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Browse our HRAS Proteins (HRAS)

Full name:
V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog Proteins (HRAS)
On are 20 V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) Proteins from 9 different suppliers available. Additionally we are shipping HRAS Antibodies (127) and HRAS Kits (15) and many more products for this protein. A total of 171 HRAS products are currently listed.
AI929937, C-BAS/HAS, c-H-ras, c-Ha-ras, C-HA-RAS1, c-rasHa, CTLO, H-ras, H-RASIDX, Ha-ras, HAMSV, Harvey-ras, hras, Hras-1, HRAS1, K-ras, Ki-ras, Kras-2, Kras2, N-RAS, p21B, ras, RASH1, zgc:110250
list all proteins Gene Name GeneID UniProt
HRAS 3265 P01112
HRAS 293621 P20171
HRAS 15461 Q61411

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HRAS Proteins (HRAS) by Origin

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Top referenced HRAS Proteins

  1. Human HRAS Protein expressed in Baculovirus infected Insect Cells - ABIN2005011 : Sekiya, Fushimi, Hori, Hirohashi, Nishimura, Sugimura: Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient. in Proceedings of the National Academy of Sciences of the United States of America 1984 (PubMed)
    Show all 6 references for ABIN2005011

  2. Human HRAS Protein expressed in Escherichia coli (E. coli) - ABIN666969 : Ayllón, Rebollo: Ras-induced cellular events (review). in Molecular membrane biology 2000 (PubMed)
    Show all 2 references for ABIN666969

More Proteins for HRAS Interaction Partners

Cow (Bovine) V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) interaction partners

  1. Data demonstrate that H-Ras activation is important in the activation of the specific signaling events leading to the accelerated retinal capillary cell apoptosis in hyperglycemic conditions.

  2. Activation of H-Ras and its downstream signaling pathway in the retina and its vasculature could be under the control of superoxide, and H-Ras activation in diabetes can be prevented by inhibiting superoxide accumulation.

  3. Thrombospondin 1 (show THBS1 Proteins), fibronectin (show FN1 Proteins), and vitronectin (show VTN Proteins) are differentially dependent upon RAS, ERK1/2, and p38 (show MAPK14 Proteins) for induction of vascular smooth muscle cell chemotaxis.

Zebrafish V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) interaction partners

  1. Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish

Human V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) interaction partners

  1. Data show that Ba/F3 cells transformed with mutant HRAS protien indicated equal sensitivity towards Map kinase (show MAPK1 Proteins) kinase (MEK (show MAP2K1 Proteins)) and mTOR (show FRAP1 Proteins) serine-threonine kinase (show TLK2 Proteins) (mTOR (show FRAP1 Proteins)) inhibition.

  2. HRAS differentially influences iTBS- and PAS (show PASK Proteins)-induced LTP (show SCP2 Proteins).

  3. our data suggest roles for HRAS and EGFR (show EGFR Proteins) as drivers in a subset of poroma and porocarcinoma.

  4. Endocytosis separates EGF (show EGF Proteins) receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes.

  5. We describe extensively the tumor suppressive and oncogenic roles of miRNAs in regulation of ras oncogenes in Oral squamous cell carcinoma

  6. SHP2 (show PTPN11 Proteins) activity is elevated in astrocytes isolated from glioblastoma multiforme-prone H-Ras(12V) knock-in mice.

  7. analysis of HRAS, KRAS and NRAS (show NRAS Proteins) expression in colorectal tumor cells

  8. Nanoclustering of mutant proteins in plasma membrane dictates downstream effector recruitment, MAPK (show MAPK1 Proteins)-activity, and tumorigenic cell proliferation.

  9. Expression of flotillin-1 (show FLOT1 Proteins) was associated with H-Ras in breast cancer, especially in TNBC (p < 0.001).

  10. The RAS-binding domain of human BRAF (show BRAF Proteins) protein exhibits allosteric conformational changes upon binding HRAS.

Mouse (Murine) V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) interaction partners

  1. Findings suggest that COX-2 deletion contributes to the repression of K-ras-induced lung tumorigenesis by reducing tumor cell proliferation, decreasing the production of PGE2, and increasing the production of 13,14-dihydro-15-keto-PGE2, possibly via the MAPK (show MAPK1 Proteins) pathway.

