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Browse our TNFSF13B Proteins (TNFSF13B)

Full name:
Tumor Necrosis Factor (Ligand) Superfamily, Member 13b Proteins (TNFSF13B)
On are 76 Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Proteins from 18 different suppliers available. Additionally we are shipping TNFSF13B Antibodies (299) and TNFSF13B Kits (54) and many more products for this protein. A total of 447 TNFSF13B products are currently listed.
BAFF, BLyS, CD257, D8Ertd387e, DTL, RGD1561519, TALL-1, TALL1, THANK, TNFSF13B, TNFSF20, zTNF4
list all proteins Gene Name GeneID UniProt
TNFSF13B 498666  
TNFSF13B 10673 Q9Y275
TNFSF13B 24099 Q9WU72

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TNFSF13B Proteins (TNFSF13B) by Origin

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Top referenced TNFSF13B Proteins

  1. Mouse (Murine) TNFSF13B Protein expressed in CHO Cells - ABIN2666770 : Koizumi, Hiasa, Kumagi, Yamanishi, Azemoto, Kobata, Matsuura, Abe, Onji: Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer. in PLoS ONE 2013 (PubMed)
    Show all 8 references for ABIN2666770

  2. Human TNFSF13B Protein expressed in CHO Cells - ABIN2666541 : Nardelli, Belvedere, Roschke, Moore, Olsen, Migone, Sosnovtseva, Carrell, Feng, Giri, Hilbert: Synthesis and release of B-lymphocyte stimulator from myeloid cells. in Blood 2001 (PubMed)
    Show all 8 references for ABIN2666541

  3. Human TNFSF13B Protein expressed in Escherichia coli (E. coli) - ABIN2001981 : Oren, Li, Volovik, Morris, Dharia, Das, Galperina, Gentz, Arnold: Structural basis of BLyS receptor recognition. in Nature structural biology 2002 (PubMed)

  4. Human TNFSF13B Protein expressed in Human - ABIN1344293 : Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: Selective APRIL blockade delays systemic lupus erythematosus in mouse. in PLoS ONE 2012 (PubMed)

More Proteins for TNFSF13B Interaction Partners

Horse (Equine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Equine adipose-derived stem cell (ASC (show PYCARD Proteins)) expresses BAFF (TNFSF13B) and its receptors, which may be associated with the differentiation process of ASC (show PYCARD Proteins) towards adipocyte.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Urinary APRIL (uAPRIL) and BAFF (uBAFF) levels were raised significantly in AN.

  2. During remission, serum CXCL13 (show CXCL13 Proteins) and BAFF levels have not decreased to normal in neuromyelitis optica patients, and B-cell-related autoimmune response persists. Immunosuppressive therapy decreased serum BAFF levels, but did not affect CXCL13 (show CXCL13 Proteins) expression.

  3. BAFF levels are lower in patients with antibody-mediated kidney rejection and also in patients with concurrent humoral and cellular rejection compared with patients without rejection

  4. The BLyS level is increased in some lupus patients. There was a moderate correlation with titers of anti-DNA antibody and disease activity.

  5. In Sjogren's syndrome (SS) patients, EULAR Sjogren's syndrome disease activity index (ESSDAI) is negatively associated with serum levels of 25(OH)-D3 and positively associated with BAFF.

  6. These results suggest that miR (show MLXIP Proteins)-202 functions as a modulator that can negatively regulate BAFF by inhibiting multiple myeloma tumor cell survival, growth, and adhesion in the bone marrow microenvironment.

  7. Variants in BAFF gene is associated with chronic lymphocytic leukemia.

  8. The results demonstrated that BAFF has an important role in the pathogenesis of newly diagnosed childhood immune thrombocytopenia.

  9. High levels of serum BAFF were associated with Multiple Myeloma.

  10. Expression of BAFF mRNA was not altered in patients with relapsing remitting multiple sclerosis.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Increased B-cell activating factor (BAFF) induced B cell differentiation into germinal center (GC) B (show NPR2 Proteins) cells within the autoimmune target tissue.

