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Browse our anti-RPS6KB1 (RPS6KB1) Antibodies

Full name:
anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 Antibodies (RPS6KB1)
On are 691 Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies from 36 different suppliers available. Additionally we are shipping RPS6KB1 Kits (33) and RPS6KB1 Proteins (13) and many more products for this protein. A total of 784 RPS6KB1 products are currently listed.
70kDa, 2610318I15Rik, 4732464A07Rik, AA959758, AI256796, AI314060, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, p70/85s6k, p70s6k, PS6K, S6K, S6K-beta-1, S6K1, STK14A
list all antibodies Gene Name GeneID UniProt
RPS6KB1 6198 P23443
RPS6KB1 72508 Q8BSK8
RPS6KB1 83840 P67999

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Top referenced anti-RPS6KB1 Antibodies

  1. Human Polyclonal RPS6KB1 Primary Antibody for IHC (p), WB - ABIN4620526 : Adem, Soderberg, Hafner, Reynolds, Slezak, Sinclair, Sellers, Schaid, Couch, Hartmann, Jenkins: ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers. in Genes, chromosomes & cancer 2004 (PubMed)
    Show all 5 references for ABIN4620526

  2. Human Polyclonal RPS6KB1 Primary Antibody for EIA, WB - ABIN4620525 : Suzuki, Yamashita, Shirota, Sakakibara, Chiba, Mizushima-Sugano, Nakai, Sugano: Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. in Genome research 2004 (PubMed)
    Show all 5 references for ABIN4620525

  3. Cow (Bovine) Polyclonal RPS6KB1 Primary Antibody for EIA, IP - ABIN264871 : Gout, Minami, Hara, Tsujishita, Filonenko, Waterfield, Yonezawa: Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for ABIN264871

  4. Human Polyclonal RPS6KB1 Primary Antibody for IF, IHC - ABIN1531360 : Chan, Wang, Fang, Chen: Fibrous papule of the face, similar to tuberous sclerosis complex-associated angiofibroma, shows activation of the mammalian target of rapamycin pathway: evidence for a novel therapeutic strategy? in PLoS ONE 2014 (PubMed)
    Show all 2 references for ABIN1531360

  5. Human Polyclonal RPS6KB1 Primary Antibody for IHC, ELISA - ABIN1533663 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  6. Cow (Bovine) Polyclonal RPS6KB1 Primary Antibody for EIA, IHC (p) - ABIN374267 : Grove, Banerjee, Balasubramanyam, Coffer, Price, Avruch, Woodgett: Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. in Molecular and cellular biology 1991 (PubMed)

  7. Human Polyclonal RPS6KB1 Primary Antibody for WB - ABIN2786769 : Ma, Yoon, Richardson, Jülich, Blenis: SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. in Cell 2008 (PubMed)

More Antibodies against RPS6KB1 Interaction Partners

Human Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. These results indicated that p-p70S6K may participate in the invasion and metastasis in the development of ESCC and downregulation of the expression of p-p70S6K could improve the sensitivity of cells to rapamycin in ESCC.

  2. RPS6KB1 SNPs associated with susceptibility to multiple sclerosis in Iranian population.

  3. We found that S6K1 Iso-2 overexpression in cancer cells promoted cell growth and inhibited apoptosis, denotes its important role on NSCLC survival.

  4. S6K phosphorylation via the PI3K-PD1 pathway is involved in tau pathology in neurofibrillary tangles and abnormal neurites as well as actin pathology in Hirano bodies.

  5. Data suggest the role of the phospholipase C epsilon (show PLCL1 Antibodies)-Protein kinase D (show PRKD1 Antibodies)-PEA15 (show PEA15 Antibodies) protein-ribosomal S6 kinase-IkappaB-NF-kappa B (show NFKB1 Antibodies) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.

  6. These results indicate that the inhibitory effect of rapamycin may be due mainly to increased p14 (show S100A9 Antibodies), p15 (show CDKN2B Antibodies), and p57 (show CDKN1C Antibodies) expression via promoter demethylation and decreased mTOR (show FRAP1 Antibodies) and p70S6K expression in ALL cell lines.

  7. The newly identified miR (show MLXIP Antibodies)-195-RPS6KB1 axis partially illustrates the molecular mechanism of prostate cancer progression and represents a novel potential therapeutic target for prostate cancer treatment.

