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Browse our anti-PIP5K1C (PIP5K1C) Antibodies

Full name:
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma Antibodies (PIP5K1C)
On www.antibodies-online.com are 41 Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antibodies from 13 different suppliers available. Additionally we are shipping PIP5K1C Proteins (7) and many more products for this protein. A total of 58 PIP5K1C products are currently listed.
Synonyms:
AI115456, AI835305, LCCS3, MGC130766, PIP5K-GAMMA, pip5k1a, PIP5K1C, PIP5Kgamma, Pip5kIgamma, PIPKIg_v4, si:dkey-29i9.1, zgc:110576
list all antibodies Gene Name GeneID UniProt
PIP5K1C 18717 O70161
PIP5K1C 23396 O60331
PIP5K1C 314641 Q5I6B8

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Most Popular Reactivities for anti-PIP5K1C (PIP5K1C) Antibodies

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anti-Mouse (Murine) PIP5K1C Antibodies:

anti-Human PIP5K1C Antibodies:

anti-Rat (Rattus) PIP5K1C Antibodies:

All available anti-PIP5K1C Antibodies

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Top referenced anti-PIP5K1C Antibodies

  1. Human Polyclonal PIP5K1C Primary Antibody for EIA, IHC (p) - ABIN360480 : Ling, Doughman, Firestone, Bunce, Anderson: Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. in Nature 2002 (PubMed)
    Show all 3 references for ABIN360480

  2. Mouse (Murine) Monoclonal PIP5K1C Primary Antibody for IF, WB - ABIN968393 : Ishihara, Shibasaki, Kizuki, Wada, Yazaki, Asano, Oka: Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for ABIN968393

  3. Human Polyclonal PIP5K1C Primary Antibody for EIA, IHC (p) - ABIN360481 : Di Paolo, Pellegrini, Letinic, Cestra, Zoncu, Voronov, Chang, Guo, Wenk, De Camilli: Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. in Nature 2002 (PubMed)
    Show all 3 references for ABIN360481

  4. Human Polyclonal PIP5K1C Primary Antibody for ELISA, WB - ABIN1535167 : Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: The DNA sequence and biology of human chromosome 19. ... in Nature 2004 (PubMed)

More Antibodies against PIP5K1C Interaction Partners

Zebrafish Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) interaction partners

  1. Pip5k1a activity is regulated by dimerization and binding with the DIX domain of dishevelled (show DVL2 Antibodies).

Mouse (Murine) Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) interaction partners

  1. PIPKIgamma and INPP5E (show INPP5E Antibodies) localize to the centrosome and coordinate the initiation of ciliogenesis.

  2. PIPKIgamma, downstream of EGF (show EGF Antibodies) and/or HGF receptor, participates in breast cancer progression

  3. Shp1 binds and controls PIPKIgamma activity and, thereby, modulates phosphatidylinositol (4,5)-bisphosphate levels and adhesion.

  4. The results of this study suggest that PIP5KIgamma, especially PIP5KIgamma_i2, is localized at the periactive zone, a functionally suitable compartment for the endocytosis of synaptic vesicles in photoreceptor ribbon synapses.

  5. The lipid kinase PIP5K1C regulates pain signaling and sensitization in mice.

  6. The findings suggest an essential role of PIP5KIgamma, particularly PIP5KIgamma_i2, in neuronal migration, possibly through recruitment of adhesion components to the plasma membrane.

  7. Although PIP5KIgamma is essential for normal platelet function, individual isoforms of PIP5KIgamma fulfill unique roles for the integrin-dependent integrity of the membrane cytoskeleton and for the stabilization of platelet adhesion.

  8. NMDA receptor activation controls AMPA AMPA AMPA (show GRIA3 Antibodies) receptor endocytosis during hippocampal LTD by regulating PIP5Kgamma661 activity at postsynapses.

  9. PIP5KIgamma-mediated generation of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) at sites of N-cadherin (show CDH2 Antibodies) contacts regulates intercellular adhesion strength, an effect due in part to PI(4,5)P2-mediated regulation of gelsolin (show GSN Antibodies).

