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Browse our TNFSF13B Proteins (TNFSF13B)

Full name:
Tumor Necrosis Factor (Ligand) Superfamily, Member 13b Proteins (TNFSF13B)
On are 73 Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Proteins from 18 different suppliers available. Additionally we are shipping TNFSF13B Antibodies (286) and TNFSF13B Kits (47) and many more products for this protein. A total of 424 TNFSF13B products are currently listed.
BAFF, BLyS, CD257, D8Ertd387e, DTL, RGD1561519, TALL-1, TALL1, THANK, TNFSF13B, TNFSF20, zTNF4
list all proteins Gene Name GeneID UniProt
TNFSF13B 498666  
TNFSF13B 10673 Q9Y275
TNFSF13B 24099 Q9WU72

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TNFSF13B Proteins (TNFSF13B) by Origin

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Top referenced TNFSF13B Proteins

  1. Mouse (Murine) TNFSF13B Protein expressed in CHO Cells - ABIN2666770 : Koizumi, Hiasa, Kumagi, Yamanishi, Azemoto, Kobata, Matsuura, Abe, Onji: Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer. in PLoS ONE 2013 (PubMed)
    Show all 8 references for ABIN2666770

  2. Human TNFSF13B Protein expressed in CHO Cells - ABIN2666541 : Nardelli, Belvedere, Roschke, Moore, Olsen, Migone, Sosnovtseva, Carrell, Feng, Giri, Hilbert: Synthesis and release of B-lymphocyte stimulator from myeloid cells. in Blood 2001 (PubMed)
    Show all 8 references for ABIN2666541

  3. Human TNFSF13B Protein expressed in Escherichia coli (E. coli) - ABIN413043 : Kern, Cornuel, Billard, Tang, Rouillard, Stenou, Defrance, Ajchenbaum-Cymbalista, Simonin, Feldblum, Kolb: Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. in Blood 2004 (PubMed)

  4. Cynomolgus TNFSF13B Protein expressed in Human Cells - ABIN3216414 : Oren, Li, Volovik, Morris, Dharia, Das, Galperina, Gentz, Arnold: Structural basis of BLyS receptor recognition. in Nature structural biology 2002 (PubMed)

  5. Human TNFSF13B Protein expressed in Human - ABIN1344293 : Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: Selective APRIL blockade delays systemic lupus erythematosus in mouse. in PLoS ONE 2012 (PubMed)

More Proteins for TNFSF13B Interaction Partners

Horse (Equine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Equine adipose-derived stem cell (ASC (show PYCARD Proteins)) expresses BAFF (TNFSF13B) and its receptors, which may be associated with the differentiation process of ASC (show PYCARD Proteins) towards adipocyte.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. High levels of serum BAFF were associated with Multiple Myeloma.

  2. Expression of BAFF mRNA was not altered in patients with relapsing remitting multiple sclerosis.

  3. elevated BLyS levels in patients with systemic lupus erithematosus could be used to identify patients at risk of disease flare.

  4. Blood and salivary-gland BAFF-driven B-cell hyperactivity is associated to rituximab inefficacy in primary Sjogren's syndrome

  5. expression levels of B cell-activating factor (BAFF) and B-cell maturation antigen (show TNFRSF17 Proteins) were increased in multiple myeloma cells as compared with those in normal controls

  6. we consider recent observations of BAFF and its receptors in RA progression, as well as the effects of BAFF on the cell-cell interactions network. We also summarize the clinical development of BAFF antagonists for the treatment of RA

  7. BAFF gene expression play an important role with transplant tolerance in patients receiving kidney transplants.

  8. role of TLR3/BAFF axis in IgA class-switch recombination of IgA nephropathy

  9. results indicate that analysis of serum concentrations of BAFF and APRIL potentially represents a useful tool for the assessment of AIHA disease activity and progression.

  10. Abnormal levels of BAFF/APRIL in pediatric acute lymphoblastic leukemia suggest that BAFF/APRIL are associated with the development and progression of this disease in children

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. The Tnfas13b in the hippocampus in the prefrontal cortex of the DBA (show RPS19 Proteins)/2 J strain were up-regulated.