  8. eIF3 (show EIF3A Antibodies) has a role in controlling cell size independently of S6K1-activity

  9. MiR (show MLXIP Antibodies)-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR (show FRAP1 Antibodies)/P70S6K1.

  10. This study report that protein levels of the p70 S6 kinase (show PRKACB Antibodies) was increased in Progressive Supranuclear Palsy and Corticobasal Degeneration brains.

Cow (Bovine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 Antibodies), mTOR (show FRAP1 Antibodies), p70S6K, and ERK1/2 (show MAPK1/3 Antibodies).

  2. Lys (show LYZ Antibodies), His, and Thr (show TRH Antibodies) inhibited S6K1 phosphorylation in bovine mammary cells

Pig (Porcine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. This study found that, early in rotavirus enteritis, arginine has no impact on diarrhea but augments intestinal protein synthesis in part by p70(S6k) stimulation.

  2. There was no correlation of infarct size with expression or phosphorylation of p70S6K or GSK3beta (show GSK3b Antibodies) in ischemic postconditioning.

Mouse (Murine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1)-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 Antibodies)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 Antibodies)).

  2. Our study suggests that Ab25-35 induces autophagy and the PI3K/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies)/p70S6K pathway is involved in the process, which improves our understanding of the pathogenesis of Alzheimer's disease and provides an additional model for AD research

  3. Reducing S6K activity prevents accelerated axon growth induced by hyperactive mTOR (show FRAP1 Antibodies) in vivo.

  4. targeting the S6K pathway selectively modifies the progression of pulmonary fibrosis in the subpleural compartment of the lung

  5. the Akt/mTOR/p70S6K pathway was activated in IgA nephropathy, and our findings suggested that rapamycin may represent a viable option for the treatment of IgA nephropathy

  6. The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

  7. in adult cardiac myocytes 4-hydroxy-trans-2-nonenal stimulates protein synthesis by activation of mTORC1-p70S6K-RPS6 (show RPS6 Antibodies) signaling

  8. This is the first study highlighting the activation of S6K1 by palmitic acid as a common and novel mechanism by which its inhibition by oleic acid prevents endoplasmic reticulum stress, lipoapoptosis and insulin (show INS Antibodies) resistance in hepatocytes.

  9. Our findings suggest that S6K1 signaling is not a general integrator of energy homeostasis in the mediobasal hypothalamus but has distinct roles in the regulation of glucose homeostasis

  10. Rotenone induction of hydrogen peroxide inhibits mTOR (show FRAP1 Antibodies)-mediated S6K1 and 4E-BP1 (show EIF4EBP1 Antibodies)/eIF4E (show EIF4E Antibodies) pathways, resulting in caspase (show CASP3 Antibodies)-dependent and -independent apoptosis in neuronal cells.

RPS6KB1 Antigen Profile

Antigen Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Alternative names and synonyms associated with RPS6KB1

  • ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) antibody
  • ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1) antibody
  • 70kDa antibody
  • 2610318I15Rik antibody
  • 4732464A07Rik antibody
  • AA959758 antibody
  • AI256796 antibody
  • AI314060 antibody
  • p70 S6KA antibody
  • p70(S6K)-alpha antibody
  • p70-alpha antibody
  • p70-S6K antibody
  • p70/85s6k antibody
  • p70s6k antibody
  • PS6K antibody
  • S6K antibody
  • S6K-beta-1 antibody
  • S6K1 antibody
  • STK14A antibody

Protein level used designations for RPS6KB1

p70 S6 kinase, alpha , ribosomal protein S6 kinase I , ribosomal protein S6 kinase beta-1 , serine/threonine kinase 14 alpha , serine/threonine-protein kinase 14A , 70 kDa ribosomal protein S6 kinase 1 , P70S6K1 , S6K , S6K-beta-1 , p70 S6 kinase alpha , p70(S6K)-alpha , p70-S6K 1 , p70S6K , ribosomal protein S6 kinase polypeptide 1 , G3 serine/threonine kinase , P70S6K , S6K1 , p70 S6K-alpha , p70 S6KA , p70 ribosomal S6 kinase alpha , ribosomal protein S6 kinase, 70kD, polypeptide 1 , S6 kinase , ribosomal protein S6 kinase, 70kDa, polypeptide 1

100057481 Equus caballus
6198 Homo sapiens
404181 Bos taurus
417637 Gallus gallus
480580 Canis lupus familiaris
100127158 Sus scrofa
100009260 Oryctolagus cuniculus
72508 Mus musculus
83840 Rattus norvegicus
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