  10. PIP5K1C-90 polarization was required for polarized RhoA activation at uropods and provided an initial directional cue for neutrophil polarization on the endothelium.

Human Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) interaction partners

  1. PIPKIgamma and INPP5E localize to the centrosome and coordinate the initiation of ciliogenesis.

  2. results suggested that Akt (show AKT1 Antibodies)-mediated PIP5Kgamma90 S555 phosphorylation is a novel regulatory point for talin binding to control PIP2 level at the FAs (show FAS Antibodies), thereby modulating FA dynamics and cell motility.

  3. Loss of PIPKIgamma or its focal adhesion-targeting variant, PIPKIgammai2, impaired PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) activation upon stimulation with growth factors or extracellular matrix proteins in different tumor cells.

  4. PIPKIgamma binds to the cryptic polo (show PLK1 Antibodies)-box domain of PLK4 (show PLK4 Antibodies) and reduces the kinase activity of PLK4 (show PLK4 Antibodies).

  5. This study uncovers a novel mechanism where a phosphoinositide-synthesizing enzyme, PIPKIgammai2, functions with the proto-oncogene (show RAB1A Antibodies) Src (show SRC Antibodies), to regulate oncogenic signaling

  6. PIPKIgamma and phosphatidyl inositol phosphate pools at nascent E-cadherin (show CDH1 Antibodies) contacts cue Exo70 (show EXOC7 Antibodies) targeting and orient the tethering of exocyst-associated E-cadherin (show CDH1 Antibodies)

  7. PIPKIgamma positively regulates focal adhesion dynamics and cancer invasion, most probably through PIP (show PIP Antibodies)-mediated vinculin (show VCL Antibodies) activation.

  8. EZH2 (show EZH2 Antibodies) regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling.

  9. A novel mechanism in which PIPKIgamma expression and catalytic activity enhance beta-catenin (show CTNNB1 Antibodies) nuclear translocation and expression of its target genes to promote tumorigenic phenotypes.

  10. SIRT1 (show SIRT1 Antibodies) deacetylated two specific lysine residues (K265/K268) in PIP5Kgamma and enhanced PIP5Kgamma enzyme activity.

PIP5K1C Antigen Profile

Antigen Summary

This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with PIP5K1C

  • phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (pip5k1c) antibody
  • phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C) antibody
  • phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a (pip5k1aa) antibody
  • phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma (Pip5k1c) antibody
  • phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (Pip5k1c) antibody
  • AI115456 antibody
  • AI835305 antibody
  • LCCS3 antibody
  • MGC130766 antibody
  • PIP5K-GAMMA antibody
  • pip5k1a antibody
  • PIP5K1C antibody
  • PIP5Kgamma antibody
  • Pip5kIgamma antibody
  • PIPKIg_v4 antibody
  • si:dkey-29i9.1 antibody
  • zgc:110576 antibody

Protein level used designations for PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma , phosphatidylinositol-4-phosphate 5-kinase type-1 gamma , PIP5K1-gamma , phosphatidylinositol 4-phosphate 5-kinase type I gamma , phosphatidylinositol 4-phosphate 5-kinase type-1 gamma , phosphatidylinositol-4-phosphate 5-kinase type I gamma , ptdIns(4)P-5-kinase 1 gamma , Human homolog of mouse phosphatidylinositol-4-phosphate 5-kinase I-gamma , diphosphoinositide kinase , type I PIP kinase , PIP5KIgamma , phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma , ptdIns(4)P-5-kinase gamma , ptdInsPKIgamma

GENE ID SPECIES
398687 Xenopus laevis
420072 Gallus gallus
455590 Pan troglodytes
485054 Canis lupus familiaris
508819 Bos taurus
553629 Danio rerio
555708 Danio rerio
100145583 Xenopus (Silurana) tropicalis
18717 Mus musculus
23396 Homo sapiens
314641 Rattus norvegicus
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