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Browse our E2F1 (E2F1) ELISA Kits

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E2F Transcription Factor 1 ELISA Kits (E2F1)
On are 18 E2F Transcription Factor 1 (E2F1) ELISA Kits from 7 different suppliers available. Additionally we are shipping E2F1 Antibodies (379) and E2F1 Proteins (7) and many more products for this protein. A total of 432 E2F1 products are currently listed.
ATE2FB, CG6376, dE2f, de2f1, def21, DmE2F-1, Dmel\\CG6376, Dp, drosE2F1, DRTF1/E2F, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, e2f, E2F-1, e2f1, E2FB, E2FB TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR-1 E2F1, E2F transcription factor 1, Evar(3)164, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729, mKIAA4009, RBAP1, RBBP3, RBP3, xE2F
list all ELISA KIts Gene Name GeneID UniProt
E2F1 1869 Q01094
E2F1 13555 Q61501
E2F1 399489  

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More ELISA Kits for E2F1 Interaction Partners

Fruit Fly (Drosophila melanogaster) E2F Transcription Factor 1 (E2F1) interaction partners

  1. specific alternate transcripts of activator E2F (show E2F2 ELISA Kits), dE2F1, may have a dual function on cell cycle progression and cannot simply be viewed as a pro-proliferative transcription factor

  2. These findings identify a key function of E2F in skeletal muscle required for animal viability, and illustrate how the cell cycle regulator is repurposed in post-mitotic cells.

  3. Mechanistically, miR (show MYLIP ELISA Kits)-998 operates by repressing dCbl, a negative regulator of EGFR (show EGFR ELISA Kits) signaling. Significantly, dCbl is a critical target of miR (show MYLIP ELISA Kits)-998 since dCbl phenocopies the effects of miR (show MYLIP ELISA Kits)-998 on dE2f1-dependent apoptosis in rbf (show ATP5I ELISA Kits) mutants

  4. also demonstrated that an optimum level of dLin52 is needed for dE2F1/2 activity on the hid promoter

  5. Results show that regulation of e2f1 and PCNA by DREF in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  6. Loss of dE2F compromises mitochondrial function.

  7. Data propose that the interaction between ORC5 and dE2F1 may reflect a feedback mechanism between replication initiation proteins and dE2F1 that ensures that proliferating cells maintain a robust level of replication proteins for the next cell cycle.

  8. results suggest that E2F/DP complexes are essential for all genomic targeting of RBF1

  9. Inappropriate accumulation of E2f1 protein during S phase triggers the elimination of potentially hyperplastic cells via apoptosis in order to ensure normal development of rapidly proliferating tissues.

  10. endocycles of Drosophila are driven by a molecular oscillator in which the E2F1 transcription factor promotes CycE (show CCNE1 ELISA Kits) expression and S-phase initiation, S-phase then activates the CRL4(CDT2) ubiquitin ligase, and this in turn mediates the destruction of E2F1

Human E2F Transcription Factor 1 (E2F1) interaction partners

  1. In NSCLC patients, E2F1 expression was significantly correlated with age, sex, and tumor stage. E2F1 and E2F2 (show E2F2 ELISA Kits) overexpression showed a significant association with poor prognosis.

  2. By targeting genes involved in controlling pRb (show RB1 ELISA Kits)/E2F1 activity, miR (show MLXIP ELISA Kits)-449a regulates cell cycle progression and apoptosis and consequently enhances the radiosensitivity of PC-3 (show PCSK1 ELISA Kits) cells. Thus, miR (show MLXIP ELISA Kits)-449a, as a miRNA component of the Rb pathway, promotes the radiosensitivity of PC-3 (show PCSK1 ELISA Kits) cells through regulating pRb (show RB1 ELISA Kits)/E2F1.

  3. E2F1 was confirmed as a direct target of miR (show MLXIP ELISA Kits)-622.

  4. the E2F1-mediated electron transport chain-dependent mechanism has emerged as the regulatory mechanism of cell cycle progression in breast cancer cells

  5. Integrative genomic analyses confirm that E2F4 (show E2F4 ELISA Kits) or E2F1 expression level is high in liposarcoma patients which associate with unfavorable prognosis.

  6. Chk1's (show CHEK1 ELISA Kits) expression is controlled by p53 (show TP53 ELISA Kits) and RB/E2F1 at the transcriptional level.

  7. Study found that E2F1 is overexpression in prostate cancer (PCa (show FLVCR1 ELISA Kits)) tissues and significantly associated with high Gleason score. These results suggest that E2F1 may promote tumor cell invasion and migration through the regulation of CD147 in PCa (show FLVCR1 ELISA Kits) cells.

  8. Our findings define an intricate E2F1-dependent mechanism by which Id1 increases thymidylate synthase and IGF2 expressions to promote cancer chemoresistance. The Id1-E2F1-IGF2 regulatory axis has important implications for cancer prognosis and treatment.

  9. Expression of Kv10.1 (show KCNH1 ELISA Kits) driven by phosphorylated Rb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

  10. Data suggest that the SNP rs2853669 variant induces telomerase reverse transcriptase (TERT (show TERT ELISA Kits)) transcription levels by blocking E2F1 transcription factor (E2F1) binding to its promoter.

Mouse (Murine) E2F Transcription Factor 1 (E2F1) interaction partners

  1. Expression of Kv10.1 (show KCNG3 ELISA Kits) driven by phosphorylated Rb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

  2. Spinal cord injury-induced activation of E2F1-2 mediates cell cycle activation, contributing to gliopathy and neuronal/tissue loss associated with motor impairments and post-traumatic hyperesthesia.

