Browse our G Protein-Coupled Receptor 172A Proteins (GPR172A)

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G Protein-Coupled Receptor 172A Proteins (GPR172A)
On are 3 G Protein-Coupled Receptor 172A (GPR172A) Proteins from 2 different suppliers available. Additionally we are shipping G Protein-Coupled Receptor 172A Antibodies (19) and G Protein-Coupled Receptor 172A Kits (11) and many more products for this protein. A total of 34 G Protein-Coupled Receptor 172A products are currently listed.
2010003P03Rik, BVVLS2, BXR, D15Ertd747e, GPCR41, GPCR42, GPR172A, Gpr172b, hRFT3, mRFT1, ONR1, PAR, Par-2, PAR1, PAR2, PARq, PRR, PXR, RFT3, RFVT2, SAR, SXR
list all proteins Gene Name GeneID UniProt
GPR172A 79581 Q9HAB3
GPR172A 116677 Q63645
GPR172A 52710 Q9D8F3

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G Protein-Coupled Receptor 172A Proteins (GPR172A) by Origin

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More Proteins for G Protein-Coupled Receptor 172A Interaction Partners

Human G Protein-Coupled Receptor 172A (GPR172A) interaction partners

  1. In intrahepatic cholestasis of pregnancy, gene silencing of miR (show MLXIP Proteins)-148a upregulated PXR (show NR1I2 Proteins) expression which was inhibited by estradiol in liver cells. miR (show MLXIP Proteins)-148a may be involved in the estrogen induction in ICP via PXR (show NR1I2 Proteins) signaling. MRP3 (show ABCC3 Proteins) may be involved.

  2. this study shows that PXR (show NR1I2 Proteins) augments Mycobacterium tuberculosis survival inside the host macrophages by promoting the foamy macrophage formation and abrogating phagolysosomal fusion, inflammation, and apoptosis

  3. PXR (show NR1I2 Proteins) is a potential biomarker for predicting outcome and activates MRP3 (show ABCC3 Proteins) transcription by directly binding to its promoter resulting in an increased L-OHP efflux capacity, and resistance to L-OHP or platinum drugs in CRC (show CALR Proteins).

  4. A novel SLC52A2 mutation identified in a family with spinocerebellar ataxia with blindness and deafness.

  5. This is the first time an association between NR1I2 (show NR1I2 Proteins) polymorphism and time of progression to AIDS is reported and supports an apparent relationship between the gene in the immune response and identifies another genetic factor influencing AIDS progression.

  6. MD simulations further revealed that the presence of small molecule at allosteric site disrupts the LBD dynamics and locks the LBD in a "tightly-contracted" conformation. The molecular details provided here could guide new structural studies to understand PXR (show NR1I2 Proteins) activation and antagonism.

  7. Extracellular granzyme K (show GZMK Proteins) mediates endothelial activation through the cleavage of PAR-1 (show MARK2 Proteins).

  8. Pregnane X receptor interacts with liver X receptor to regulate expression of SMPDL3A in primary hepatocytes.

  9. 66034T/C polymorphism of the human pregnane X receptor (show NR1I2 Proteins) (hPXR) is potential risk factor for drug-resistant epilepsy.

  10. The data suggest that some of the natural PXR (show NR1I2 Proteins) variants may have adverse physiological consequences owing to its influence on the expression levels and functional output of drug-metabolizing enzymes and transporters.

Mouse (Murine) G Protein-Coupled Receptor 172A (GPR172A) interaction partners

G Protein-Coupled Receptor 172A (GPR172A) Protein Profile

Protein Summary

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with G Protein-Coupled Receptor 172A (GPR172A)

  • solute carrier family 52 (riboflavin transporter), member 2 (SLC52A2)
  • G protein-coupled receptor 172A (GPR172A)
  • coagulation factor II (thrombin) receptor-like 1 (F2rl1)
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2)
  • solute carrier protein 52, member 2 (Slc52a2)
  • 2010003P03Rik protein
  • BVVLS2 protein
  • BXR protein
  • D15Ertd747e protein
  • GPCR41 protein
  • GPCR42 protein
  • GPR172A protein
  • Gpr172b protein
  • hRFT3 protein
  • mRFT1 protein
  • ONR1 protein
  • PAR protein
  • Par-2 protein
  • PAR1 protein
  • PAR2 protein
  • PARq protein
  • PRR protein
  • PXR protein
  • RFT3 protein
  • RFVT2 protein
  • SAR protein
  • SXR protein

Protein level used designations for GPR172A

G protein-coupled receptor 172A , PERV-A receptor 1 , porcine endogenous retrovirus A receptor 1 , putative G-protein coupled receptor GPCR41 , riboflavin transporter 3 , solute carrier family 52, riboflavin transporter, member 2 , Proteinase-activated receptor-2 G protein-coupled receptor 11 , Proteinase-activated receptor-2, G protein-coupled receptor 11 , coagulation factor II receptor-like 1 , proteinase-activated receptor 2 , thrombin receptor-like 1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor , G protein-coupled receptor 172B , PERV-A receptor 2 homolog , porcine endogenous retrovirus A receptor 2 homolog , riboflavin transporter 1

79581 Homo sapiens
464461 Pan troglodytes
701712 Macaca mulatta
100596295 Nomascus leucogenys
116677 Rattus norvegicus
8856 Homo sapiens
52710 Mus musculus
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