. This study suggested that RANKL could be a marker to differentiate between pagetoid squamous cell carcinoma in situ and extramammary Paget disease .

  4. TNF-alpha-converting enzyme (show ADAM17 ELISA Kits) -mediated cleavage of soluble RANKL from activated lymphocytes, especially B cells, can promote osteoclastogenesis in periodontitis.

  5. RANKL is required for progesterone-mediated cell proliferation in BRCA1mut/+ breast tissue.

  6. MAOA (show MAOA ELISA Kits) provides tumor cell growth advantages in the bone microenvironment by stimulating interleukin-6 (IL6 (show IL6 ELISA Kits)) release from osteoblasts, and triggers skeletal colonization by activating osteoclastogenesis through osteoblast production of RANKL and IL6 (show IL6 ELISA Kits).

  7. In this review, we will provide a summary of the biological functions of RANK signaling pathway (receptor activator of nuclear factor kappaB ligand RANKL and its receptor RANK ) and downstream pathways in bone remodeling, immunity and epithelial homeostasis, with a particular emphasis on cancer

  8. The results showed that AG490 inhibited (p)-JAK2 (show JAK2 ELISA Kits) and RANKL expression.

  9. Review: OPG (show TNFRSF11B ELISA Kits), RANKL and TRAIL are involved in vascular calcification.

  10. Our results suggest that the polymorphism of the RANKL, RANK, and OPG (show TNFRSF11B ELISA Kits) genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. Data suggest that mutations at position I248 in DE-loop of murine RANKL have effects on interaction of RANKL with RANK and on subsequent activation of osteoclastogenesis by this hetero-multimer. (RANKL = osteoclast differentiation factor; RANK = tumor necrosis factor (show TNF ELISA Kits) receptor superfamily, member 11a protein)

  2. sRANKL increased macrophage glucose uptake at normal glucose concentrations, which was impaired by hyperglycemia pretreatment through the inhibition of Glut1 (show SLC2A1 ELISA Kits) membrane translocation and the insulin receptor (show INSR ELISA Kits) and IRS-1 (show IRS1 ELISA Kits) gene transcription.

  3. Our findings show that anti-RANKL antibody administration during pregnancy results in not only an undesirable increase in bone mass, but also has harmful effects on newborn survival.

  4. RANKL represses the transcription of the E3 ubiquitin ligase RNF146 (show RNF146 ELISA Kits) through an NF-kappaB (show NFKB1 ELISA Kits)-related inhibitory element in the RNF146 (show RNF146 ELISA Kits) promoter.

  5. This study showed that RANKL favors osteoclastogenesis via attenuation of Nrf2 (show NFE2L2 ELISA Kits)-mediated antioxidant enzyme expression by competing with Bach1 (show BACH1 ELISA Kits) nuclear accumulation.

  6. Membrane-bound RANKL induces M cell differentiation and CCL20 (show CCL20 ELISA Kits) expression in the follicle associated epithelium of gut (show GUSB ELISA Kits)-associated lymphoid tissues.

  7. The data show that S. aureus enhances bone resorption and periosteal osteoclast formation by increasing osteoblast RANKL production through TLR2 (show TLR2 ELISA Kits).

  8. Data (including data from studies using knockout mice) suggest that RANKL enhances TNF (show TNF ELISA Kits)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 (show TRAF6 ELISA Kits) by degrading Traf3 (show TRAF3 ELISA Kits), a known inhibitor of osteoclastogenesis. (RANKL = osteoclast differentiation factor; TNF (show TNF ELISA Kits) = tumor necrosis factor (show TNF ELISA Kits); Traf (show TRAF1 ELISA Kits) = TNF (show TNF ELISA Kits) receptor-associated factor)

  9. Results suggest that MAPK (show MAPK1 ELISA Kits) signaling pathway is necessary for receptor activator of nuclear factor kappa-B ligand (RANKL) expression in bone marrow stromal cell.

  10. endocortical resorption is driven by reduced osteoprotegerin (show TNFRSF11B ELISA Kits) rather than elevated RANKL expression

TNFSF11 Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) Elisa Kit
  • basic transcription factor 3 pseudogene 11 (BTF3P11) Elisa Kit
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) Elisa Kit
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) Elisa Kit
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) Elisa Kit
  • BTF3L1 Elisa Kit
  • CD254 Elisa Kit
  • hRANKL2 Elisa Kit
  • HUMBTFB Elisa Kit
  • Ly109l Elisa Kit
  • OCIF Elisa Kit
  • ODF Elisa Kit
  • Opg Elisa Kit
  • OPGL Elisa Kit
  • OPTB2 Elisa Kit
  • RANKL Elisa Kit
  • sOdf Elisa Kit
  • TNFRSF11B Elisa Kit
  • TNFSF11 Elisa Kit
  • Trance Elisa Kit

Protein level used designations for TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
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