Browse our BIM (BCL2L11) ELISA Kits

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BCL2-Like 11 (Apoptosis Facilitator) ELISA Kits (BCL2L11)
On are 19 BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) ELISA Kits from 10 different suppliers available. Additionally we are shipping BIM Antibodies (339) and BIM Proteins (12) and many more products for this protein. A total of 390 BIM products are currently listed.
1500006F24Rik, BAM, Bim, BIMEL, BimL, Bod
list all ELISA KIts Gene Name GeneID UniProt
BCL2L11 10018 O43521
BCL2L11 12125 O54918
BCL2L11 64547 O88498

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More ELISA Kits for BIM Interaction Partners

Zebrafish BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) interaction partners

  1. Cloning and functional analysis of the bim gene.

Human BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) interaction partners

  1. BIM is associated with favorable prognostic markers for prediction of disease-free survival and overall survival in cervical cancer.

  2. this study shows that BIM deletion polymorphisms are associated with a poor clinical response to erlotinib and represents an independent prognostic factor for patients with EGFR (show EGFR ELISA Kits) positive non-small-cell lung cancer

  3. The Bim deletion polymorphism was found to be associated with primary resistance to crizotinib in patients with ALK (show ALK ELISA Kits) fusion-positive NSCLC.

  4. increased apoptosis resistance was associated with significantly reduced up-regulation of proapoptotic Bim in T cells from patients with primary sclerosing cholangitis.

  5. Results suggest that valproic acid (VPA) reduces paraoxonase 2 (PON2 (show PON2 ELISA Kits)) expression in glioblastoma multiforme (GBM) cells, which in turn increases reactive oxygen species (ROS (show ROS1 ELISA Kits)) production and induces Bim protein production that inhibits cancer progression via the PON2 (show PON2 ELISA Kits)-Bim cascade.

  6. Little difference in Bim expression among CD20 (show MS4A1 ELISA Kits)+ cells was seen between tonsil primary follicles, tonsil germinal centers, and lupus nephritis renal tissue. The frequency of Bim-positive cells among CD4 (show CD4 ELISA Kits)+ lymphocytes was significantly lower in lupus nephritis kidneys compared to tonsil controls.

  7. Inhibition of mTORC1-mediated 4EBP1 (show EIF4EBP1 ELISA Kits) phosphorylation leads to decreased expression of c-MYC (show MYC ELISA Kits) and subsequent upregulation of the proapoptotic BCL2 (show BCL2 ELISA Kits) family member PUMA (show BBC3 ELISA Kits), whereas inhibition of mTORC2 (show CRTC2 ELISA Kits) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1 (show EGR1 ELISA Kits)) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 locus encoding BIM.

  8. miR (show MLXIP ELISA Kits)-423-3p activates oncogenic and Beclin-1 (show BECN1 ELISA Kits)-dependent autophagy and promotes GC progression by reducing the expression of Bim. The newly identified miR (show MLXIP ELISA Kits)-423-3p-Bim axis might be a potential therapeutic target in GC.

  9. activation of the PI3K (show PIK3CA ELISA Kits) pathway does not suppress activation of the ARF or BIM gene by over-expressed E2F1 (show E2F1 ELISA Kits)

  10. have shown that Bim protein expression in CM is an independent predictor for advanced disease confirming that this pro-apoptotic BH3-only (show BBC3 ELISA Kits) protein might be a potent biomarker and promising therapeutic target

Mouse (Murine) BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) interaction partners

  1. understanding the cell autonomous role Bim plays in the retinal vascular homeostasis will give us new insight into how to modulate pathological retinal neovascularization and vessel regression to preserve vision

  2. The central role of Bim-dependent apoptosis in Buruli Ulcer pathogenesis

  3. we found a temporal and tissue-specific role for Bim in limiting thymic agonist selection of CD8alphaalpha precursors and their TCRbeta repertoire, but not in the maintenance of CD8alphaalpha intraepithelial lymphocytes in the intestine.

  4. loss of the BH3-only (show BBC3 ELISA Kits) protein BIM accelerated lymphoma development in p53 (show TP53 ELISA Kits)-deficient mice. This process was negated by concomitant loss of RAG1 (show RAG1 ELISA Kits)/2-mediated antigen receptor gene rearrangement.

  5. Overexpression of miR (show MLXIP ELISA Kits)-29 or miR (show MLXIP ELISA Kits)-24 is sufficient to inhibit the induction of Bim and Puma (show BBC3 ELISA Kits) in young sympathetic neurons.

  6. the activation of ERK5 (show MAPK7 ELISA Kits)-AKT (show AKT1 ELISA Kits)-FoxO3a (show FOXO3 ELISA Kits) signaling pathways by fluid shear stress resulted in a decreased expression of FasL (show FASL ELISA Kits) and Bim and an inhibition of caspase-3 (show CASP3 ELISA Kits) activation, which exerts a protective effect that prevents osteoblasts from apoptosis.

  7. long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

  8. Results indicate that upregulation of miR (show MLXIP ELISA Kits)-124 could regulate apoptosis and impaired autophagy process in the MPTP (show PTPN2 ELISA Kits) model of Parkinson's disease, thus reducing the loss of dopaminergic neurons

  9. Rapid activation of AMPK (show PRKAA1 ELISA Kits) was detected after exposure of cortical neuronal cultures to zinc, which was induced by LKB1 (show STK11 ELISA Kits) activation but not increased intracellular AMP (show TMPRSS5 ELISA Kits) levels or CaMKKbeta activation.

  10. Fluorizoline bind to prohibitin (show PHB ELISA Kits), inducing mitochondrial apoptotic pathway through NOXA (show PMAIP1 ELISA Kits) and BIM upregulation.

Pig (Porcine) BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) interaction partners

  1. Pseudorabies virus glycoprotein gE-mediated ERK 1 (show MAPK3 ELISA Kits)/2 phosphorylation also occurs in epithelial cells and in these cells, gE-mediated ERK 1 (show MAPK3 ELISA Kits)/2 signaling is associated with degradation of the pro-apoptotic protein Bim.

  2. BIMEL expression is regulated in porcine cumulus cells by oocyte secreted factor GDF9 (show GDF9 ELISA Kits).

  3. It was concluded that apoptotic cumulus cells, in which BIM(EL) up-regulation was involved, accelerated oocyte aging and degeneration in vitro via a paracrine action.

BIM (BCL2L11) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Alternative names and synonyms associated with BIM (BCL2L11)

  • BCL2-like 11 (bcl2l11) Elisa Kit
  • BCL2-like 11 (LOC100345483) Elisa Kit
  • BCL2-like 11 (apoptosis facilitator) (BCL2L11) Elisa Kit
  • BCL2-like 11 (apoptosis facilitator) (Bcl2l11) Elisa Kit
  • 1500006F24Rik Elisa Kit
  • BAM Elisa Kit
  • Bim Elisa Kit
  • BIMEL Elisa Kit
  • BimL Elisa Kit
  • Bod Elisa Kit

Protein level used designations for BCL2L11

BCL2-like 11 , Bcl-2 interacting mediator of cell death , bcl-2 interacting mediator of cell death , bcl-2 interacting protein Bim , bcl-2-like protein 11 , bcl-2-related ovarian death agonist , Bcl2 interacting mediator of cell death , bcl2-L-11 , bcl2-interacting mediator of cell death , Bcl-2 related apoptotic gene product BimL , bcl-2-related ovarian death protein

100190951 Danio rerio
100345483 Oryctolagus cuniculus
10018 Homo sapiens
12125 Mus musculus
64547 Rattus norvegicus
507390 Bos taurus
396632 Sus scrofa
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