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Browse our TNFSF11 (TNFSF11) ELISA Kits

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Tumor Necrosis Factor (Ligand) Superfamily, Member 11 ELISA Kits (TNFSF11)
On are 105 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) ELISA Kits from 16 different suppliers available. Additionally we are shipping TNFSF11 Antibodies (248) and TNFSF11 Proteins (53) and many more products for this protein. A total of 419 TNFSF11 products are currently listed.
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
list all ELISA KIts Gene Name GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

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Top referenced TNFSF11 ELISA Kits

  1. Rat (Rattus) TNFSF11 ELISA Kit for Sandwich ELISA - ABIN416342 : Gradosova, Zivna, Palicka, Hubena, Svejkovska, Zivny: Protective effect of amlodipine on rat bone tissue after orchidectomy. in Pharmacology 2012 (PubMed)
    Show all 9 references for ABIN416342

  2. Human TNFSF11 ELISA Kit for Sandwich ELISA - ABIN414912 : Xue, Jiang, Cheng, Chen, Yu, Lin, Yang, Kong, Zhu, Xu, Wan, Zou: Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions. in PLoS ONE 2012 (PubMed)
    Show all 6 references for ABIN414912

  3. Mouse (Murine) TNFSF11 ELISA Kit for Sandwich ELISA - ABIN415529 : Luo, Kang, Ma, Chen, Kuang, Huang, He, Peng: Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7. in Food science & nutrition 2014 (PubMed)

More ELISA Kits for TNFSF11 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. Switched memory B cells from RA patients expressed significantly more RANKL compared to healthy controls. B cells supported osteoclast differentiation in vitro in a RANKL-dependent manner.

  2. high level of mRANKL/RANK expression in cervical cancer lesions plays an important role in the rapid growth of cervical cancer cells possibly through strengthening the dialogue between cervical cancer cells and regulation of IL-8 (show IL8 ELISA Kits) secretion

  3. Transglutaminase 2 (show TGM2 ELISA Kits) up-regulation is associated with RANKL/OPG pathway

  4. The plasma OPG (show TNFRSF11B ELISA Kits) level is negatively associated with nonalcoholic fatty liver disease independent of potential cofounders

  5. Mast cell density and expression of MMP-9 (show MMP9 ELISA Kits), RANKL and Ntx correlated positively with of bone disease severity in multiple myeloma patients.

  6. Th17 cytokines have a dual effect on osteoclastogenesis in rheumatoid arthritis (RA): direct induction of osteoclastogenesis from monocytes and up-regulation of RANKL production in RA fibroblast-like synoviocytes (FLSs).

  7. these findings suggest a possible mechanism underlying the RANKL expression induced by wear particles in fibroblasts, and downregulating ER stress and the XBP1s expression of fibroblasts

  8. Taken together, these results suggested that the expression of RANKL induced by TiPs was mediated by ER stress in fibroblasts.

  9. Data show that receptor activator of nuclear factor kappa B ligand (RANKL) was elevated in anti-citrullinated protein antibodies (ACPA (show PRTN3 ELISA Kits))-positive and in anti-cit (show CIT ELISA Kits)-vimentin (show VIM ELISA Kits)-positive patients with early untreated rheumatoid arthritis (RA).

  10. qPCR and in silico hybridization revealed that miR (show MLXIP ELISA Kits)-124 and miR (show MLXIP ELISA Kits)-155 can be directly involved in the transcriptional regulation of Runt-related transcription factor 2 (RUNX2 (show RUNX2 ELISA Kits)) and receptor activator of nuclear factor kappa-B ligand (RANKL) genes.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) interaction partners

  1. OPG inhibits osteoclast differentiation via the MAPK (show MAPK1 ELISA Kits) signaling pathway.

  2. Stromal reticular cells activate lymphatic endothelial cells via RANKL and support the action of hematopoietic cell-derived lymphotoxin (show LTB ELISA Kits).

  3. SAA (show SAA1 ELISA Kits) inhibits osteoclast formation from mouse macrophages. SAA (show SAA1 ELISA Kits) blocks RANKL-induced osteoclastogenesis.

  4. Adseverin (show SCIN ELISA Kits) knockdown also suppressed the RANKL-mediated induction of nuclear factor of activated T-cell (show NFATC3 ELISA Kits) c1 (NFATc1 (show NFATC1 ELISA Kits)), which is a key transcription factor in osteoclastogenesis.

  5. Expression of RANKL is related to sex differences in collagen-induced arthritis

  6. Study reports that loss of the Opg gene results in deterioration of abdominal aortic aneurysms (AAA (show AAAS ELISA Kits)), possibly through involvement of TRAIL in smooth muscle actin (SMA (show SMN1 ELISA Kits))-positive cells and myofibroblasts.

  7. Data (including data from studies in transgenic mice) suggest RANKL induces incomplete cytokinesis (as well as cell fusion) as myeloid precursors commit to becoming polyploid osteoclasts; Akt (show AKT1 ELISA Kits) activation via phosphorylation appears to be involved.

  8. Results show that moderate increases in affinity for RANK lead to a substantial augmentation of osteoclast formation, signaling, and bone resorption suggesting a biphasic relationship between RANKL/RANK affinity and osteoclastogenic capacity.

  9. OPG induces osteoclasts and osteoclast progenitor cells apoptosis partly by the Fas (show FAS ELISA Kits)/FasL (show FASL ELISA Kits) signaling pathway.

  10. Although RL-D5 (enhancer) mediates RANKL expression in multiple lineages, other cell type- or factor-specific enhancers are required for its appropriate control, demonstrating the cell type-specific and complex regulation of RANKL expression.

TNFSF11 Antigen Profile

Antigen Summary

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) Elisa Kit
  • basic transcription factor 3 pseudogene 11 (BTF3P11) Elisa Kit
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) Elisa Kit
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) Elisa Kit
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) Elisa Kit
  • BTF3L1 Elisa Kit
  • CD254 Elisa Kit
  • hRANKL2 Elisa Kit
  • HUMBTFB Elisa Kit
  • Ly109l Elisa Kit
  • OCIF Elisa Kit
  • ODF Elisa Kit
  • Opg Elisa Kit
  • OPGL Elisa Kit
  • OPTB2 Elisa Kit
  • RANKL Elisa Kit
  • sOdf Elisa Kit
  • TNFRSF11B Elisa Kit
  • TNFSF11 Elisa Kit
  • Trance Elisa Kit

Protein level used designations for TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
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