  2. Data indicate that KrasG12D;Pdx1 (show PDX1 Proteins)-Cre mouse model enables one to monitor the progression of pancreatic cancer (PC) from the onset of precursor lesions to cancer development.

  3. in this overview are the features of various KRAS-driven genetically engineered mouse models (GEMMs) of non-small cell lung cancer--{REVIEW}

  4. Binase-KRAS interaction interferes with the function of GEFs and stabilizes the inactive GDP-bound conformation of RAS thereby inhibiting MAPK/ERK (show MAPK1 Proteins) signaling and oncogenic activity.

  5. Data show that in both GTP- and GDP-bound states of the K-Ras, the catalytic domain exhibited similar membrane orientations.

  6. our results highlight the importance of Pas1 as a tumor-modifier locus, attribute to it a novel role as a major regulator of transcription in lung tumor nodules and strengthen the candidacy of the Kras gene as the effector of this locus.

  7. demonstrated that despite having both Kras and Pik3ca (show PIK3CA Proteins) mutations at the time of tumor initiation from loss of APC (show APC Proteins)

  8. coexpression of BRAF (show BRAF Proteins)(V600E) and KRAS(G12D) in early tumorigenesis leads to negative selection due to oncogene (show RAB1A Proteins)-induced senescence

  9. CDK1 is a synthetic lethal target for KRAS mutant tumors.

  10. Kras is the unique Ras family member that plays a critical role in early B cell development and late B cell maturation (show TNFRSF17 Proteins)

HRAS Protein Profile

Protein Summary

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Alternative names and synonyms associated with HRAS

  • Harvey rat sarcoma viral oncogene homolog (hras)
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS)
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog a (hrasa)
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)
  • Harvey rat sarcoma viral oncogene homolog (HRAS)
  • Harvey rat sarcoma virus oncogene (Hras)
  • Harvey rat sarcoma virus oncogene 1 (Hras1)
  • v-Ha-ras Harvey rat sarcoma viral oncogene homolog (Hras)
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (Kras)
  • AI929937 protein
  • C-BAS/HAS protein
  • c-H-ras protein
  • c-Ha-ras protein
  • C-HA-RAS1 protein
  • c-rasHa protein
  • CTLO protein
  • H-ras protein
  • H-RASIDX protein
  • Ha-ras protein
  • HAMSV protein
  • Harvey-ras protein
  • hras protein
  • Hras-1 protein
  • HRAS1 protein
  • K-ras protein
  • Ki-ras protein
  • Kras-2 protein
  • Kras2 protein
  • N-RAS protein
  • p21B protein
  • ras protein
  • RASH1 protein
  • zgc:110250 protein

Protein level used designations for HRAS

v-Ha-ras Harvey rat sarcoma viral oncogene homolog , small G-protein H-Ras , Harvey ras 1 , p19 H-RasIDX protein , GTPase HRas (Transforming protein p21) (H-Ras-1) (c-H-ras) , xRAS1 , GTPase HRas , Transforming protein p21 , neuroblastoma ras oncogene , GTP- and GDP-binding peptide B , H-Ras-1 , Ha-Ras1 proto-oncoprotein , Ras family small GTP binding protein H-Ras , c-has/bas p21 protein , c-ras-Ki-2 activated oncogene , p21ras , transformation gene: oncogene HAMSV , transforming protein p21 , Harvey ras1 protein , Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog , H-ras 1 protein , c-Ha-ras p21 protein , c-Ha-ras transgene , transforming protein P21 , GTPase NRas , transforming protein N-Ras , c-H-ras , v-Ha-ras Harvey rat sarcoma viral oncogene-like protein , ras p21 , GTPase KRas , K-Ras 2 , Kirsten rat sarcoma oncogene 2, expressed , c-K-ras , c-Ki-ras , p21 protein

399406 Xenopus laevis
466302 Pan troglodytes
513012 Bos taurus
549757 Xenopus (Silurana) tropicalis
550286 Danio rerio
698830 Macaca mulatta
733587 Sus scrofa
100222058 Taeniopygia guttata
100227892 Taeniopygia guttata
3265 Homo sapiens
293621 Rattus norvegicus
15461 Mus musculus
100739349 Sus scrofa
100735038 Cavia porcellus
396229 Gallus gallus
403735 Canis lupus familiaris
100298939 Bos taurus
101104357 Ovis aries
16653 Mus musculus
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