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Browse our anti-HMGB1 (HMGB1) Antibodies

Full name:
anti-High-Mobility Group Box 1 Antibodies (HMGB1)
On are 451 High-Mobility Group Box 1 (HMGB1) Antibodies from 38 different suppliers available. Additionally we are shipping HMGB1 Kits (68) and HMGB1 Proteins (60) and many more products for this protein. A total of 602 HMGB1 products are currently listed.
Ac2-008, amphoterin, DEF, HMG-1, Hmg1, HMG3, Hmgb1, ik:tdsubc_1a5, p30, SBP-1, wu:fb23c02, xx:tdsubc_1a5, zgc:56110, zgc:77104
list all antibodies Gene Name GeneID UniProt
HMGB1 3146 P09429
HMGB1 15289 P63158
HMGB1 25459 P63159

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All available anti-HMGB1 Antibodies

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Top referenced anti-HMGB1 Antibodies

  1. Human Monoclonal HMGB1 Primary Antibody for FACS, ICC - ABIN4899428 : Liou, Adler, Keogh, Li, Jensen, Walsh, Packer, Clark, Carveth, Chen, Rogers, Lane, Moore, Sturrock, Paine, Cox, Hoidal: Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis. in PLoS ONE 2012 (PubMed)
    Show all 13 references for ABIN4899428

  2. Cow (Bovine) Polyclonal HMGB1 Primary Antibody for ELISA, FACS - ABIN250703 : Barlan, Griffin, McGuire, Wiethoff: Adenovirus membrane penetration activates the NLRP3 inflammasome. in Journal of virology 2010 (PubMed)
    Show all 13 references for ABIN250703

  3. Human Polyclonal HMGB1 Primary Antibody for IF (p), IHC (p) - ABIN671616 : Zhao, Hu, Sun, Sun: The high mobility group box 1 protein of Sciaenops ocellatus is a secreted cytokine that stimulates macrophage activation. in Developmental and comparative immunology 2011 (PubMed)
    Show all 7 references for ABIN671616

  4. Human Monoclonal HMGB1 Primary Antibody for WB - ABIN1449284 : Wen, Huang, Johnson, Reeck: A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. in Nucleic acids research 1989 (PubMed)
    Show all 3 references for ABIN1449284

  5. Human Polyclonal HMGB1 Primary Antibody for ELISA, WB - ABIN1533598 : Ferrari, Finelli, Rocchi, Bianchi: The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. in Genomics 1996 (PubMed)
    Show all 2 references for ABIN1533598

  6. Cow (Bovine) Polyclonal HMGB1 Primary Antibody for WB - ABIN2776383 : Messmer, Yang, Telusma, Knoll, Li, Messmer, Tracey, Chiorazzi: High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)

  7. Cow (Bovine) Polyclonal HMGB1 Primary Antibody for WB - ABIN2780400 : Bruneel, Labas, Mailloux, Sharma, Royer, Vinh, Pernet, Vaubourdolle, Baudin: Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. in Proteomics 2005 (PubMed)

  8. Cow (Bovine) Polyclonal HMGB1 Primary Antibody for WB - ABIN2780399 : Straino, Di Carlo, Mangoni, De Mori, Guerra, Maurelli, Panacchia, Di Giacomo, Palumbo, Di Campli, Uccioli, Biglioli, Bianchi, Capogrossi, Germani: High-mobility group box 1 protein in human and murine skin: involvement in wound healing. in The Journal of investigative dermatology 2008 (PubMed)

  9. Human Monoclonal HMGB1 Primary Antibody for WB - ABIN1107584 : Taguchi, Blood, del Toro, Canet, Lee, Qu, Tanji, Lu, Lalla, Fu, Hofmann, Kislinger, Ingram, Lu, Tanaka, Hori, Ogawa, Stern, Schmidt: Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. in Nature 2000 (PubMed)

More Antibodies against HMGB1 Interaction Partners

Human High-Mobility Group Box 1 (HMGB1) interaction partners

  1. LncRNA TUG1 knockdown enhances radiosensitivity of bladder cancer by suppressing HMGB1 expression.

  2. 2-O, 3-O desulfated heparin inhibited HMGB1 release, at least in part, by direct molecular inhibition of p300 HAT (show EP300 Antibodies) activity.

  3. TLR4 (show TLR4 Antibodies) signaling in HMGB1 mediated the suppressive function of Treg cells through the activation of the NF-kappaB (show NFKB1 Antibodies) pathway.

