Browse our FOXO1 Proteins (FOXO1)

On www.antibodies-online.com are 9 Forkhead Box O1 (FOXO1) Proteins from 5 different suppliers available. Additionally we are shipping FOXO1 Antibodies (433) and FOXO1 Kits (57) and many more products for this protein. A total of 520 FOXO1 products are currently listed.
Synonyms:
Afxh, AI876417, FKH1, Fkhr, Fkhr1, foxo1, FoxO1A, FoxO1a.1, xFoxO1, zgc:153388
list all proteins Gene Name GeneID UniProt
FOXO1 2308 Q12778
FOXO1 56458 Q9R1E0
Rat FOXO1 FOXO1 84482  

FOXO1 Proteins (FOXO1) by Origin

More Proteins for FOXO1 Interaction Partners

Cow (Bovine) Forkhead Box O1 (FOXO1) interaction partners

  1. MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.

  2. downregulation of SIRT1 (show SIRT1 Proteins) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age

  3. FOXO (show FOXO3 Proteins) is a key regulator of ROS (show ROS1 Proteins)-induced apoptosis in mammalian cells.

  4. Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (show NCAM1 Proteins)-1 mRNA.

  5. The results demonstrate pathways through which two different mediators, TNF-alpha (show TNF Proteins) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.

Human Forkhead Box O1 (FOXO1) interaction partners

  1. The FOXO1 serves a pivotal role in LEC migration toward exogenous ATP via direct transcriptional regulation of P2Y1 receptor (show P2RY1 Proteins).

  2. miR (show MLXIP Proteins)-615-3p negatively regulates the osteogenic differentiation of hLF (show EPAS1 Proteins) cells through post-transcriptionally suppressing osteogenic regulators GDF5 (show GDF5 Proteins) and FOXO1.

  3. our findings identify the TXN (show TXN Proteins)-FOXO1-p300 (show EP300 Proteins) circuit as the sensor and effector of oxidative stress in DLBCL cells

  4. Study confirmed that the crosstalk of esophageal squamous cell carcinoma (ESCC) cells and cancer-associated fibroblasts promoted the expression and activation of FOXO1, which then caused TGFb1 (show TGFB1 Proteins) expression in an autocrine/paracrine signaling loop resulting in ESCC chemoresistance.

  5. PAX3 (show PAX3 Proteins)-FOXO1 collaborates with MYCN (show MYCN Proteins) during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

  6. Ik6, the upstream factor of Akt (show AKT1 Proteins)-FoxO1 pathway, can protect acute lymphoblastic leukemia cells against daunorubicin-induced apoptosis

  7. elevated serum and cellular levels of mTOR (show FRAP1 Proteins) in the IGT group and FOXO-1 in IFG (show IFNG Proteins) and IGT groups may be triggered by increased glucose concentration. Indeed, mTOR (show FRAP1 Proteins)-mediated variations in cellular level from female patients and FOXO-1-mediated variations of male patients indicated that these factors might play a critical role in glucose intolerance.

  8. This study provides new insights on the action of insulin (show INS Proteins) on the endometrium via regulation of FOXO1.

  9. the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system

  10. elevated FOXO1 contributes to BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) kinase-independent resistance experienced by relapsed CML (show BCR Proteins) patients lacking BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) kinase domain mutations

Pig (Porcine) Forkhead Box O1 (FOXO1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing the activation of TLR4 and/or NOD2 signaling pathways.

  2. let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (show MAP3K1 Proteins) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.

  3. inhibition of FoxO1 expression level caused by miR (show MYLIP Proteins)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (show MYLIP Proteins)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1

  4. Results show that FoxO1 likely regulates MyHC I (show MYH7 Proteins) negatively and MyHC IIx and MyHC IIb (show MYH4 Proteins) positively and may play a pivotal role in the determination of muscle fiber type.

  5. Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (show TNFSF10 Proteins) and Fas ligand FasL (show FASL Proteins) expression during follicular atresia.

  6. Data show that IL-4 (show IL4 Proteins) induces upregulation of the junction protein claudin-5 (show CLDN5 Proteins) in endothelial cells (ECs) through activation of Jak (show JAK3 Proteins)/STAT6 (show STAT6 Proteins) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.

  7. FoxO1 and C/EBPb (show CEBPB Proteins) regulate preadipocyte adipogenesis possibly through C/EBPb (show CEBPB Proteins)-> FoxO1-> C/EBPb (show CEBPB Proteins) feedback regulatory loop and FoxO1-C/EBPb (show CEBPB Proteins) protein complex.

  8. FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.

  9. concluded that PI 3 (show PI3 Proteins)-kinase and Akt (show AKT1 Proteins) are activated after renal ischemia/reperfusion and that Akt (show AKT1 Proteins) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (show FOXO3 Proteins), which may affect epithelial cell fate in acute renal failure.