  3. In the initial stage of myocyte differentiation, transcription of the YB-1 (show YBX1 ELISA Kits) gene was regulated by E2F1 and Sp1 (show SP1 ELISA Kits), and was then gradually replaced under the control of both MyoD (show MYOD1 ELISA Kits) and myogenin (show MYOG ELISA Kits).

  4. Protease Omi (show HTRA2 ELISA Kits) facilitates neurite outgrowth by cleaving the transcription factor E2F1 in differentiated neuroblastoma (show ARHGEF16 ELISA Kits) cells; E2F1 is a substrate of Omi (show HTRA2 ELISA Kits).

  5. accumulating E2f1 progressively recruits a Pontin/Reptin (show RUVBL2 ELISA Kits) complex to open the chromatin conformation at E2f target genes and amplifies the E2f transcriptional response.

  6. A role for E2F1 and E2F2 (show E2F2 ELISA Kits) as suppressors of replicative stress in differentiating cells, and the existence of a robust E2F-p53 (show TP53 ELISA Kits) regulatory axis in tissue homeostasis enabling and tumorigenesis preventing is shown.

  7. E2F1 promotes apoptosis of spermatogonia during the first wave of spermatogenesis, is involved in the maintenance of the spermatogonial stem cell pool in the adult and inhibits apoptosis of the meiotic germ cells.

  8. Data (including data from studies in knockout/transgenic mice) suggest CDKN1B (show CDKN1B ELISA Kits)-RB1 (show RB1 ELISA Kits)-E2F1 (cyclin-dependent kinase inhibitor 1B (show CDKN1B ELISA Kits)-retinoblastoma 1 (show RB1 ELISA Kits)-E2F1) pathway is essential for SSC (show CYP11A1 ELISA Kits) (spermatogonial stem cell) self-renewal/protection against genomic damage.

  9. Conditional knockout of Poh1 (show PSMD14 ELISA Kits) alleles results in reduced E2F1 expression in primary mouse liver cells.

  10. E2F1 negatively regulates both Ogt (show OGT ELISA Kits) and Mgea5 (show MGEA5 ELISA Kits) expression in an Rb1 (show RB1 ELISA Kits) protein-dependent manner.

Xenopus laevis E2F Transcription Factor 1 (E2F1) interaction partners

  1. Xphb1 represses E2F1 activity.

Arabidopsis thaliana E2F Transcription Factor 1 (E2F1) interaction partners

  1. SIM (show SIM2 ELISA Kits) and SMR1 are involved in hyperphosphorylation of the cell-cycle regulator RBR1 and overexpression of E2F target genes.

  2. S6K1 interacts with retinoblastoma protein RBR via its N-terminal RBR binding motif, promotes its nuclear localization and consequent RBR-dependent repression of cell cycle genes through transcription factor E2FB.

  3. The Arabidopsis (Arabidopsis thaliana) DEL1 gene was identified as a transcriptional target of the classical E2Fb and E2Fc transcription factors.

  4. The authors found that S6K1 associates with the Retinoblastoma-related 1 (RBR1)-E2FB complex and this is partly mediated by its N-terminal LVxCxE motif.

  5. Results suggest that E2FB is one of the key targets for auxin to determine whether cells proliferate or whether they exit the cell cycle, enlarge, and endoreduplicate their DNA.

  6. AtE2Fa and AtE2Fb have specific expression patterns and may play similar but distinct roles during cell cycle progression.

E2F1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Alternative names and synonyms associated with E2F1

  • E2F transcription factor (E2f) Elisa Kit
  • E2F transcription factor 1 (E2F1) Elisa Kit
  • E2F transcription factor 1 (E2f1) Elisa Kit
  • E2F transcription factor 1 (e2f1) Elisa Kit
  • ATE2FB Elisa Kit
  • CG6376 Elisa Kit
  • dE2f Elisa Kit
  • de2f1 Elisa Kit
  • def21 Elisa Kit
  • DmE2F-1 Elisa Kit
  • Dmel\\CG6376 Elisa Kit
  • Dp Elisa Kit
  • drosE2F1 Elisa Kit
  • DRTF1/E2F Elisa Kit
  • E(Sev-CycE)3A Elisa Kit
  • E(var)3-93E Elisa Kit
  • E(var)3-95E Elisa Kit
  • E(var)93E Elisa Kit
  • e2f Elisa Kit
  • E2F-1 Elisa Kit
  • e2f1 Elisa Kit
  • E2FB Elisa Kit
  • E2F transcription factor 1 Elisa Kit
  • Evar(3)164 Elisa Kit
  • l(3)07172 Elisa Kit
  • l(3)j3B1 Elisa Kit
  • l(3)j3C2 Elisa Kit
  • l(3)rM729 Elisa Kit
  • mKIAA4009 Elisa Kit
  • RBAP1 Elisa Kit
  • RBBP3 Elisa Kit
  • RBP3 Elisa Kit
  • xE2F Elisa Kit

Protein level used designations for E2F1

CG6376-PA , CG6376-PB , CG6376-PC , CG6376-PD , E2-promoter binding factor , E2f-PA , E2f-PB , E2f-PC , E2f-PD , PBR3 , PRB-binding protein E2F-1 , RBAP-1 , RBBP-3 , retinoblastoma-associated protein 1 , retinoblastoma-binding protein 3 , transcription factor E2F1 , E2F-1 transcription factor , E2F-1

42550 Drosophila melanogaster
100069192 Equus caballus
1869 Homo sapiens
13555 Mus musculus
485839 Canis lupus familiaris
535369 Bos taurus
458184 Pan troglodytes
100036852 Xenopus laevis
396142 Gallus gallus
399489 Rattus norvegicus
100729531 Cavia porcellus
832283 Arabidopsis thaliana
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