Browse our NOTCH3 (NOTCH3) ELISA Kits

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Notch 3 ELISA Kits (NOTCH3)
On www.antibodies-online.com are 8 Notch 3 (NOTCH3) ELISA Kits from 6 different suppliers available. Additionally we are shipping NOTCH3 Antibodies (207) and NOTCH3 Proteins (10) and many more products for this protein. A total of 229 NOTCH3 products are currently listed.
Synonyms:
AW229011, CADASIL, CASIL, fa14b08, hpbk, IMF2, N3, notch5, wu:fa14b08
list all ELISA KIts Gene Name GeneID UniProt
NOTCH3 4854 Q9UM47
NOTCH3 18131 Q61982
NOTCH3 56761 Q9R172

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NOTCH3 (NOTCH3) ELISA Kits by Reactivity

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More ELISA Kits for NOTCH3 Interaction Partners

Human Notch 3 (NOTCH3) interaction partners

  1. Data indicate that mRNA high expression level of Notch1 (show NOTCH1 ELISA Kits) was associated with better overall survival (OS) for all NSCLC, hazard ratio (HR), better OS in adenocarcinoma (Ade), HR, as well as in squamous cell carcinoma (SCC (show CYP11A1 ELISA Kits)), HR, and mRNA high expression levels of Notch2 (show NOTCH2 ELISA Kits) and Notch3 were associated with worsen OS for all NSCLC, and mRNA high expression level of Notch4 (show NOTCH4 ELISA Kits) was not found to be associated with to OS for all NSCLC.

  2. MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3 pathway.

  3. Intermittent compressive stress regulates Notch (show NOTCH1 ELISA Kits) receptor and target gene expression via the TGF-beta (show TGFB1 ELISA Kits) signaling pathway. Notch (show NOTCH1 ELISA Kits) signaling participates in TGF-beta (show TGFB1 ELISA Kits)-induced sclerostin (show SOST ELISA Kits) expression in periodontal ligament cells.

  4. Specific Notch3 and Jag1 (show JAG1 ELISA Kits) subcellular localization patterns may provide clues for the behavior of the corresponding tumors and could potentially be applied in the clinic for Jag1 (show JAG1 ELISA Kits) targeting in triple-negative breast cancer patients

  5. there is a cross-talk between Jagged1 (show JAG1 ELISA Kits)/Notch3 and VEGF (show VEGFA ELISA Kits) in TNBC angiogenesis. Jagged1 (show JAG1 ELISA Kits)/Notch3 is expected to be an important signaling pathway for TNBC progression and a potential target for TNBC neovascularization therapy.

  6. Mutations in NOTCH3 gene is associated with T-cell acute lymphoblastic leukemia.

  7. Loss of Notch3 expression may be fundamental to the process of dedifferentiation that accompanies thyroid oncogenesis. Conversely, activation of Notch3 in thyroid cancer exerts an antiproliferative effect and restores elements of a differentiated phenotype

  8. Notch3 and pS6 are significantly related to ovarian epithelial cancer development and prognosis, and their combination represents a potential biomarker and therapeutic target in ovarian tumor angiogenesis.

  9. NOTCH3 381C>T and 1735T>C polymorphisms were associated with Ischemic Stroke and might be the risk factors for Ischemic Stroke development, but not NOTCH3 605C>T polymorphism.

  10. This meta-analysis results did not show significant associations between polymorphisms of NOTCH3 genes and Ischemic stroke.

Mouse (Murine) Notch 3 (NOTCH3) interaction partners

  1. Knock-in mice with the R169C mutation (Notch3(R170C/R170C)) exhibited similar reductions in arterial lumen, and both TgNotch3(R169C) and Notch3(R170C/R170C) mice showed increased cerebral artery expression of Notch3 target genes.

  2. Notch3 is an important protective factor for cardiac fibrosis in a myocardial infarction model, and the protective effect of Notch3 is attributable to its action on TGF-beta1 (show TGFB1 ELISA Kits)/Smad3 (show SMAD3 ELISA Kits) signaling.