  4. this study shows that patients with type 2 diabetes mellitus display elevated levels of HMGB1

  5. HMGB1-induced autophagy could maintain survival and function stability of peripheral regulatory T-cells from chronic hepatitis B patients

  6. The HMGB1 C-terminal tail serves as an intramolecular damper that modulates the interaction of the binding and bending B box with DNA.

  7. These results demonstrated that miR (show MLXIP Antibodies)-142-3p regulates starvation-induced autophagy of Non-small-cell lung cancer cells by directly downregulating HMGB1 and subsequently activating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway.

  8. TREM-1 (show TREM1 Antibodies), HMGB1 and RAGE (show AGER Antibodies) in the Shoulder Tendon: Dual Mechanisms for Inflammation Based on the Coincidence of Glenohumeral Arthritis

  9. The results demonstrated reduction of cell viability upon increasing irinotecan concentration, up-regulated high-mobility group protein B1 gene expression, and down-regulated MMP9 (show MMP9 Antibodies) mRNA.

  10. These findings demonstrate that the BRAF (show BRAF Antibodies) V600E mutation down-regulates levels of HMGB1, likely through activation of the mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) signaling pathways.

Pig (Porcine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage.

  2. high levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms

  3. HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure

Cow (Bovine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 can act as an adjuvant in modulating the bovine immune system and thus lays a foundation for using HMGB1 as an adjuvant in various bovine vaccine preparations.

  2. Single-nucleotide polymorphism in the 3'-untranslated region of the HMGB1 gene affects the binding of target bta-miR (show MYLIP Antibodies)-223 and is involved in mastitis.

  3. The mechanisms of interaction of the non-histone chromosomal protein (show HMGB2 Antibodies) HMGB1 and linker histone H1 (show H1F0 Antibodies) with DNA have been studied using circular dichroism and absorption spectroscopy.

  4. HMGB1 is able to induce considerable changes in DNA structure upon binding even when the amount of the protein directly associated with DNA is low

  5. Interaction between non-histone chromatin protein HMGB1 and linker histone H1 (show H1F0 Antibodies)

  6. HMGB-1 might play a role in the pathological thickening of subchondral bone plate/osteophyte formation.

  7. Analysis of mechanical response generated by binding of DNA-bending protein HMGB1 to single tethered 48.5 kb lambda-DNA molecules finds that compaction of DNA increases with increasing HMGB1 concentration.

  8. Thrombomoduln not only binds to HMGB1 but also aids the proteolytic cleavage of HMGB1 by thrombin (show F2 Antibodies).

Mouse (Murine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. 2-O, 3-O desulfated heparin inhibited HMGB1 release, at least in part, by direct molecular inhibition of p300 HAT (show EP300 Antibodies) activity.

  2. this study reports a novel role of HMGB1 in controlling the maintenance and function of intestine-resident group-3 innate lymphoid cells that are important innate effector cells implicated in mucosal homeostasis and inflammatory bowel diseases pathogenesis

  3. this study shows that acute hypoxia upregulates high mobility group box-1 in a time-dependent manner

  4. Macrophage-produced HMGB1 leads to aortic inflammation and acts as a trigger for CD4 (show CD4 Antibodies)(+) T-cell-produced IL-17 (show IL17A Antibodies) during abdominal aortic aneurysm formation. HMGB1 release is dependent on Nox2 (show CYBB Antibodies) activation, which can be inhibited by MSCs leading to attenuation of proinflammatory cytokines and protection against AAA (show AAAS Antibodies) formation.

  5. Lipopolysaccharide treatment significantly suppressed the acute lung injury in mice with Acute lung injury/acute respiratory distress syndrome, accompanied with significant reduction in neutrophil influx, interleukin-17 (show IL17A Antibodies), monocyte chemoattractant protein 1 (show CCL2 Antibodies), high-mobility group box 1 protein, suppressor of cytokine signaling 3 (show SOCS3 Antibodies), and surfactant protein D (SP-D (show SFTPD Antibodies)) in the lungs .

  6. On lipopolysaccharide-induced tumor necrosis factor-alpha (show TNF Antibodies) and HMGB1 expression in macrophages.

  7. these results identify PKCalpha and HMGB1 as important co-regulators involved in hydrogen peroxide-induced poly-ADP-ribose formation.