  2. The Tnfas13b in the hippocampus in the prefrontal cortex of the DBA (show RPS19 Proteins)/2 J strain were up-regulated.

  3. early Ab responses contribute to the optimal formation of B cell memory through IgG-immune complexes and BAFF.

  4. autoimmunity induced by excessive BAFF production requires B1b B cells and CD19 (show CD19 Proteins) signaling.

  5. Data show that production of autoantibodies in B cell-activating factor of the TNF (show TNF Proteins) family (BAFF) is dependent on tumor necrosis factor (show TNF Proteins) receptor superfamily, member 13b protein (TACI (show TNFRSF13B Proteins)) expression by B cells.

  6. Cigarette smoke may hinder early mucosal IgA responses in the lung during influenza virus infection through oxidative inhibition of BAFF, which might contribute to the increased incidence and severity of viral infections in smokers.

  7. Data suggest that liver X receptor (LXR)/B (show NR1H2 Proteins)-lymphocyte stimulator (BLyS) pathway may serve as a target for the treatment of rheumatoid arthritis (RA).

  8. Antagonizing BAFF in cigarette smoke-exposed mice attenuates pulmonary inflammation and alveolar destruction.

  9. the elevated presence of APRIL and BLyS in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (show TNFSF11 Proteins)-expressing B cells/plasma cells.

  10. we have identified a novel role for BCMA (show TNFRSF17 Proteins) to control excess BAFF production in murine lupus through restraining the accumulation of BAFF-producing neutrophils.

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. study reports the molecular cloning, expression and bioactivity of the porcine homologue of human BAFF

  2. This study demonstrated expression of BAFF on cultured monocyte-derived dendritic cells, which was further enhanced by interferon-alpha (show IFNA Proteins) or interferon-gamma (show IFNG Proteins) treatment.

Rabbit Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) interaction partners

  1. Although BAFF expression is dispensable for B cell development in the bone marrow, it is required for B cell development in gut (show GUSB Proteins)-associated lymphoid tissue.

  2. BAFF and its receptors during B-cell activation (show BLNK Proteins) and autoantibody production in rabbits derived from selective breeding to develop a reproducible rabbit model of Systemic Lupus Erythematosus, were investigated.

  3. Cloning and expression analysis of B-cell activating factor (BAFF) provide the basis for investigation of its role in regulating rabbit B-lymphocyte (show AKAP17A Proteins) development and immune responses.

  4. BAFF was detected in developing appendix of young rabbits by immunohistochemical staining suggesting that BAFF plays a role during the period following birth when rabbit B-cell development is occurring.

TNFSF13B Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with TNFSF13B

  • tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b)
  • tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B)
  • BAFF protein
  • BLyS protein
  • CD257 protein
  • D8Ertd387e protein
  • DTL protein
  • RGD1561519 protein
  • TALL-1 protein
  • TALL1 protein
  • THANK protein
  • TNFSF13B protein
  • TNFSF20 protein
  • zTNF4 protein

Protein level used designations for TNFSF13B

tumor necrosis factor ligand superfamily member 13B , tumor necrosis factor (ligand) superfamily, member 13b , B-cell activating factor , B-lymphocyte stimulator , TNF- and APOL-related leukocyte expressed ligand 1 , ApoL related ligand TALL-1 , B-cell-activating factor , Delta4 BAFF , TNF and ApoL-related leukocyte expressed ligand 1 , TNF homolog that activates apoptosis , delta BAFF , dendritic cell-derived TNF-like molecule , tumor necrosis factor (ligand) superfamily, member 20 , tumor necrosis factor-like protein ZTNF4 , b cell-activating factor , tumor necrosis factor superfamily member 13b

498666 Rattus norvegicus
467323 Pan troglodytes
485545 Canis lupus familiaris
504507 Bos taurus
693917 Macaca mulatta
100051550 Equus caballus
10673 Homo sapiens
24099 Mus musculus
100038026 Sus scrofa
100101577 Oryctolagus cuniculus
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