Browse our CDK2 (CDK2) ELISA Kits

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Cyclin-Dependent Kinase 2 ELISA Kits (CDK2)
On www.antibodies-online.com are 43 Cyclin-Dependent Kinase 2 (CDK2) ELISA Kits from 13 different suppliers available. Additionally we are shipping CDK2 Antibodies (470) and CDK2 Proteins (38) and many more products for this protein. A total of 591 CDK2 products are currently listed.
Synonyms:
A630093N05Rik, cdk2L, CDKN2, CINP, eg1, MGC84068, p33(CDK2), wu:fa10c02, zgc:56598, zgc:77684
list all ELISA KIts Gene Name GeneID UniProt
CDK2 362817  
CDK2 1017 P24941
CDK2 12566 P97377

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Top referenced CDK2 ELISA Kits

  1. Human CDK2 ELISA Kit for Sandwich ELISA - ABIN414862 : Berenjian, Hu, Abedi-Valugerdi, Hassan, Bashir Hassan, Morein: The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells. in Leukemia & lymphoma 2014 (PubMed)

More ELISA Kits for CDK2 Interaction Partners

Xenopus laevis Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. evidence that cyclin A1 (show CCNA1 ELISA Kits)-associated activity is a mediator of apoptosis and that cyclin A1 (show CCNA1 ELISA Kits)/Cdk2 is sufficient to induce apoptosis

Human Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. Here, we introduce a transcriptional signature to specifically track CDK2 activity. It responds to genetic and chemical perturbations in the CDK (show CDK4 ELISA Kits)-RB-E2F (show E2F1 ELISA Kits) axis, correlates with mitotic rate in vitro and in vivo and reacts rapidly to changes in CDK2 activity during cell cycle progression

  2. Here, we found that centrosomal protein of 76 kDa (Cep76 (show Cep76 ELISA Kits)), previously shown to restrain centriole amplification, interacts with cyclin-dependent kinase 2 (CDK2) and is a bona fide substrate of this kinase. Cep76 (show Cep76 ELISA Kits) is preferentially phosphorylated by cyclin A (show CCNA2 ELISA Kits)/CDK2 at a single site S83, and this event is crucial to suppress centriole amplification in S phase

  3. The authors find that Spy1 (show SPDYA ELISA Kits) confers structural changes to Cdk2 that obviate the requirement of Cdk (show CDK4 ELISA Kits) activation loop phosphorylation.

  4. CDK2 serves as an important nexus linking primary beta-cell dysfunction to progressive beta-cell mass deterioration in diabetes

  5. Date show that when Wee1 (show WEE1 ELISA Kits) alone is inhibited, Chk1 (show CHEK1 ELISA Kits) suppresses CDC45 loading and thereby limits the extent of unscheduled replication initiation and subsequent S-phase DNA damage, despite very high CDK (show CDK4 ELISA Kits)-activity.

  6. Results show that cyclin E1 (show CCNE1 ELISA Kits) and CDK2 participate in STC1 (show STC1 ELISA Kits) promoting cell proliferation of prostate neoplasm cells.

  7. The data presented here suggest that the temporal separation of pro- and anti-apoptotic pathways by selective inhibition of CDK2 disrupts coherent signaling modules and may synergize with anti-proliferative drugs, averting toxic side effects from CDK1 (show CDK1 ELISA Kits) inhibition.

  8. periodic phosphorylation of Ku70 (show XRCC6 ELISA Kits) by cyclin-cyclin (show PCNA ELISA Kits) dependent kinases prevents the interaction of Ku with replication origin after initiation events in S-phase.

  9. a SUMO-deficient Rb mutant results in reduced SUMOylation and phosphorylation, weakened CDK2 binding, and attenuated E2F-1 (show E2F1 ELISA Kits) sequestration.

  10. These two states are separated by different metastable states that share hybrid structural features with both forms of the kinase. In contrast, the CDK2/ANS complex landscape is compatible with a conformational selection picture where the binding of ANS in proximity of the alphaC helix causes a population shift toward the inactive conformation

Mouse (Murine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. CDK2 serves as an important nexus linking primary beta-cell dysfunction to progressive beta-cell mass deterioration in diabetes

  2. data indicate that the essential meiotic functions of Cdk2 depend on its kinase activity, without which the generation of haploid cells is disrupted, resulting in sterility of otherwise healthy animals

  3. Testosterone is the positive regulator of hepatocyte cell cycle via cyclin E (show CCNE1 ELISA Kits)/cdk2 promoting hepatocarcinogenesis.

