Browse our anti-TRADD (TRADD) Antibodies

Full name:
anti-TNFRSF1A-Associated Via Death Domain Antibodies (TRADD)
On are 121 TNFRSF1A-Associated Via Death Domain (TRADD) Antibodies from 27 different suppliers available. Additionally we are shipping TRADD Proteins (14) and TRADD Kits (3) and many more products for this protein. A total of 146 TRADD products are currently listed.
9130005N23Rik, AA930854, Hs.89862, tradd, wu:fc59e02, zgc:103556
list all antibodies Gene Name GeneID UniProt
TRADD 8717 Q15628
TRADD 71609 Q3U0V2
TRADD 246756  

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anti-Human TRADD Antibodies:

anti-Mouse (Murine) TRADD Antibodies:

anti-Rat (Rattus) TRADD Antibodies:

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Top referenced anti-TRADD Antibodies

  1. Human Monoclonal TRADD Primary Antibody for IF, IP - ABIN968045 : He, Ting: A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. in Molecular and cellular biology 2002 (PubMed)
    Show all 5 references for 968045

  2. Human Monoclonal TRADD Primary Antibody for WB - ABIN967541 : Hsu, Shu, Pan, Goeddel: TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. in Cell 1996 (PubMed)
    Show all 3 references for 967541

  3. Human Polyclonal TRADD Primary Antibody for EIA, FACS - ABIN955307 : Pointon, Harvey, Karaderi, Appleton, Farrar, Stone, Sturrock, Reveille, Weisman, Ward, Brown, Wordsworth: The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD). in Annals of the rheumatic diseases 2010 (PubMed)
    Show all 2 references for 955307

  4. Human Polyclonal TRADD Primary Antibody for IHC (p), IHC - ABIN407974 : Chakraborty, Li, Tang, Xie, Puliyappadamba, Raisanen, Burma, Boothman, Cochran, Wu, Habib: Cytoplasmic TRADD confers a worse prognosis in glioblastoma. in Neoplasia (New York, N.Y.) 2013 (PubMed)

  5. Human Polyclonal TRADD Primary Antibody for IP, IHC - ABIN223257 : Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells. in The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal TRADD Primary Antibody for IF (p), IHC (p) - ABIN673314 : Chen, Zhang, Zhang, Li, Sun: Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling. in Biochemical and biophysical research communications 2016 (PubMed)

  7. Dog (Canine) Polyclonal TRADD Primary Antibody for WB - ABIN2792121 : Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. in Rheumatology (Oxford, England) 2008 (PubMed)

More Antibodies against TRADD Interaction Partners

Human TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. These data for the first time identifies miR (show MLXIP Antibodies)-485-5p/TRADD axis in hydrogen sulfide (show SQRDL Antibodies) protecting against TNF-alpha (show TNF Antibodies)-induced neuronal cell apoptosis.

  2. By reducing the levels of TRADD, wild type CFTR suppresses downstream proinflammatory NFkappaB signaling.

  3. NPM (show NPM1 Antibodies)-RAR (show RARA Antibodies) binding to TRADD selectively inhibits caspase (show CASP3 Antibodies) activation, while allowing activation of NFkappaB (show NFKB1 Antibodies) and JNK (show MAPK8 Antibodies)

  4. The release of extracellular vesicles was triggered by TNFA (show TNF Antibodies) from BEAS-2b cells.TNFA-triggered extracellular vesicles contained TNFR1 (show TNFRSF1A Antibodies) and TRADD.

  5. MicroRNA-30c-2-3p negatively regulates NF-kappaB (show NFKB1 Antibodies) signaling and cell cycle progression through downregulation of TRADD and CCNE1 (show CCNE1 Antibodies) in breast cancer.

  6. domains of calmodulin (show CALM1 Antibodies) mediate FADD (show FADD Antibodies) and TRADD interaction

  7. PA induced the apoptosis of HUVECs by initiating the death pathway (TNF-R1 (show TNFRSF1A Antibodies)/TRADD/caspases 8 pathway), whereas AA enhanced cell survival to protect vascular endothelial cells by activating the survival pathway (TNF-R1 (show TNFRSF1A Antibodies)/RIP (show HRB Antibodies)/NF-kappaB (show NFKB1 Antibodies) 50/NF-kappaB (show NFKB1 Antibodies) 65).

  8. Biologic assessment found that NPM (show NPM1 Antibodies)-RAR (show RARA Antibodies) expression impaired TNF (show TNF Antibodies)-induced signaling through TRADD, blunting TNF (show TNF Antibodies)-mediated activation of caspase-3 (CASP3 (show CASP3 Antibodies)) and caspase-8 (CASP8 (show CASP8 Antibodies)), to ultimately block apoptosis.

