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FBXW7 Proteins

(F-Box and WD Repeat Domain Containing 7 (FBXW7))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
FBXW7 Protein (AA 599-707) (GST tag) FBXW7 Protein (AA 599-707) (GST tag) FBXW7 Protein (AA 599-707) (GST tag) (ABIN1353879)

FBXW7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

FBXW7 Protein (AA 1-553) (GST tag) FBXW7 Protein (AA 1-553) (GST tag) FBXW7 Protein (AA 1-553) (GST tag) (ABIN1990130)

FBXW7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

FBXW7 Protein (AA 1-707) (His tag) FBXW7 Protein (AA 1-707) (His tag) FBXW7 Protein (AA 1-707) (His tag) (ABIN3092548)

Crystallography grade FBXW7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

FBXW7 Proteins by Grade

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FBXW7 Proteins by Origin

Find FBXW7 Proteins for a variety of species such as anti-Human FBXW7, anti-Mouse FBXW7. The species listed below are among those available. Click on a link to go to the corresponding products.

FBXW7 Proteins by Source

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FBXW7 Proteins by Protein Type

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FBXW7 Proteins by Application

Find FBXW7 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FBXW7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353879
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1990130
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092548
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136692
Quantity 1 mg
Datasheet Datasheet

Aliases for FBXW7 Proteins

F-box and WD repeat domain containing 7 (Fbxw7) Proteins
F-box and WD repeat domain containing 7 (FBXW7) Proteins
F-box and WD repeat domain containing 7 (fbxw7) Proteins
F-box and WD-40 domain protein 7 (Fbxw7) Proteins
1110001A17Rik Proteins
AGO Proteins
cdc4 Proteins
CDC4 Proteins
Cdc4 Proteins
FBW6 Proteins
FBW7 Proteins
Fbw7 Proteins
Fbwd6 Proteins
FBX30 Proteins
Fbx30 Proteins
FBXO30 Proteins
Fbxo30 Proteins
FBXW6 Proteins
Fbxw6 Proteins
hAgo Proteins
hCdc4 Proteins
SEL-10 Proteins
SEL10 Proteins
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