  10. FoxO1a can regulate p27kip nuclear localization

Mouse (Murine) Forkhead Box O1 (FOXO1) interaction partners

  1. These results suggest that the LKB1 (show STK11 Proteins)-AMPK (show PRKAA1 Proteins)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.

  2. These data strongly suggest that intestinal apoC-III (show APOC3 Proteins) is not a FoxO1 target and support the idea that apoC-III (show APOC3 Proteins) is not regulated coordinately with hepatic apoC-III (show APOC3 Proteins), and establishes another key aspect of apoC-III (show APOC3 Proteins) that is unique in the intestine from the liver.

  3. this study shows that miR (show MLXIP Proteins)-183C drives Th17 pathogenicity in experimental autoimmune encephalomyelitis via inhibition of Foxo1

  4. The findings of this study suggest that Foxo (show FOXO3 Proteins)-regulated pathways are downstream of Isl1 (show ISL1 Proteins) in the survival and/or differentiation of direct pathway striatal projection neurons.

  5. Endothelial FoxO (show FOXO3 Proteins) proteins promote insulin (show INS Proteins) resistance in HF diet, which may in part result from FoxO (show FOXO3 Proteins) proteins establishing an antiangiogenic and proinflammatory microenvironment within skeletal muscle. These findings provide mechanistic insight into the development of microvascular dysfunction in the progression of type 2 diabetes.-

  6. ablation of Foxo1 after Germinal center (GC) development led to the loss of the dark zone GC B (show NPR2 Proteins) cells and disruption of the GC architecture.

  7. Suppression of Sirt1 (show SIRT1 Proteins) or Foxo-1 expression significantly impaired exendin-4-induced adiponectin (show ADIPOQ Proteins) expression. Consistently, exendin-4 up-regulated Sirt1 (show SIRT1 Proteins) and Foxo-1 expression in vivo. Our work is the first study demonstrating the role of Sirt1 (show SIRT1 Proteins)/Foxo-1 in regulating the regulatory function of a GLP-1 receptor (show GLP1R Proteins) agonist in adiponectin (show ADIPOQ Proteins) expression both in vitro and in vivo.

  8. This study shows that TNF-alpha (show TNF Proteins), by a Foxo1 dependent pathway, increases the transcription of ANGPTL4 (show ANGPTL4 Proteins) which is secreted by the cells and causes inactivation of LPL (show LPL Proteins).

  9. JNK (show MAPK8 Proteins)/FoxO1 is involved in the regulation of oxidative stress-induced (show SQSTM1 Proteins) cell apoptosis in MGCs

  10. Increased Forkhead box protein 1 (FoxO1) acetylation and nuclear retention was followed by progressive FoxO1 loss in beta cells that marked the onset of diabetes.

Xenopus laevis Forkhead Box O1 (FOXO1) interaction partners

  1. FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (show SOD1 Proteins) and catalase (show CAT Proteins) mRNA and protein levels in this organ.

Zebrafish Forkhead Box O1 (FOXO1) interaction partners

  1. These results indicate that miR (show MYLIP Proteins)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.

  2. gas6 (show GAS6 Proteins) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (show AKT1 Proteins)-dependent inactivation of FOXO1a.

FOXO1 Protein Profile

Protein Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Alternative names and synonyms associated with FOXO1

  • forkhead box O1 (FOXO1)
  • forkhead box O1 (foxo1)
  • forkhead box O1 (Foxo1)
  • forkhead box O1 a (foxo1a)
  • Afxh protein
  • AI876417 protein
  • FKH1 protein
  • Fkhr protein
  • Fkhr1 protein
  • foxo1 protein
  • FoxO1A protein
  • FoxO1a.1 protein
  • xFoxO1 protein
  • zgc:153388 protein

Protein level used designations for Forkhead Box O1 Proteins (FOXO1)

forkhead box O1 , forkhead box O1A , forkhead box O1A (rhabdomyosarcoma) , forkhead box protein O1 , forkhead box protein O1-like , forkhead box protein O1A , forkhead, Drosophila, homolog of, in rhabdomyosarcoma , Forkhead box protein O1A , Forkhead in rhabdomyosarcoma , forkhead/winged helix transcription factor FOXO1a , forkhead in rhabdomyosarcoma , forkhead box O1a , forkhead protein 1 , xFoxO1 , forkhead box protein O1-A , fox family transcription factor FoxO1a.1 , foxhead box protein O1-A

GENE ID SPECIES
100050481 Equus caballus
282234 Bos taurus
467352 Pan troglodytes
493378 Xenopus (Silurana) tropicalis
700030 Macaca mulatta
100460676 Pongo abelii
100594615 Nomascus leucogenys
2308 Homo sapiens
374231 Gallus gallus
397077 Sus scrofa
506618 Bos taurus
56458 Mus musculus
84482 Rattus norvegicus
444991 Xenopus laevis
477295 Canis lupus familiaris
101107877 Ovis aries
768121 Danio rerio
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