Browse our anti-RPS6KB1 (RPS6KB1) Antibodies

Full name:
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 Antibodies (RPS6KB1)
On www.antibodies-online.com are 674 Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies from 36 different suppliers available. Additionally we are shipping RPS6KB1 Kits (33) and RPS6KB1 Proteins (14) and many more products for this protein. A total of 768 RPS6KB1 products are currently listed.
Synonyms:
70kDa, 2610318I15Rik, 4732464A07Rik, AA959758, AI256796, AI314060, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, p70/85s6k, p70s6k, PS6K, S6K, S6K-beta-1, S6K1, STK14A
list all antibodies Gene Name GeneID UniProt
RPS6KB1 6198 P23443
RPS6KB1 72508 Q8BSK8
RPS6KB1 83840 P67999

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Top referenced anti-RPS6KB1 Antibodies

  1. Cow (Bovine) Polyclonal RPS6KB1 Primary Antibody for ICC, IF - ABIN361700 : Gout, Minami, Hara, Tsujishita, Filonenko, Waterfield, Yonezawa: Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. in The Journal of biological chemistry 1998 (PubMed)
    Show all 6 references for 361700

  2. Human Polyclonal RPS6KB1 Primary Antibody for EIA - ABIN358318 : Adem, Soderberg, Hafner, Reynolds, Slezak, Sinclair, Sellers, Schaid, Couch, Hartmann, Jenkins: ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers. in Genes, chromosomes & cancer 2004 (PubMed)
    Show all 5 references for 358318

  3. Human Polyclonal RPS6KB1 Primary Antibody for IF, IHC - ABIN1531360 : Chan, Wang, Fang, Chen: Fibrous papule of the face, similar to tuberous sclerosis complex-associated angiofibroma, shows activation of the mammalian target of rapamycin pathway: evidence for a novel therapeutic strategy? in PLoS ONE 2014 (PubMed)
    Show all 2 references for 1531360

  4. Human Polyclonal RPS6KB1 Primary Antibody for IHC, ELISA - ABIN184828 : Grove, Banerjee, Balasubramanyam, Coffer, Price, Avruch, Woodgett: Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. in Molecular and cellular biology 1991 (PubMed)

  5. Human Polyclonal RPS6KB1 Primary Antibody for IHC, ELISA - ABIN1533663 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  6. Cow (Bovine) Polyclonal RPS6KB1 Primary Antibody for WB - ABIN2786770 : Ma, Yoon, Richardson, Jülich, Blenis: SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. in Cell 2008 (PubMed)

More Antibodies against RPS6KB1 Interaction Partners

Human Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. Data show that acquired immunodeficiency syndrome (AIDS) related diffuse large B-cell lymphoma (AR-DLBCL) frequently contain phosphorylated 70 ribosomal S6 protein-kinase (show CDK7 Antibodies) (p70S6K), a main downstream effector of the mTOR (show FRAP1 Antibodies) serine-threonine kinases (mTOR (show FRAP1 Antibodies)) pathway, and the presence of p70S6K is positively correlated with phosphorylated phosphatase and tensin homolog (show PTEN Antibodies) (pPTEN).

  2. S6K1 is a promising tumor-specific target for the enhancement of NSCLC radiosensitivity and its effects may be mediated by increased expression of PDCD4 (show PDCD4 Antibodies).

  3. Spheroids showed relative lower activities in the AKT (show AKT1 Antibodies), mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) and S6K (also known as RPS6KB1) signaling pathway compared to cells cultured in two dimensions.

  4. S6K1 phosphorylation of H2B mediates EZH2 (show EZH2 Antibodies) trimethylation of H3 early in adipogenesis, contributing to the promotion of obesity.

  5. Findings indicate that similar to overall cell size growth, Golgi growth is modulated by the "cell growth checkpoint" at late G1 phase through the activities of S6 kinase 1 (S6K1).

  6. the results identify the JNK (show MAPK8 Antibodies)/S6K1 axis as a key molecular mechanism whereby a high fat/sucrose diet impairs insulin (show INS Antibodies) action in retina.

  7. these findings suggest that activation of S6K1 in an adjuvant trastuzumab setting may represent a reliable early tumor marker predicting patient response to trastuzumab, allowing clinicians to further stratify patients for personalized and effective therapy.

  8. Data indicate YAP1 (show YAP1 Antibodies) as a candidate marker to predict cell lines that were most sensitive to MSC2363318A, suggesting clinical development of a dual AKT (show AKT1 Antibodies)/P70S6K inhibitor.

