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Browse our GRIA2 Proteins (GRIA2)

Full name:
Glutamate Receptor, Ionotropic, AMPA 2 Proteins (GRIA2)
On www.antibodies-online.com are 8 Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) Proteins from 2 different suppliers available. Additionally we are shipping GRIA2 Antibodies (150) and GRIA2 Kits (40) and many more products for this protein. A total of 207 GRIA2 products are currently listed.
Synonyms:
GluA2, Glur-2, GluR-B, GluR-K2, Glur2, GLURB, HBGR2
list all proteins Gene Name GeneID UniProt
GRIA2 2891 P42262
Rat GRIA2 GRIA2 29627 P19491
GRIA2 14800 P23819

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GRIA2 Proteins (GRIA2) by Origin

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Human Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) interaction partners

  1. A transient positive feedback mechanism between AMPAR and stargazin has implications for information processing in the brain, because it should allow activity-dependent facilitation of excitatory synaptic transmission through a postsynaptic mechanism.

  2. The GluR2 subunit of the AMPA (show GRIA3 Proteins) receptor is involved in cell migration and calcium signaling.

  3. RAB39B (show RAB39B Proteins) selectively regulates GluA2 trafficking to determine synaptic AMPAR composition

  4. GRIA2*CCC polymorphism is genetic risk marker for paranoid schizophrenia in Russians.Low risk genetic markers of paranoid schizophrenia were revealed: in Tatars-GRIA2*T/T (rs43025506) of GRIA2 gene and GRIA2*CCT in Russians.

  5. GRIA2 is a useful marker for distinguishing solitary fibrous tumour from most mimics

  6. a link between neurodegenerative processes and deficient RNA editing of the GluA2 Q/R site.

  7. the levels were comparable for complexes containing GluR2, GluR3 (show GRIA3 Proteins) and GluR4 (show GRIA4 Proteins) as well as 5-HT1A (show HTR1A Proteins). Moreover, the levels of complexes containing muscarinic AChR M1, NR1 (show GRIN1 Proteins) and GluR1 (show GRIA1 Proteins) were significantly increased in male patients with AD.

  8. Statistical analysis showed no association between migraine and the GRIA2 and GRIA4 (show GRIA4 Proteins) polymorphisms investigated.

  9. The N-terminal domain modulates alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA (show GRIA3 Proteins)) receptor desensitization.

  10. analysis of changes in receptor kinetics with the R628E charge-inverting mutation in the "linker" region of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA (show GRIA3 Proteins)) receptor

Mouse (Murine) Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) interaction partners

  1. found the protein levels of AMPA (show GRIA3 Proteins) receptor subunits (GluR1 (show GRIA1 Proteins) and GluR2) are upregulated in the amygdala and the 5-HT3 receptor (show HTR3A Proteins) is downregulated in hypothalamic regions of Socially Isolated mice.

  2. These results provide direct evidence for cortical AMPA (show GRIA3 Proteins) receptors to contribute to zymosan-induced visceral and spontaneous pain.

  3. Animals trained in the trace fear conditioning protocol had GluA2 RNA editing levels were nearly 100% in amygdala and hippocampus.

  4. These results provide evidence for VPS35 (show vps35 Proteins)'s function in promoting spine maturation, which is likely through increasing AMPA (show GRIA3 Proteins) receptor targeting to the postsynaptic membrane.

  5. Bacopa monnieri extract (CDRI-08) upregulates the expression of the GluR2 subunit in the CA3 (show CA3 Proteins) area of the hippocampus.

  6. subcellular redistribution of GRIP1 (show NCOA2 Proteins) and a change in the binding of GRIP1 (show NCOA2 Proteins) to GluA2 during synaptic scaling, was observed.

  7. Data indicate that the AMPA (show GRIA3 Proteins) receptor subunits abundance is hippocampus, GluA2 > GluA1 (show GRIA1 Proteins) > GluA3 (show GRIA3 Proteins) >> GluA4 (show GRIA4 Proteins); cortex, GluA2 > GluA3 (show GRIA3 Proteins) >/= GluA1 (show GRIA1 Proteins) >> GluA4 (show GRIA4 Proteins); and cerebellum, GluA2 > GluA3 (show GRIA3 Proteins) >/= GluA1 (show GRIA1 Proteins) > GluA4 (show GRIA4 Proteins).

  8. Loss of long-term potentiation was linked to reduced N-methyl-D-aspartate (NMDA) to alpha-amino-3-hydroxy- 5-methyl-4-isoxazolepropionic acid (AMPA (show GRIA3 Proteins)) current ratio.

  9. Removal of FXR1P (show FXR1 Proteins) from the forebrain of postnatal mice selectively enhances long-term storage of spatial memories, hippocampal late-phase long-term potentiation (L-LTP (show SCP2 Proteins)), and de novo GluA2 synthesis.

  10. The data of this study support a model in which GluA2 is translated in the cell body and subsequently transported to neuronal dendrites and synapses, and synaptic GluA2 concentrations are modified primarily by regulated protein trafficking.

GRIA2 Protein Profile

Protein Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG\; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

Alternative names and synonyms associated with GRIA2

  • glutamate receptor, ionotropic, AMPA 2 (GRIA2)
  • glutamate receptor, ionotropic, AMPA 2 (Gria2)
  • glutamate receptor, ionotropic, AMPA 2 (gria2)
  • glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2)
  • GluA2 protein
  • Glur-2 protein
  • GluR-B protein
  • GluR-K2 protein
  • Glur2 protein
  • GLURB protein
  • HBGR2 protein

Protein level used designations for GRIA2

AMPA-selective glutamate receptor 2 , Glutamate receptor 2 , gluR-2 , gluR-B , gluR-K2 , glutamate receptor ionotropic, AMPA 2 , glutamate receptor 2 , glutamate receptor B , AMPA glutamate receptor 2 , AMPA receptor GluR2/B , AMPA selective glutamate receptor , glutamate receptor AMPA 2

GENE ID SPECIES
100174733 Pongo abelii
100069331 Equus caballus
2891 Homo sapiens
29627 Rattus norvegicus
100294514 Xenopus laevis
414894 Gallus gallus
614283 Bos taurus
100622950 Sus scrofa
482667 Canis lupus familiaris
14800 Mus musculus
100379153 Cavia porcellus
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