  9. TRADD gene expression was knocked down by an antisense oligonucleotide.

  10. structure-based mutations of TNFR-1 (show TNFRSF1A Antibodies) (P367A and P368A), TRADD (F266A), and RIP1 (show UQCRFS1 Antibodies) (M637A and R638A) disrupted formation of the death domain (DD) complex and prevented stable interactions among those DDs

Mouse (Murine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. TRADD knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (show NR2C2 Antibodies)/p38 MAPK (show MAPK14 Antibodies) but not AKT (show AKT1 Antibodies) phosphorylation

  2. Data indicate that ASK1 (show MAP3K5 Antibodies) activation stimulated the activity of the transcription factor FoxO3a (show FOXO3 Antibodies), which increased the abundance of the apoptosis-promoting adaptor protein TRADD, leading to activation of caspase 8 (show CASP8 Antibodies).

  3. data indicate that TRADD shuttles dynamically from the cytoplasm into the nucleus to modulate the interaction between p19(Arf (show CDKN2A Antibodies)) and its E3 ubiquitin ligase (show MUL1 Antibodies) ULF (show TRIP12 Antibodies), thereby promoting p19(Arf (show CDKN2A Antibodies)) protein stability and tumour suppression

  4. Data suggest that deficiency of TRADD sensitizes cells to TRAIL-induced apoptosis, and that enhanced cell death in TRADD(-/-) MEFs is associated with defective NF-kappaB (show NFKB1 Antibodies) activation.

  5. TRADD is required for recruitment of receptor interacting protein 1 (show RIPK1 Antibodies) and TNFR (show TNFRSF1A Antibodies)-associated factor 2 to the DR3 (show TNFRSF25 Antibodies) signaling complex and for the ubiquitination of receptor interacting protein 1 (show RIPK1 Antibodies)

  6. We show that TRADD is recruited to the TRAIL-receptor complex, and RIP1 (show RALBP1 Antibodies) recruitment is mediated by TRADD.

  7. TRADD may be involved in IFN-gamma (show IFNG Antibodies) signaling by forming a complex with STAT1 (show STAT1 Antibodies)-alpha within the nucleus and regulating IFN-gamma (show IFNG Antibodies)-mediated STAT1 (show STAT1 Antibodies)-alpha activation.

  8. Tradd activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm.

  9. silencing TRADD expression with small-interfering RNA reduced neuronal apoptosis and subsequent microglial and astroglial activation

  10. TRADD is a multifunctional protein crucial both for TNFR1 (show TNFRSF1A Antibodies) signaling and other signaling pathways relevant to immune responses.

Cow (Bovine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. TNF (show TNF Antibodies) binding induces release of AIP1 (DAB2IP (show DAB2IP Antibodies)) from TNFR1 (show TNFRSF1A Antibodies), resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD, RIP1 (show RALBP1 Antibodies), TRAF2 (show TRAF2 Antibodies), and AIPl.

TRADD Antigen Profile

Antigen Summary

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

Alternative names and synonyms associated with TRADD

  • TNFRSF1A-associated via death domain (TRADD) antibody
  • TNFRSF1A-associated via death domain (LOC100337888) antibody
  • conjugal transfer protein D (traDd) antibody
  • TNFRSF1A-associated via death domain (Tradd) antibody
  • TNFRSF1A-associated via death domain (tradd) antibody
  • tnfrsf1a-associated via death domain (tradd) antibody
  • tnfrsf1a-associated via death domain protein (LOC100136668) antibody
  • 9130005N23Rik antibody
  • AA930854 antibody
  • Hs.89862 antibody
  • tradd antibody
  • wu:fc59e02 antibody
  • zgc:103556 antibody

Protein level used designations for TRADD

TNFRSF1A-associated via death domain , conjugal transfer protein D , TNFR1-associated death domain protein , tumor necrosis factor receptor type 1 associated death domain protein , tumor necrosis factor receptor type 1-associated DEATH domain protein , tumor necrosis factor receptor-1-associated protein , TNF receptor 1 associated signal transducer , TNFR1-associated DEATH domain protein , Tumor necrosis factor receptor type 1-associated DEATH domain protein , TNFRSF1A-associated via death domain protein

415700 Gallus gallus
454154 Pan troglodytes
100337888 Oryctolagus cuniculus
7369642 Agrobacterium radiobacter K84
8717 Homo sapiens
71609 Mus musculus
246756 Rattus norvegicus
611262 Canis lupus familiaris
504707 Bos taurus
733418 Xenopus laevis
58130 Danio rerio
100136668 Oncorhynchus mykiss
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