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Browse our AKT3 Proteins (AKT3)

Full name:
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) Proteins (AKT3)
On www.antibodies-online.com are 18 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) Proteins from 9 different suppliers available. Additionally we are shipping AKT3 Antibodies (232) and AKT3 Kits (29) and many more products for this protein. A total of 292 AKT3 products are currently listed.
Synonyms:
AI851531, D930002M15Rik, MPPH, Nmf350, PKB-GAMMA, Pkbg, PKBgamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2
list all proteins Gene Name GeneID UniProt
AKT3 23797 Q9WUA6
AKT3 10000 Q9Y243
Rat AKT3 AKT3 29414 Q63484

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AKT3 Proteins (AKT3) by Origin

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Top referenced AKT3 Proteins

  1. Mouse (Murine) AKT3 Protein expressed in Baculovirus infected Insect Cells - ABIN2008529 : Walker, Deak, Paterson, Hudson, Cohen, Alessi: Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha. in The Biochemical journal 1998 (PubMed)

More Proteins for AKT3 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) interaction partners

  1. Downregulation of AKT3 increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4 (show S100A4 Proteins).

  2. In viable Akt (show AKT1 Proteins) three-isoforms conditional knockout mice, total Akt (show AKT1 Proteins) levels were reduced in the adult brain. They had increased levels of phosphorylated tau, GSK3alpha and PKA substrates. No significant changes in p-tau levels were found in Akt3-/-)mice.

  3. untreated Akt1 (show AKT1 Proteins) and Akt2 (show AKT2 Proteins)/Akt3 double knockout mice display significant hearing loss, indicating a role for these isoforms in normal hearing.

  4. MicroRNA-207 enhances radiation-induced apoptosis by targeting Akt3 in cochlea hair cells.

  5. Blocking Akt1 (show AKT1 Proteins) or Akt3 but not Akt2 (show AKT2 Proteins) expression prohibits cell proliferation and reprogramming.

  6. Mechanistic investigations uncovered opposing functions for different Akt (show AKT1 Proteins) isoforms in this regulation, where Akt1 (show AKT1 Proteins) promotes and Akt3 inhibits vascular tumor growth.

  7. MiR (show MLXIP Proteins)-29 modulates growth and promotes differentiation of skeletal muscle through the post-transcriptional downregulation of Akt3.

  8. AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.

  9. Findings demonstrate that N-cadherin (show CDH2 Proteins) suppresses Akt3 to promote cell motility and highlight the intricate regulation of Akt (show AKT1 Proteins) isoforms by N-cadherin (show CDH2 Proteins) during metastasis.

  10. AKT3-deficient mice have a more severe disease course than wild-type mice during experimental autoimmune encephalomyelitis (EAE), because AKT3 is necessary for proper central nervous system (CNS) cell integrity.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) interaction partners

  1. High AKT3 expression is associated with ovarian cancer.

  2. AKT3 has a role in prostate cancer proliferation through regulation of Akt, B-Raf, and TSC1/TSC2

  3. mirn424 has a role in inhibiting Akt3/E2F3 axis and tumor growth in hepatocellular carcinoma

  4. Akt1 (show AKT1 Proteins) and Akt2 (show AKT2 Proteins) activated both SREBP-1 (show SREBF1 Proteins) and SREBP-2 (show SREBF2 Proteins), whereas Akt3 upregulated SREBP-1 (show SREBF1 Proteins) to enhance hepatitis C virus translation.

  5. Flot-2 (show FLOT2 Proteins) exerts a pro-neoplastic role in NPC (show NPC1 Proteins) and is involved in tumor progression and metastasis. Moreover, Flot-2 (show FLOT2 Proteins) exerts its role through NF-kappaB (show NFKB1 Proteins) and PI3K (show PIK3CA Proteins)/Akt3 signaling.

  6. Downregulation of AKT3 increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4 (show S100A4 Proteins).

  7. These findings indicate that AKT3 upregulation may cause focal malformations of cortical development.

  8. These findings suggest a central AKT (show AKT1 Proteins)-FOXG1 (show FOXG1 Proteins)-reelin (show RELN Proteins) signaling pathway in focal malformations of cortical development and support pathway inhibitors as potential treatments or therapies for some forms of focal epilepsy.

  9. Data show that both serine/threonine phosphatases PHLPP and dephosphorylated the physiological substrates of Akt1 (show AKT1 Proteins) and Akt3 with similar efficiencies.

  10. miR (show MLXIP Proteins)-582-5p regulated the progression of hepatocellular carcinoma through directly inhibiting the expression of CDK1 (show CDK1 Proteins) and AKT3, and indirectly inhibiting the expression of cyclinD1

AKT3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with AKT3

  • thymoma viral proto-oncogene 3 (Akt3)
  • v-akt murine thymoma viral oncogene homolog 3 (AKT3)
  • v-akt murine thymoma viral oncogene homolog 3 (Akt3)
  • v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (AKT3)
  • v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (akt3)
  • AI851531 protein
  • D930002M15Rik protein
  • MPPH protein
  • Nmf350 protein
  • PKB-GAMMA protein
  • Pkbg protein
  • PKBgamma protein
  • PRKBG protein
  • RAC-gamma protein
  • RAC-PK-gamma protein
  • STK-2 protein

Protein level used designations for AKT3

PKB gamma , RAC-PK-gamma , RAC-gamma serine/threonine-protein kinase , protein kinase Akt-3 , protein kinase B gamma , RAC-gamma serine/threonine protein kinase , v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) , AKT3 kinase , protein kinase B, gamma , thymoma viral proto-oncogene 3 , v-akt murine thymoma viral oncogene 3 , protein kinase B gamma-like protein , v-akt murine thymoma viral oncogene-like 3

GENE ID SPECIES
23797 Mus musculus
10000 Homo sapiens
29414 Rattus norvegicus
442964 Canis lupus familiaris
100137872 Bos taurus
421497 Gallus gallus
100513811 Sus scrofa
100127477 Sus scrofa
100149794 Danio rerio
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