  3. Data indicate that Notch (show NOTCH1 ELISA Kits) receptors Notch1 (show NOTCH1 ELISA Kits) and Notch3 deficiency compromises pericyte function and contributes to vascular pathologies.

  4. In this study, authors use a smooth muscle-specific (show EIF3K ELISA Kits) deletion of Notch2 (show NOTCH2 ELISA Kits) together with a global Notch3 deletion to produce mice with combinations of mutant and wild-type Notch2 (show NOTCH2 ELISA Kits)/3 alleles in vascular smooth muscle cells

  5. Elevated levels of TIMP3 (show TIMP3 ELISA Kits) and vitronectin (show VTN ELISA Kits), acting downstream of Notch3(ECD) deposition, play a role in CADASIL, producing divergent influences on early CBF (show CEBPZ ELISA Kits) deficits and later white matter lesions.

  6. Mutant Notch3 accumulates in pericytes and causes progressive pericyte loss and BBB (show ALMS1 ELISA Kits) leakage in the cerebral cortex in CADASIL mouse model.

  7. Relative to air-exposed controls, ozone increased bronchoalveolar lavage fluid protein, a marker of lung permeability, in all genotypes, but significantly greater concentrations were found in Notch4 (show NOTCH4 ELISA Kits)-/- compared with wild-type and Notch3-/- mice.

  8. The mechanism of Oncostatin M (show OSM ELISA Kits) on cardiac ischemia/reperfusion injury is partly mediated by the Notch3/Akt (show AKT1 ELISA Kits) pathway.

  9. miR (show MLXIP ELISA Kits)-7a regulates the differentiation of Muller glia through the suppression of Notch3 expression.

  10. Study showed Notch3 expressed in proliferating hippocampal precursor cells and down-regulates their activation and proliferation; adult neurogenesis in CADASIL transgenic mice was altered prior to vascular abnormalities due to deficits in Notch3 signaling

Zebrafish Notch 3 (NOTCH3) interaction partners

  1. The Notch3 receptor is required earlier within the developing somite to regulate hematopoietic stem cell (HSC (show FUT1 ELISA Kits)) emergence in a non-cell-autonomous manner.

  2. 90 % of proliferating radial glia express notch1a, notch1b and notch3. In contrast, the proliferating non-glial populations of the dorsal telencephalon and hypothalamus rarely express notch3 and about half express notch1a/1b.

  3. Notch3 regulates oligodendrocyte precursor cells development and mbp (show MBP ELISA Kits) gene expression in larvae, and maintains vascular integrity in adults.

  4. new role for Notch (show NOTCH1 ELISA Kits) signaling in brain vascular development whereby Notch3 signaling promotes expansion of the brain pericyte population

  5. Notch3 activity gates neural stem cell activation in the adult pallium.

  6. Cellular correlates of Notch (show NOTCH1 ELISA Kits)-delta gene expression in the regenerating zebrafish retina.

  7. knockdown of notch3 function in notch1a mutants leads to the loss of rhombomere boundary cells and causes neuronal hyperplasia

NOTCH3 Antigen Profile

Antigen Summary

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Alternative names and synonyms associated with NOTCH3

  • notch 3 (NOTCH3) Elisa Kit
  • notch 3 (Notch3) Elisa Kit
  • notch homolog 3 (notch3) Elisa Kit
  • AW229011 Elisa Kit
  • CADASIL Elisa Kit
  • CASIL Elisa Kit
  • fa14b08 Elisa Kit
  • hpbk Elisa Kit
  • IMF2 Elisa Kit
  • N3 Elisa Kit
  • notch5 Elisa Kit
  • wu:fa14b08 Elisa Kit

Protein level used designations for Notch 3 (NOTCH3) ELISA Kits

Notch homolog 3 , neurogenic locus notch homolog protein 3 , Notch gene homolog 3

GENE ID SPECIES
4854 Homo sapiens
18131 Mus musculus
56761 Rattus norvegicus
58066 Danio rerio
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