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Browse our AKT3 Proteins (AKT3)

Full name:
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) Proteins (AKT3)
On www.antibodies-online.com are 19 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) Proteins from 10 different suppliers available. Additionally we are shipping AKT3 Antibodies (268) and AKT3 Kits (21) and many more products for this protein. A total of 320 AKT3 products are currently listed.
Synonyms:
AI851531, D930002M15Rik, MPPH, Nmf350, PKB-GAMMA, Pkbg, PKBgamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2
list all proteins Gene Name GeneID UniProt
AKT3 23797 Q9WUA6
AKT3 10000 Q9Y243
Rat AKT3 AKT3 29414 Q63484

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AKT3 Proteins (AKT3) by Origin

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Top referenced AKT3 Proteins

  1. Human AKT3 Protein expressed in Baculovirus infected Insect Cells - ABIN2003366 : Walker, Deak, Paterson, Hudson, Cohen, Alessi: Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha. in The Biochemical journal 1998 (PubMed)

More Proteins for AKT3 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) interaction partners

  1. miR (show MLXIP Proteins)-15b-5p is a critical regulator of human EC proliferation and migration by targeting the AKT3 pathway.

  2. Akt3 constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (show WNK1 Proteins)/SGK1 (show SGK1 Proteins)/Cdc42 (show CDC42 Proteins) pathway.

  3. The predominant AKT (show AKT1 Proteins) isoform in the central nervous system, AKT3, induces much more robust axon regeneration than AKT1 (show AKT1 Proteins) and that activation of mTORC1 and inhibition of GSK3beta are two critical parallel pathways for AKT (show AKT1 Proteins)-induced axon regeneration.

  4. Downregulation of AKT3 increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4 (show S100A4 Proteins).

  5. In viable Akt (show AKT1 Proteins) three-isoforms conditional knockout mice, total Akt (show AKT1 Proteins) levels were reduced in the adult brain. They had increased levels of phosphorylated tau, GSK3alpha and PKA substrates. No significant changes in p-tau levels were found in Akt3-/-)mice.

  6. untreated Akt1 (show AKT1 Proteins) and Akt2 (show AKT2 Proteins)/Akt3 double knockout mice display significant hearing loss, indicating a role for these isoforms in normal hearing.

  7. MicroRNA-207 enhances radiation-induced apoptosis by targeting Akt3 in cochlea hair cells.

  8. Blocking Akt1 (show AKT1 Proteins) or Akt3 but not Akt2 (show AKT2 Proteins) expression prohibits cell proliferation and reprogramming.

  9. Mechanistic investigations uncovered opposing functions for different Akt (show AKT1 Proteins) isoforms in this regulation, where Akt1 (show AKT1 Proteins) promotes and Akt3 inhibits vascular tumor growth.

  10. MiR (show MLXIP Proteins)-29 modulates growth and promotes differentiation of skeletal muscle through the post-transcriptional downregulation of Akt3.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) interaction partners

  1. AKT3 expression is markedly upregulated in AKT (show AKT1 Proteins) inhibitor-resistant cells. Induction of AKT3 is regulated epigenetically by the bromodomain and extra terminal domain proteins. Importantly, knockdown of AKT3, but not AKT1 (show AKT1 Proteins) or AKT2 (show AKT2 Proteins), in resistant cells restores sensitivity to MK2206.

  2. miR (show MLXIP Proteins)-15b-5p is a critical regulator of human EC proliferation and migration by targeting the AKT3 pathway.

  3. Akt3 constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (show WNK1 Proteins)/SGK1 (show SGK1 Proteins)/Cdc42 (show CDC42 Proteins) pathway.

  4. partial co-localization of AKT3 with AURKB (show AURKB Proteins) was observed during anaphase. Overall, this study suggests that AKT3 could repress the antiproliferative effects of AURKi, with a novel activity particularly suppressing the aneuploidy induction.

  5. A C119S Akt3 mutant was hypomorphic for all downstream phenotypes shown by wild-type Akt3. This study documents isozyme-specific and chemical redox signal-personalized physiological responses.

  6. the mitochondrial oxygen consumption rate was significantly reduced in Akt3-knockdown cancer cell lines

  7. our findings indicate that the expression levels of P-GP (show ABCB4 Proteins), MYC (show MYC Proteins), caspase-8 (show CASP8 Proteins), and AKT3 are candidate biomarkers of cell sensitivity to PLKis.

  8. miR (show MLXIP Proteins)-29a could act as a tumor suppressor in PTC (show F9 Proteins) by targeting AKT3 and that miR (show MLXIP Proteins)-29a may potentially serve as an anti-tumor agent in the treatment of papillary thyroid carcinoma.

  9. showed that miR (show MLXIP Proteins)-20b was down-regulated in the retina and retinal endothelial cells in diabetic rats, with a correlated up-regulation of VEGF (show VEGFA Proteins) and AKT3

  10. The siRNA-induced AKT3 and PI3KCA mRNA knockdown.

AKT3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with AKT3

  • thymoma viral proto-oncogene 3 (Akt3)
  • v-akt murine thymoma viral oncogene homolog 3 (AKT3)
  • v-akt murine thymoma viral oncogene homolog 3 (Akt3)
  • v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (AKT3)
  • v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (akt3)
  • AI851531 protein
  • D930002M15Rik protein
  • MPPH protein
  • Nmf350 protein
  • PKB-GAMMA protein
  • Pkbg protein
  • PKBgamma protein
  • PRKBG protein
  • RAC-gamma protein
  • RAC-PK-gamma protein
  • STK-2 protein

Protein level used designations for AKT3

PKB gamma , RAC-PK-gamma , RAC-gamma serine/threonine-protein kinase , protein kinase Akt-3 , protein kinase B gamma , RAC-gamma serine/threonine protein kinase , v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) , AKT3 kinase , protein kinase B, gamma , thymoma viral proto-oncogene 3 , v-akt murine thymoma viral oncogene 3 , protein kinase B gamma-like protein , v-akt murine thymoma viral oncogene-like 3

GENE ID SPECIES
23797 Mus musculus
10000 Homo sapiens
29414 Rattus norvegicus
442964 Canis lupus familiaris
100137872 Bos taurus
421497 Gallus gallus
100513811 Sus scrofa
100127477 Sus scrofa
100149794 Danio rerio
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