  2. early Ab responses contribute to the optimal formation of B cell memory through IgG-immune complexes and BAFF.

  3. autoimmunity induced by excessive BAFF production requires B1b B cells and CD19 (show CD19 Proteins) signaling.

  4. Data show that production of autoantibodies in B cell-activating factor of the TNF (show TNF Proteins) family (BAFF) is dependent on tumor necrosis factor (show TNF Proteins) receptor superfamily, member 13b protein (TACI (show TNFRSF13B Proteins)) expression by B cells.

  5. Cigarette smoke may hinder early mucosal IgA responses in the lung during influenza virus infection through oxidative inhibition of BAFF, which might contribute to the increased incidence and severity of viral infections in smokers.

  6. Data suggest that liver X receptor (LXR)/B (show NR1H2 Proteins)-lymphocyte stimulator (BLyS) pathway may serve as a target for the treatment of rheumatoid arthritis (RA).

  7. Antagonizing BAFF in cigarette smoke-exposed mice attenuates pulmonary inflammation and alveolar destruction.

  8. the elevated presence of APRIL and BLyS in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (show TNFSF11 Proteins)-expressing B cells/plasma cells.

  9. we have identified a novel role for BCMA (show TNFRSF17 Proteins) to control excess BAFF production in murine lupus through restraining the accumulation of BAFF-producing neutrophils.

  10. B cell activating factor (BAFF) and a proliferation inducing ligand (show TNFSF13 Proteins) (APRIL) mediate CD40 (show CD40 Proteins)-independent help by memory CD4 (show CD4 Proteins) T cells in transplantations.

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. study reports the molecular cloning, expression and bioactivity of the porcine homologue of human BAFF

  2. This study demonstrated expression of BAFF on cultured monocyte-derived dendritic cells, which was further enhanced by interferon-alpha (show IFNA Proteins) or interferon-gamma (show IFNG Proteins) treatment.

Rabbit Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Although BAFF expression is dispensable for B cell development in the bone marrow, it is required for B cell development in gut (show GUSB Proteins)-associated lymphoid tissue.

  2. BAFF and its receptors during B-cell activation (show BLNK Proteins) and autoantibody production in rabbits derived from selective breeding to develop a reproducible rabbit model of Systemic Lupus Erythematosus, were investigated.

  3. Cloning and expression analysis of B-cell activating factor (BAFF) provide the basis for investigation of its role in regulating rabbit B-lymphocyte (show AKAP17A Proteins) development and immune responses.

  4. BAFF was detected in developing appendix of young rabbits by immunohistochemical staining suggesting that BAFF plays a role during the period following birth when rabbit B-cell development is occurring.

TNFSF13B Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with TNFSF13B

  • tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b)
  • tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B)
  • BAFF protein
  • BLyS protein
  • CD257 protein
  • D8Ertd387e protein
  • DTL protein
  • RGD1561519 protein
  • TALL-1 protein
  • TALL1 protein
  • THANK protein
  • TNFSF13B protein
  • TNFSF20 protein
  • zTNF4 protein

Protein level used designations for TNFSF13B

tumor necrosis factor ligand superfamily member 13B , tumor necrosis factor (ligand) superfamily, member 13b , B-cell activating factor , B-lymphocyte stimulator , TNF- and APOL-related leukocyte expressed ligand 1 , ApoL related ligand TALL-1 , B-cell-activating factor , Delta4 BAFF , TNF and ApoL-related leukocyte expressed ligand 1 , TNF homolog that activates apoptosis , delta BAFF , dendritic cell-derived TNF-like molecule , tumor necrosis factor (ligand) superfamily, member 20 , tumor necrosis factor-like protein ZTNF4 , b cell-activating factor , tumor necrosis factor superfamily member 13b

498666 Rattus norvegicus
467323 Pan troglodytes
485545 Canis lupus familiaris
504507 Bos taurus
693917 Macaca mulatta
100051550 Equus caballus
10673 Homo sapiens
24099 Mus musculus
100038026 Sus scrofa
100101577 Oryctolagus cuniculus
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