  9. RPS6KB1 single nucleotide polymorphism association with colorectal cancer patients survival

  10. These data suggest that S6K1-mediated PIPKIgamma90 phosphorylation regulates cell migration and invasion by controlling PIPKIgamma90 degradation.

Cow (Bovine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 Antibodies), mTOR (show FRAP1 Antibodies), p70S6K, and ERK1/2 (show MAPK1/3 Antibodies).

  2. Lys (show LYZ Antibodies), His, and Thr (show TRH Antibodies) inhibited S6K1 phosphorylation in bovine mammary cells

Pig (Porcine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. This study found that, early in rotavirus enteritis, arginine has no impact on diarrhea but augments intestinal protein synthesis in part by p70(S6k) stimulation.

  2. There was no correlation of infarct size with expression or phosphorylation of p70S6K or GSK3beta (show GSK3b Antibodies) in ischemic postconditioning.

Mouse (Murine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. We provide mechanistic evidence that S6K1's negative feedback to PI3K signaling is involved in axon growth inhibition, and show that phosphorylation of S6K1 is a more appropriate regeneration indicator than is S6 phosphorylation.

  2. S6K1 phosphorylation of H2B mediates EZH2 (show EZH2 Antibodies) trimethylation of H3 early in adipogenesis, contributing to the promotion of obesity.

  3. the p70S6K isoforms have unique and redundant functions in mediating fibrogenic processes, including proliferation, migration.

  4. Rcan2 (show RCAN2 Antibodies) and Rps6kb1 mutations both affect growth and body weight of mice, though likely through different mechanisms

  5. Findings indicate that similar to overall cell size growth, Golgi growth is modulated by the "cell growth checkpoint" at late G1 phase through the activities of S6 kinase 1 (S6K1).

  6. the results identify the JNK (show MAPK8 Antibodies)/S6K1 axis as a key molecular mechanism whereby a high fat/sucrose diet impairs insulin (show INS Antibodies) action in retina.

  7. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1)-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 Antibodies)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 Antibodies)).

  8. Our study suggests that Ab25-35 induces autophagy and the PI3K/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies)/p70S6K pathway is involved in the process, which improves our understanding of the pathogenesis of Alzheimer's disease and provides an additional model for AD research

  9. Reducing S6K activity prevents accelerated axon growth induced by hyperactive mTOR (show FRAP1 Antibodies) in vivo.

  10. targeting the S6K pathway selectively modifies the progression of pulmonary fibrosis in the subpleural compartment of the lung

RPS6KB1 Antigen Profile

Antigen Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Alternative names and synonyms associated with RPS6KB1

  • ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) antibody
  • ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1) antibody
  • 70kDa antibody
  • 2610318I15Rik antibody
  • 4732464A07Rik antibody
  • AA959758 antibody
  • AI256796 antibody
  • AI314060 antibody
  • p70 S6KA antibody
  • p70(S6K)-alpha antibody
  • p70-alpha antibody
  • p70-S6K antibody
  • p70/85s6k antibody
  • p70s6k antibody
  • PS6K antibody
  • S6K antibody
  • S6K-beta-1 antibody
  • S6K1 antibody
  • STK14A antibody

Protein level used designations for RPS6KB1

p70 S6 kinase, alpha , ribosomal protein S6 kinase I , ribosomal protein S6 kinase beta-1 , serine/threonine kinase 14 alpha , serine/threonine-protein kinase 14A , 70 kDa ribosomal protein S6 kinase 1 , P70S6K1 , S6K , S6K-beta-1 , p70 S6 kinase alpha , p70(S6K)-alpha , p70-S6K 1 , p70S6K , ribosomal protein S6 kinase polypeptide 1 , G3 serine/threonine kinase , P70S6K , S6K1 , p70 S6K-alpha , p70 S6KA , p70 ribosomal S6 kinase alpha , ribosomal protein S6 kinase, 70kD, polypeptide 1 , S6 kinase , ribosomal protein S6 kinase, 70kDa, polypeptide 1

GENE ID SPECIES
100057481 Equus caballus
6198 Homo sapiens
404181 Bos taurus
417637 Gallus gallus
480580 Canis lupus familiaris
100127158 Sus scrofa
100009260 Oryctolagus cuniculus
72508 Mus musculus
83840 Rattus norvegicus
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