  8. metformin suppresses inflammation by inhibiting the extracellular activity of HMGB1.

  9. Platelet-derived HMGB1 mediated monocyte migration via the receptor for advanced glycation end products (RAGE (show AGER Antibodies)) and suppressed apoptosis via toll-like receptor 4 (TLR4 (show TLR4 Antibodies))-dependent activation of MAPK/ERK (show MAPK1 Antibodies) (extracellular signal-regulated kinase) in monocytes. In conclusion, we identify platelet-derived HMGB1 as a critical regulator of monocyte recruitment and apoptosis, with potential implications in disease states associated

  10. Glycyrrhizin reduces HMGB1 and is protective against P. aeruginosa-induced keratitis with a clinical isolate that is noncytotoxic.

Horse (Equine) High-Mobility Group Box 1 (HMGB1) interaction partners

  1. High mobility group box-1 and nucleosomes might have use as biomarkers for horses with gastrointestinal disease.

  2. Extracellular HMGB-1 is widespread only in synovial membrane from diseased joints in horses with osteoarthritis.

  3. Osteochondral injury was associated with a significant increase in synovial HMGB-1 concentrations in horses with joint injuries, compared with results for clinically normal horses.

Rabbit High-Mobility Group Box 1 (HMGB1) interaction partners

  1. Airway pressure release ventilation reduces bronchoalveolar lavage fluid HMGB1 levels and lung water, preserving oxygenation and systemic blood pressure in experimental acute respiratory distress syndrome.

Zebrafish High-Mobility Group Box 1 (HMGB1) interaction partners

  1. HMGB1 is a critical factor for brain development, enabling survival and proliferation of neural progenitors that will form the forebrain structures.

HMGB1 Antigen Profile

Antigen Summary

a transcriptional regulator that may play a central role in the stabilization and/or assembly of several multifunctional complexes through protein-protein interactions

Alternative names and synonyms associated with HMGB1

  • high-mobility group box 1 (hmgb1) antibody
  • high mobility group box 1 (hmgb1) antibody
  • high mobility group box 1 (HMGB1) antibody
  • high-mobility group box 1 (HMGB1) antibody
  • high mobility group box 1 (Hmgb1) antibody
  • high mobility group protein B1-like (LOC100392312) antibody
  • high mobility group protein B1-like (LOC100754755) antibody
  • high-mobility group box 1 (LOC100359149) antibody
  • high-mobility group box 1a (hmgb1a) antibody
  • HMG-box transcription factor 1 (Hbp1) antibody
  • Ac2-008 antibody
  • amphoterin antibody
  • DEF antibody
  • HMG-1 antibody
  • Hmg1 antibody
  • HMG3 antibody
  • Hmgb1 antibody
  • ik:tdsubc_1a5 antibody
  • p30 antibody
  • SBP-1 antibody
  • wu:fb23c02 antibody
  • xx:tdsubc_1a5 antibody
  • zgc:56110 antibody
  • zgc:77104 antibody

Protein level used designations for HMGB1

high-mobility group box 1 , high mobility group protein 1 , sulfoglucuronyl carbohydrate binding protein , High mobility group protein B1 , HMG-1 , high mobility group protein B1 , Amphoterin , Sulfoglucuronyl carbohydrate binding protein , high-mobility group (nonhistone chromosomal) protein 1 , non-histone protein HMG1 , amphoterin , heparin-binding protein p30 , high mobility group 1 , high mobility group protein B1-like protein , high mobility group 1 protein , high mobility group protein HMG1 , high mobility group protein B1-like , High mobility group protein 1 , high mobility group box 1 , tdsubc_1a5 , HMG box transcription factor 1 , HMG box-containing protein 1 , HMG-box containing protein 1 , high mobility group box transcription factor 1

100136339 Oncorhynchus mykiss
394834 Xenopus (Silurana) tropicalis
452518 Pan troglodytes
100137373 Papio anubis
100194543 Salmo salar
403170 Canis lupus familiaris
3146 Homo sapiens
445521 Sus scrofa
282691 Bos taurus
15289 Mus musculus
25459 Rattus norvegicus
100033873 Equus caballus
100328641 Oryctolagus cuniculus
395724 Gallus gallus
380530 Xenopus laevis
100392312 Callithrix jacchus
100754755 Cricetulus griseus
100359149 Oryctolagus cuniculus
321622 Danio rerio
27080 Rattus norvegicus
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