Browse our CDK2AP2 Proteins (CDK2AP2)

On www.antibodies-online.com are 10 Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) Proteins from 7 different suppliers available. Additionally we are shipping CDK2AP2 Antibodies (45) and CDK2AP2 Kits (3) and many more products for this protein. A total of 61 CDK2AP2 products are currently listed.
Synonyms:
5830466O21Rik, D19Ertd144e, DOC-1R, p14, p33(CDK2), zgc:92182
list all proteins Gene Name GeneID UniProt
CDK2AP2 52004 Q9CPY4
CDK2AP2 1017 P24941
Rat CDK2AP2 CDK2AP2 688405  

CDK2AP2 Proteins (CDK2AP2) by Origin

More Proteins for CDK2AP2 Interaction Partners

Mouse (Murine) Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) interaction partners

  1. Cdk2ap2 under normal conditions has a biphasic expression, suggesting regulatory roles in early-versus-late stem cell differentiation.

  2. cyclin-dependent kinase 2-associated protein 1 (CDK2AP1 (show CDK2AP1 Proteins)), an essential gene for early embryonic development, plays a role in pluripotency of ESC by engaging MBD3 (show MBD3 Proteins) to the promoter region of Wnt (show WNT2 Proteins) signaling genes

  3. Mouse DOC-1R gene can significantly inhibit cell growth and colony formation capacity.

  4. identified a mitogen-activated protein kinase (show MAPK1 Proteins) partner, DOC1R, a murine homologue of a potential human tumor suppressor gene; characterized DOC1R during mouse oocyte meiosis resumption

Human Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) interaction partners

  1. Here, we introduce a transcriptional signature to specifically track CDK2 (show CDK2 Proteins) activity. It responds to genetic and chemical perturbations in the CDK (show CDK4 Proteins)-RB-E2F (show E2F1 Proteins) axis, correlates with mitotic rate in vitro and in vivo and reacts rapidly to changes in CDK2 (show CDK2 Proteins) activity during cell cycle progression

  2. Here, we found that centrosomal protein of 76 kDa (Cep76 (show Cep76 Proteins)), previously shown to restrain centriole amplification, interacts with cyclin-dependent kinase 2 (CDK2 (show CDK2 Proteins)) and is a bona fide substrate of this kinase. Cep76 (show Cep76 Proteins) is preferentially phosphorylated by cyclin A (show CCNA2 Proteins)/CDK2 (show CDK2 Proteins) at a single site S83, and this event is crucial to suppress centriole amplification in S phase

  3. The authors find that Spy1 (show SPDYA Proteins) confers structural changes to Cdk2 (show CDK2 Proteins) that obviate the requirement of Cdk (show CDK4 Proteins) activation loop phosphorylation.

  4. CDK2 (show CDK2 Proteins) serves as an important nexus linking primary beta-cell dysfunction to progressive beta-cell mass deterioration in diabetes

  5. Date show that when Wee1 (show WEE1 Proteins) alone is inhibited, Chk1 (show CHEK1 Proteins) suppresses CDC45 (show CDC45 Proteins) loading and thereby limits the extent of unscheduled replication initiation and subsequent S-phase DNA damage, despite very high CDK (show CDK4 Proteins)-activity.

  6. Results show that cyclin E1 (show CCNE1 Proteins) and CDK2 (show CDK2 Proteins) participate in STC1 (show STC1 Proteins) promoting cell proliferation of prostate neoplasm cells.

  7. The data presented here suggest that the temporal separation of pro- and anti-apoptotic pathways by selective inhibition of CDK2 (show CDK2 Proteins) disrupts coherent signaling modules and may synergize with anti-proliferative drugs, averting toxic side effects from CDK1 (show CDK1 Proteins) inhibition.

  8. periodic phosphorylation of Ku70 (show XRCC6 Proteins) by cyclin-cyclin (show PCNA Proteins) dependent kinases prevents the interaction of Ku with replication origin after initiation events in S-phase.

  9. a SUMO-deficient Rb mutant results in reduced SUMOylation and phosphorylation, weakened CDK2 (show CDK2 Proteins) binding, and attenuated E2F-1 (show E2F1 Proteins) sequestration.

  10. These two states are separated by different metastable states that share hybrid structural features with both forms of the kinase. In contrast, the CDK2/ANS complex landscape is compatible with a conformational selection picture where the binding of ANS in proximity of the alphaC helix causes a population shift toward the inactive conformation

CDK2AP2 Protein Profile

Protein Summary

This gene encodes a protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with CDK2AP2

  • cyclin-dependent kinase 2 associated protein 2 (cdk2ap2)
  • CDK2-associated protein 2 (Cdk2ap2)
  • cyclin-dependent kinase 2 (CDK2)
  • cyclin-dependent kinase 2 associated protein 2 (CDK2AP2)
  • cyclin-dependent kinase 2 associated protein 2 (Cdk2ap2)
  • 5830466O21Rik protein
  • D19Ertd144e protein
  • DOC-1R protein
  • p14 protein
  • p33(CDK2) protein
  • zgc:92182 protein

Protein level used designations for CDK2AP2

cyclin-dependent kinase 2-associated protein 2 , DOC-1 related protein , DOC-1-related protein , cdc2-related protein kinase , cell devision kinase 2 , cell division protein kinase 2 , p33 protein kinase , CDK2-associated protein 2 , tumor suppressor deleted in oral cancer related 1 , tumor suppressor deleted in oral cancer-related 1

GENE ID SPECIES
494160 Danio rerio
52004 Mus musculus
1017 Homo sapiens
10263 Homo sapiens
688405 Rattus norvegicus
517206 Bos taurus
610458 Canis lupus familiaris
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