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Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) Peptide

Details for Product No. ABIN1382324, Supplier: Log in to see
Protein Name
  • 9030414B18Rik
  • AI225830
  • C85377
  • Ern1
  • hIRE1p
  • IRE1
  • Ire1
  • Ire1a
  • IRE1a
  • Ire1alpha
  • Ire1b
  • IRE1P
  • Ire1p
  • RGD1559716
Protein Region
Internal Region
Origin
Human
7
4
3
1
1
1
Application
Blocking Peptide (BP)
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Blocked Antibody anti-ERN1 antibody (Endoplasmic Reticulum To Nucleus Signaling 1) (Middle Region) (ABIN1030962)
Characteristics 15 amino acids near the center of human IRE1p.
Human
Application Notes IRE1p peptide is used for blocking the activity of IRE1p.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, 2004 (PubMed).

Hawn, Verbon, Lettinga, Zhao, Li, Laws, Skerrett, Beutler, Schroeder, Nachman, Ozinsky, Smith, Aderem: "A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1563-72, 2003 (PubMed).

Miyoshi, Katayama, Imaizumi, Taniguchi, Mori, Hitomi, Yui, Manabe, Gomi, Yoneda, Tohyama: "Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line." in: Brain research. Molecular brain research, Vol. 85, Issue 1-2, pp. 68-76, 2001 (PubMed).

Hayashi, Smith, Ozinsky, Hawn, Yi, Goodlett, Eng, Akira, Underhill, Aderem: "The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5." in: Nature, Vol. 410, Issue 6832, pp. 1099-103, 2001 (PubMed).