Browse our ADAM17 (ADAM17) ELISA Kits

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ADAM Metallopeptidase Domain 17 ELISA Kits (ADAM17)
On www.antibodies-online.com are 34 ADAM Metallopeptidase Domain 17 (ADAM17) ELISA Kits from 14 different suppliers available. Additionally we are shipping ADAM17 Antibodies (272) and ADAM17 Proteins (17) and many more products for this protein. A total of 332 ADAM17 products are currently listed.
Synonyms:
adam17, ADAM18, CD156B, CSVP, NISBD, si:dkey-81b15.2, Tace
list all ELISA KIts Gene Name GeneID UniProt
ADAM17 11491 Q9Z0F8
ADAM17 6868 P78536
ADAM17 57027 Q9Z1K9

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Top referenced ADAM17 ELISA Kits

  1. ABIN1882558 : Cardellini, Menghini, Martelli, Casagrande, Marino, Rizza, Porzio, Mauriello, Solini, Ippoliti, Lauro, Folli, Federici: TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. in Diabetes 2009 (PubMed)
    Show all 33 references for 1882558

  2. Mouse (Murine) ADAM17 ELISA Kit for Sandwich ELISA - ABIN810367 : Lagrange, Li, Fassot, Bourhim, Louis, Nguyen Dinh Cat, Parlakian, Wahl, Lacolley, Jaisser, Regnault: Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 (PubMed)

  3. Human ADAM17 ELISA Kit for Sandwich ELISA - ABIN415265 : Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. in International wound journal 2016 (PubMed)

More ELISA Kits for ADAM17 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Conditional ADAM17 knockout mice lacking ADAM17 in all leukocytes had a significant survival advantage during severe polymicrobial sepsis induced by CLP, associated with enhanced neutrophil recruitment at the infectious locus along with decreased bacterial spread and circulating levels of proinflammatory factors. Its induction during sepsis may tip the balance between efficient and impaired neutrophil recruitment.

  2. These results demonstrate a novel physiologic role for a disintegrin and metalloprotease 17 in regulating murine IL-6 (show IL6 ELISA Kits) signals during inflammatory processes.

  3. These results show that TACE is a target of, and is downregulated by, soluble TNF (show TNF ELISA Kits)-induced AP-2alpha (show TFAP2A ELISA Kits) transcription factor in dendritic cells

  4. the critical role of the transmembrane domains of ADAM17 and Rhbdf2 (show RHBDF2 ELISA Kits) in the regulation of the ADAM17 and EGFR (show EGFR ELISA Kits), and ADAM17 and TNFalpha (show TNF ELISA Kits) signaling pathways, was examined.

  5. Findings provide evidence that ADAM10 (show ADAM10 ELISA Kits), and not ADAM17, is indispensable for proper retinal development as a regulator of NOTCH (show NOTCH1 ELISA Kits) signaling.

  6. this study shows that the iRhom2 (show RHBDF2 ELISA Kits)/ADAM17 pathway plays an important role in regulating CSF1R (show CSF1R ELISA Kits) expression in the myeloid cell compartment at steady state, and in modulating development of monocytes/macrophages during their repopulation

  7. Suggest an atheroprotective role of ADAM17, which might be mediated by cleaving membrane-bound TNFalpha (show TNF ELISA Kits) and TNFR2 (show TNFRSF1B ELISA Kits), thereby preventing overactivation of endogenous TNFR2 (show TNFRSF1B ELISA Kits) signaling in cells of the vasculature.

  8. Aging and obesity cooperatively reduce caveolin-1 (show CAV1 ELISA Kits) expression and increase vascular endothelial ADAM17 activity and soluble TNF (show TNF ELISA Kits) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  9. Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10 (show ADAM10 ELISA Kits)/17 and intramembrane protease gamma-secretase.

  10. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (show AXL ELISA Kits)kinase (Axl) in lupus-prone leukocytes.

Human ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. TNF-alpha-converting enzyme -mediated cleavage of soluble RANKL (show TNFSF11 ELISA Kits) from activated lymphocytes, especially B cells, can promote osteoclastogenesis in periodontitis.

  2. Cell stimulation can downregulate expression of mature ADAM17 from the cell surface and induce release of exosomal ADAM17, which can then distribute and contribute to substrate shedding on more distant cells.

  3. Aging and obesity cooperatively reduce caveolin-1 (show CAV1 ELISA Kits) expression and increase vascular endothelial ADAM17 activity and soluble TNF (show TNF ELISA Kits) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  4. Our data demonstrated that elevated serum Semaphorin5A (Sema5A (show SEMA5A ELISA Kits)) in SLE patients correlated with disease activity and are involved in kidney and blood system damage; ADAM17 might be involved in the release of secreted Sema5A (show SEMA5A ELISA Kits).

