B-Cell CLL/lymphoma 2 (BCL2) (Internal Region) Peptide

Details for Product No. ABIN1382198, Supplier: Log in to see
Protein Name
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2-like
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • LOC100224888
  • bcl2
  • LOC100359045
  • BCL-2
Protein Region
Internal Region
Origin
Human
17
9
8
1
Application
Blocking Peptide (BP)
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Blocked Antibody anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (Middle Region) (ABIN1030884)
Characteristics 14 amino acids near the center of human Bcl-2.
Human
Research Area Cancer, Apoptosis/Necrosis
Application Notes Bcl-2 peptide is used for blocking the activity of Bcl-2.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Bieniasz: "Intrinsic immunity: a front-line defense against viral attack." in: Nature immunology, Vol. 5, Issue 11, pp. 1109-15, 2004 (PubMed).

Sheehy, Gaddis, Choi, Malim: "Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein." in: Nature, Vol. 418, Issue 6898, pp. 646-50, 2002 (PubMed).

Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991 (PubMed).