  4. This approach allowed us to determine the identity of cyclin E (show CCNE1 ELISA Kits) protein partners, as well as phosphorylation substrates of cyclins E (cyclin (show PCNA ELISA Kits) E1and cyclin E2 (show CCNE2 ELISA Kits))and its associated kinase, Cdk2, in different mouse organs.

  5. RingoA (show SPDYA ELISA Kits) is an important activator of Cdk2 at meiotic telomeres.

  6. Foxo3 (show FOXO3 ELISA Kits) circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2.

  7. Results identify phosphorylation of CDK2 at tyrosine 160 as a gate-keeping mechanism for hepatocyte proliferation.

  8. Sox2 (show SOX2 ELISA Kits) phosphorylation by Cdk2 promotes the establishment but not the maintenance of the pluripotent state.

  9. Our data indicate that Cdk2 and Cdk4 (show CDK4 ELISA Kits) play important overlapping roles in homeostatic and stress hematopoiesis, which need to be considered when using broad-spectrum cyclin-dependent kinase (show CDK1 ELISA Kits) inhibitors for cancer therapy.

  10. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

Zebrafish Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 ELISA Kits), wee1 (show WEE1 ELISA Kits), p21 (show CDKN1A ELISA Kits), PCNA (show PCNA ELISA Kits) and cdk2, but only weakly influences cyclin B1 (show CCNB1 ELISA Kits), cyclin B2 (show CCNB2 ELISA Kits) and cyclin E1 (show CCNE1 ELISA Kits) expression.

  2. PI3-kinase (show PIK3CA ELISA Kits) and Akt (show AKT1 ELISA Kits) participate in insulin (show INS ELISA Kits) stimulation of p34cdc2 (show CDK1 ELISA Kits) activation in zebrafish oocyte with phosphodiesterase 3 as a potential downstream target.

  3. an essential role for UHRF1 (show UHRF1 ELISA Kits) phosphorylation by cyclin-dependent kinase 2/cyclin A2 (show CCNA2 ELISA Kits) during early vertebrate development

Cow (Bovine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. cyclin D1 (show CCND1 ELISA Kits), CDK2 and CDK4 (show CDK4 ELISA Kits) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation

CDK2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Alternative names and synonyms associated with CDK2

  • MGC84068 protein (MGC84068) Elisa Kit
  • cyclin-dependent kinase 2 interacting protein (CINP) Elisa Kit
  • Cyclin-dependent kinase 2-interacting protein (cinp) Elisa Kit
  • cyclin dependent kinase 2 (Cdk2) Elisa Kit
  • cyclin-dependent kinase 2 (CDK2) Elisa Kit
  • cyclin-dependent kinase 2 (Cdk2) Elisa Kit
  • cyclin-dependent kinase 2 (cdk2) Elisa Kit
  • cyclin-dependent kinase 2 (CDK2) (Cdk2) Elisa Kit
  • cyclin-dependent kinase-2 alpha (LOC100154715) Elisa Kit
  • A630093N05Rik Elisa Kit
  • cdk2L Elisa Kit
  • CDKN2 Elisa Kit
  • CINP Elisa Kit
  • eg1 Elisa Kit
  • MGC84068 Elisa Kit
  • p33(CDK2) Elisa Kit
  • wu:fa10c02 Elisa Kit
  • zgc:56598 Elisa Kit
  • zgc:77684 Elisa Kit

Protein level used designations for CDK2

MGC84068 protein , Cyclin-dependent kinase 2-interacting protein , cyclin-dependent kinase 2 interacting protein , cyclin-dependent kinase 2-interacting protein , cell division protein kinase 2 , cyclin dependent kinase 2-alpha , cyclin-dependent kinase 2 , cdc2-related protein kinase , cell devision kinase 2 , p33 protein kinase , CDC2 homolog Eg1 protein kinase , Cell division protein kinase 2

GENE ID SPECIES
444599 Xenopus laevis
744050 Pan troglodytes
100196126 Salmo salar
362817 Rattus norvegicus
1017 Homo sapiens
12566 Mus musculus
406715 Danio rerio
399314 Xenopus laevis
100529062 Gallus gallus
606931 Canis lupus familiaris
519217 Bos taurus
100134865 Oryctolagus cuniculus
100127490 Sus scrofa
100714324 Cavia porcellus
100860751 Capra hircus
100216433 Ovis aries
101844411 Mesocricetus auratus
100689039 Cricetulus griseus
100154715 Sus scrofa
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