Browse our High Mobility Group AT-Hook 1 (HMGA1) ELISA Kits

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High Mobility Group AT-Hook 1 ELISA Kits (HMGA1)
On www.antibodies-online.com are 14 High Mobility Group AT-Hook 1 (HMGA1) ELISA Kits from 7 different suppliers available. Additionally we are shipping High Mobility Group AT-Hook 1 Antibodies (129) and High Mobility Group AT-Hook 1 Proteins (20) and many more products for this protein. A total of 175 High Mobility Group AT-Hook 1 products are currently listed.
Synonyms:
AL023995, ENSMUSG00000041059, HMG-I(Y), HMG-R, HMG-Y, HMGA1, Hmga1a, Hmga1b, Hmgi, Hmgi-rs1, Hmgiy, Hmgy, wu:fb12b06, wu:fb18f11, wu:fc19f01, wu:fi38b05, zgc:85677
list all ELISA KIts Gene Name GeneID UniProt
HMGA1 111241 P17095
HMGA1 3159 P17096
HMGA1 117062 Q8K585

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Mouse (Murine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. Studies define a novel HMGA1-MMP-2 (show MMP2 ELISA Kits) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  2. Mouse embryonic fibroblasts null for the Hmga1 gene show downregulation of Bub1 (show BUB1 ELISA Kits), Bub1b (show BUB1B ELISA Kits), Mad2l1 (show MAD2L1 ELISA Kits) and Ttk SAC (show ADCY10 ELISA Kits) genes, and present several features of chromosomal instability, such as nuclear abnormalities, binucleation, micronuclei and karyotypic alterations.

  3. Taken together, our data demonstrate that miR (show MLXIP ELISA Kits)-625 suppresses cell proliferation and migration by targeting HMGA1 and suggest miR (show MLXIP ELISA Kits)-625 as a promising prognostic biomarker and a potential therapeutic target for breast cancer.

  4. Inactivation of the Cdkn2a locus cooperates with HMGA1 to drive T-cell leukemogenesis.

  5. Increased HMGA1 expression is associated with pituitary and thyroid tumors.

  6. activated HMGA1 regulates cell proliferation through the Notch1 (show NOTCH1 ELISA Kits) signaling pathway, which represents an important molecular pathway leading to leukemogenesis.

  7. Data propose that, by affecting the expression of both IGFBP protein species, HMGA1 can serve as a modulator of IGF-I (show IGF1 ELISA Kits) activity, thus representing an important novel mediator of glucose disposal.

  8. HMGA1 contributes to the neurogenic potential of neural precursor cells in the early stages of neocortical development.

  9. Elevated expression of HMGA1 is associated with the transition of prostate cancer (PCa (show ENPP1 ELISA Kits)) cells from androgen-sensitive to androgen-independent growth and plays a role in the cell growth of androgen-independent PCa (show ENPP1 ELISA Kits) cells.

  10. The data in the present study reveal a role of Hmga1 in transcriptional silencing in T cell lineages and leukemic cells.

Human High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. tissue microarray revealed that HMGA1 was expressed in thyroid carcinoma more than that in normal thyroid tissues ; expression of HMGA1 and MMP-2 (show MMP2 ELISA Kits) was identified to be positively correlated . The present study established the first link between HMGA1 and TGF-b1 in the regulation of thyroid cancer proliferation and invasion

  2. our research indicated an H19 (show NCKAP1 ELISA Kits)-miR138-HMGA1 pathway in regulating the migration and invasion of colon cancer, providing new insight for treatment of colon cancer.

  3. The results reported here indicate a critical role of HMGA1 in the development of glioblastoma multiforme; its suppression impairs proliferation and self-renewal of brain tumor stem cells

  4. miR (show MLXIP ELISA Kits)-214 expression was poor while that of HMGA1 was high in cervical and colorectal cancer tissues. miR (show MLXIP ELISA Kits)-214-re-expression or HMGA1 downregulation inhibited proliferation, migration and invasion of cancer cells while miR (show MLXIP ELISA Kits)-214 inhibition had opposite effects. miR (show MLXIP ELISA Kits)-214 was demonstrated to bind to the wild-type 3' untranslated region of HMGA1 but not with its mutant.

