Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Cloning and functional analysis of the bim gene.
LA provoked a down regulation of two anti-apoptotic proteins, Mcl-1 (show MCL1 ELISA Kits) and Bcl-xL (show BCL2L1 ELISA Kits) protein and a strong induction of the BH3-only (show BBC3 ELISA Kits) protein Bim.
JNK/c-Jun activation and BIM induction is a late pro-apoptotic response of glioma cells treated with alkylating anticancer drugs.
analysis of the intricate network regulating Bim activity and its involvement in physiological and pathophysiological processes [review]
Review/Meta-analysis: BIM deletion polymorphism was associated with poor response in NSCLC patients who received EGFR (show EGFR ELISA Kits)-TKIs treatment.
Low expression of pro-apoptotic Bim protein in in Waldenstrom macroglobulinemia.
miR (show MLXIP ELISA Kits)-192 directly targeted 3'-UTR (show UTS2R ELISA Kits) of Bim gene, and inhibited its protein expression in esophageal squamous carcinoma cells, suppressing apoptosis and promoting proliferation.
The current study demonstrated that the BH3-only (show BBC3 ELISA Kits) protein, Bim, might regulate a subset of inflammatory cells in the gastric mucosa during H. pylori-mediated gastritis.
The BIM deletion polymorphism did not predict clinical outcomes in patients with NSCLC.
Jmjd3 (show Kdm6b ELISA Kits) regulates osteoblast apoptosis through targeting Bcl-2 (show BCL2 ELISA Kits) expression and Bim phosphorylation.
Taken together, these results show that CHAF1A (show CHAF1A ELISA Kits) contributes to the proliferation of glioblastoma cells and may be developed as a de novo drug target and prognosis biomarker of glioblastoma.
Consistent with a contribution of BCL2 (show BCL2 ELISA Kits) family proteins to the second wave of cell death during involution, loss of Bim reduced the number of apoptotic cells in this irreversible phase
Bcl2 interacting mediator of cell death (Bim) and Bcl2 modifying factor (Bmf (show BMF ELISA Kits)), mediate apoptosis in the context of TACI (show TNFRSF13B ELISA Kits)-Ig overexpression that effectively neutralizes BAFF (show TNFSF13B ELISA Kits) as well as APRIL.
these results indicate that 1alpha,25(OH)2D3 and TX 527 trigger apoptosis by Bim protein increase which turns into the activation of caspase-3 (show CASP3 ELISA Kits) in SVEC and vGPCR cells
miR (show MLXIP ELISA Kits)-155 regulates the delicate balance between PAK1 (show PAK1 ELISA Kits)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.
The findings reveal an essential role for TRIM33 (show TRIM33 ELISA Kits) in preventing apoptosis in B lymphoblastic leukemia by interfering with enhancer-mediated Bim activation.
BIM deficiency prevents diabetes in NOD mice by diverting thymocytes to Treg cells via reduced thymic deletion.
with age, enhanced ICOS (show ICOS ELISA Kits) expression on eTregs likely limits Bim expression via activation of the PI3K/Akt (show AKT1 ELISA Kits)/FOXO (show FOXO3 ELISA Kits) pathway, promoting eTreg survival.
SNAI2 (show SNAI2 ELISA Kits)-driven BIM-induced apoptosis may temper metastasis by governing the survival of disseminating breast tumor cells.
Hsp27 (show HSPB1 ELISA Kits) binding to the 3'UTR (show UTS2R ELISA Kits) of Bim mRNA prevents neuronal death during oxidative stress-induced (show SQSTM1 ELISA Kits) injury.
BIMEL expression is regulated in porcine cumulus cells by oocyte secreted factor GDF9 (show GDF9 ELISA Kits).
It was concluded that apoptotic cumulus cells, in which BIM(EL) up-regulation was involved, accelerated oocyte aging and degeneration in vitro via a paracrine action.
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
, Bcl-2 interacting mediator of cell death
, bcl-2 interacting mediator of cell death
, bcl-2 interacting protein Bim
, bcl-2-like protein 11
, bcl-2-related ovarian death agonist
, Bcl2 interacting mediator of cell death
, bcl2-interacting mediator of cell death
, Bcl-2 related apoptotic gene product BimL
, bcl-2-related ovarian death protein