  5. ADAM17 and ADAM10 (show ADAM10 ELISA Kits) cleave Nectin-4 (show PVRL4 ELISA Kits) and release soluble Nectin-4 (show PVRL4 ELISA Kits) (sN4).

  6. ADAM17 promotes epithelial-mesenchymal transition via the TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits) pathway. the present study demonstrates that ADAM17 plays a critical role in the development of gastric cancer and provides a potential therapeutic target for gastric cancer.

  7. FHL2 (show FHL2 ELISA Kits) interacts with ADAM-17 in normal, dysplastic and malignant colon epithelial cells. Colocalisation of these proteins is more frequent in malignant than in normal and dysplastic cells, suggesting a role for ADAM-17/FHL2 (show FHL2 ELISA Kits) complex in the development of colorectal cancer.

  8. The present study suggests that ADAM17-siRNA inhibits MCF-7 breast cancer and is activated through the EGFR (show EGFR ELISA Kits)-PI3K (show PIK3CA ELISA Kits)-AKT (show AKT1 ELISA Kits) signaling pathway

  9. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (show AXL ELISA Kits)) is rescued by combined matrix metalloproteases ADAM10 (show ADAM10 ELISA Kits) and TACE (ADAM17) inhibition.

  10. the TLR4 (show TLR4 ELISA Kits)/Gal-1 (show LGALS1 ELISA Kits) signaling pathway regulates lactate-mediated EMT (show ITK ELISA Kits) processes through the activation of ADAM10 (show ADAM10 ELISA Kits) and ADAM17 in colon cancer cells.

Pig (Porcine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. ADAM17 was involved in porcine CD16 (show CD16 ELISA Kits) shedding in porcine reproductive and respiratory syndrome virus-infected pigs.

  2. Overexpression of ADAM17 induced downregulation of CD163 (show CD163 ELISA Kits) expression and a reduction in reproductive and respiratory syndrome virus infection.

  3. activation of TACE/ADAM17 via a PKC (show FYN ELISA Kits)-induced c-Src (show SRC ELISA Kits)-dependent manner mediates proteolytic activation of the EGF (show EGF ELISA Kits)-like factors that are involved in the induction of granulosa cell differentiation, cumulus expansion, and meiotic maturation of porcine oocytes

  4. Data indicate that TNF-alpha (show TNF ELISA Kits) stimulates Rac (show AKT1 ELISA Kits), ADAM17/TACE, and RhoA (show RHOA ELISA Kits) through the guanine nucleotide exchange factor (show ARHGEF12 ELISA Kits) (GEF)-H1 (show ARHGEF2 ELISA Kits).

  5. progesterone-induced TACE/ADAM17 leads to production of soluble EGF (show EGF ELISA Kits) domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes

ADAM17 Antigen Profile

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway.

Alternative names and synonyms associated with ADAM17

  • ADAM metallopeptidase domain 17 (ADAM17) Elisa Kit
  • a disintegrin and metallopeptidase domain 17b (adam17b) Elisa Kit
  • ADAM metallopeptidase domain 17 (adam17) Elisa Kit
  • a disintegrin and metallopeptidase domain 17 (Adam17) Elisa Kit
  • ADAM metallopeptidase domain 17 (Adam17) Elisa Kit
  • adam17 Elisa Kit
  • ADAM18 Elisa Kit
  • CD156B Elisa Kit
  • CSVP Elisa Kit
  • NISBD Elisa Kit
  • si:dkey-81b15.2 Elisa Kit
  • Tace Elisa Kit

Protein level used designations for ADAM17

ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) , a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) , disintegrin and metalloproteinase domain-containing protein 17 , tumor necrosis factor alpha converting enzyme , a disintegrin and metallopeptidase domain 17 , ADAM metallopeptidase domain 17 , a disintegrin and metalloprotease domain 17 , disintegrin metalloproteinase , disintegrin and metalloproteinase domain-containing protein 17-like , ADAM 17 , TNF-alpha convertase , TNF-alpha converting enzyme , TNF-alpha-converting enzyme , a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme , a disintegrin and metalloproteinase domain 17 , ADAM metallopeptidase domain 18 , snake venom-like protease , tumor necrosis factor, alpha, converting enzyme

GENE ID SPECIES
421931 Gallus gallus
459018 Pan troglodytes
560657 Danio rerio
694429 Macaca mulatta
733430 Xenopus laevis
100072496 Equus caballus
100406520 Callithrix jacchus
100482770 Ailuropoda melanoleuca
11491 Mus musculus
6868 Homo sapiens
57027 Rattus norvegicus
475662 Canis lupus familiaris
397343 Sus scrofa
517541 Bos taurus
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