  5. HMGA1 is frequently expressed in cirrhotic tissues and HCCs (show HCCS ELISA Kits) and its expression is associated with high Edmondson grade and worse prognosis in HCC (show FAM126A ELISA Kits).

  6. Studies define a novel HMGA1-MMP-2 (show MMP2 ELISA Kits) pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  7. HMGA1 may function as an oncogene (show RAB1A ELISA Kits) and modulate endometrial cancer cell migration and invasion by activating Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway.

  8. Increased HMGA1 in pulmonary arterial endothelial cells resulting from dysfunctional BMPr2 (show BMPR2 ELISA Kits) signaling can transition endothelium to smooth muscle-like cells associated with pulmonary arterial hypertension.

  9. in splenic hemangioma with t(3;6)(q26;p21 (show CDKN1A ELISA Kits)), the entire coding region of HMGA1 comes under the control of the TBL1XR1 (show TBL1XR1 ELISA Kits) promoter, bringing about dysregulation of HMGA1

  10. This is the first report for the association between HMGA1 and S100A13 (show S100A13 ELISA Kits) expression in the modulation of thyroid cancer growth and invasion.

Pig (Porcine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. distinct loci exist for growth and fatness in the two populations and identified HMGA1 and PLAG1 (show PLAG1 ELISA Kits) as strong candidate genes on SSC7 and SSC4, respectively.

  2. Characterization of polymorphisms in the HMGA1 gene in relation to growth and fat deposition.

Cow (Bovine) High Mobility Group AT-Hook 1 (HMGA1) interaction partners

  1. HMGA1 likely regulates certain aspects of the BoHV-1 latency-reactivation cycle.

High Mobility Group AT-Hook 1 (HMGA1) Antigen Profile

Antigen Summary

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with High Mobility Group AT-Hook 1 (HMGA1)

  • high mobility group AT-hook I, related sequence 1 (Hmga1-rs1) Elisa Kit
  • high mobility group protein HMG-I/HMG-Y (TSC_c24220) Elisa Kit
  • high mobility group AT-hook 1a (hmga1a) Elisa Kit
  • high mobility group AT-hook 1 (HMGA1) Elisa Kit
  • high mobility group AT-hook 1 (Hmga1) Elisa Kit
  • high mobility group AT-hook 1 (Hmg-i) Elisa Kit
  • AL023995 Elisa Kit
  • ENSMUSG00000041059 Elisa Kit
  • HMG-I(Y) Elisa Kit
  • HMG-R Elisa Kit
  • HMG-Y Elisa Kit
  • HMGA1 Elisa Kit
  • Hmga1a Elisa Kit
  • Hmga1b Elisa Kit
  • Hmgi Elisa Kit
  • Hmgi-rs1 Elisa Kit
  • Hmgiy Elisa Kit
  • Hmgy Elisa Kit
  • wu:fb12b06 Elisa Kit
  • wu:fb18f11 Elisa Kit
  • wu:fc19f01 Elisa Kit
  • wu:fi38b05 Elisa Kit
  • zgc:85677 Elisa Kit

Protein level used designations for HMGA1

high mobility group protein HMG-I/HMG-Y , HMG-I(Y) , high mobility group protein A1 , high mobility group AT-hook protein 1 , high mobility group AT-hook 1 , high-mobility group (nonhistone chromosomal) protein isoforms I and Y , high mobility group protein R , nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y , high mobility group HMGA1A , high mobility group HMGA1B , non-histone protein , high-mobility group AT-hook 1 , high mobility group protein I , High mobility group AT-hook protein 1 , High mobility group protein A1 , high mobility group-I protein

GENE ID SPECIES
111241 Mus musculus
10178543 Thermus scotoductus SA-01
406447 Danio rerio
705105 Macaca mulatta
746594 Pan troglodytes
3159 Homo sapiens
442946 Canis lupus familiaris
100157848 Sus scrofa
618849 Bos taurus
15361 Mus musculus
117062 Rattus norvegicus
378795 Gallus gallus
100689040 Cricetulus griseus
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