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DEP Domain Containing MTOR-Interacting Protein ELISA Kits (DEPTOR)
On are 3 DEP Domain Containing MTOR-Interacting Protein (DEPTOR) ELISA Kits from 2 different suppliers available. Additionally we are shipping DEPTOR Antibodies (64) and DEPTOR Proteins (4) and many more products for this protein. A total of 77 DEPTOR products are currently listed.
4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, DEP.6, Depdc6, Depdc6-001, Depdc6-002, mKIAA4200, R75183, RAPGEF4, RGD1561030
list all ELISA KIts Gene Name GeneID UniProt
DEPTOR 64798 Q8TB45
DEPTOR 97998 Q570Y9
Rat DEPTOR DEPTOR 314979  

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DEPTOR (DEPTOR) ELISA Kits by Reactivity

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Human DEP Domain Containing MTOR-Interacting Protein (DEPTOR) interaction partners

  1. Cul1 (show CUL1 ELISA Kits) promoted mTORC1 activity and cap-dependent translation by enhancing the ubiquitination and degradation of DEPTOR.

  2. Propose regulation of placental SNAT2/LAT1 ubiquitination by mTORC1 and Nedd4-2.

  3. Deptor enhances triple-negative breast cancer metastasis and chemoresistance through coupling to survivin (show BIRC5 ELISA Kits) expression

  4. Data suggest that DEPTOR has a tumor suppressive activity against pancreatic cancer cells, and its loss of expression may contribute to pancreatic tumorigenesis.

  5. Data indicate that phosphatidic acid (PA) specifically disrupts DEPTOR-mTORC1 interaction.

  6. conclude that DEPTOR-related mTOR (show FRAP1 ELISA Kits) suppression is involved in metformin's anti-cancer action in liver, and could be a novel target for anti-cancer therapy

  7. our data provide evidence for the requirement of TGFbeta (show TGFB1 ELISA Kits)-activated mTORC1 only by deptor downregulation, which dominates upon the bystander mTORC2 (show CRTC2 ELISA Kits) activity for enhanced expression of collagen I (alpha2).

  8. In Alzheimer's disease patients the mTOR (show FRAP1 ELISA Kits) pathway can be overactive, leading to a dysfunction of autophagy and a lack of amyloid beta clearance so the excess of amyloid beta will cause a further decrease in DEPTOR and an increase in mTOR (show FRAP1 ELISA Kits) expression.

  9. Receptor CXCR4 (show CXCR4 ELISA Kits) signaling promotes lysosomal and ESCRT-dependent degradation of DEPTOR, an antagonist of mTORC2 (show CRTC2 ELISA Kits), that regulates Akt (show AKT1 ELISA Kits) activation and signaling.

  10. Downregulation of DEPTOR (p=0.331) in CRC (show CALR ELISA Kits).

Mouse (Murine) DEP Domain Containing MTOR-Interacting Protein (DEPTOR) interaction partners

  1. The present study indicates that regulation of DEPTOR/mTOR (show FRAP1 ELISA Kits) signaling may be an important mechanism for glutamine (show GFPT1 ELISA Kits) in prevention against the development of colitis-associated colorectal cancer (CAC (show SLC25A20 ELISA Kits)): the chemopreventive effect of dietary glutamine (show GFPT1 ELISA Kits) on CAC (show SLC25A20 ELISA Kits) is, at least in part, associated with the induction of autophagy.

  2. DEPTOR regulates liver inflammation at least partially via mTORC1 pathway, and is down-regulated by lypopolysaccharides through p65 (show NFkBP65 ELISA Kits).

  3. p38gamma (show MAPK12 ELISA Kits) and p38delta (show MAPK1/3 ELISA Kits) control heart growth by modulating mTOR (show FRAP1 ELISA Kits) pathway through DEPTOR phosphorylation and subsequent degradation.

  4. DEPTOR plays a key role in maintaining stem cell pluripotency by limiting mTOR (show FRAP1 ELISA Kits) activity in undifferentiated embryonic stem cells

  5. DEPTOR is induced by glucocorticoids during adipogenesis and that its overexpression promotes, while its suppression blocks, adipogenesis.

  6. Data show that knockdown reduced Deptor mRNA and protein content by 90%, which increased phosphorylation of mTOR (show FRAP1 ELISA Kits) kinase substrates, 4E-BP1 (show EIF4EBP1 ELISA Kits) and S6K1 (show RPS6KB1 ELISA Kits), and concomitantly increased protein synthesis.

DEPTOR Antigen Profile

Antigen Summary

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes (By similarity).

Alternative names and synonyms associated with DEPTOR

  • DEP domain containing MTOR-interacting protein (DEPTOR) Elisa Kit
  • DEP domain containing MTOR-interacting protein (Deptor) Elisa Kit
  • 4731402B04Rik Elisa Kit
  • 9130412E02Rik Elisa Kit
  • D15Ertd336e Elisa Kit
  • D15Ertd597e Elisa Kit
  • DEP.6 Elisa Kit
  • Depdc6 Elisa Kit
  • Depdc6-001 Elisa Kit
  • Depdc6-002 Elisa Kit
  • mKIAA4200 Elisa Kit
  • R75183 Elisa Kit
  • RAPGEF4 Elisa Kit
  • RGD1561030 Elisa Kit

Protein level used designations for DEPTOR

DEP domain containing MTOR-interacting protein , DEP domain containing 6 , DEP domain containing mTOR interacting protein , DEP domain-containing mTOR-interacting protein , DEP domain-containing protein 6 , Rap guanine nucleotide exchange factor (GEF) 4

100543973 Meleagris gallopavo
100601105 Nomascus leucogenys
64798 Homo sapiens
97998 Mus musculus
100057185 Equus caballus
314979 Rattus norvegicus
419242 Gallus gallus
482028 Canis lupus familiaris
100157658 Sus scrofa
617606 Bos taurus
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