Browse our anti-Myosin IC (MYO1C) Antibodies

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anti-Myosin IC Antibodies (MYO1C)
On www.antibodies-online.com are 34 Myosin IC (MYO1C) Antibodies from 10 different suppliers available. Additionally we are shipping Myosin IC Proteins (7) and many more products for this protein. A total of 44 Myosin IC products are currently listed.
Synonyms:
C80397, DDBDRAFT_0202969, DDBDRAFT_0215355, DDB_0202969, DDB_0215355, FSGS6, HuncM-IC, mm1beta, MMI-beta, MMIb, Myo1c, MYO1E, Myosin-Ic, Myr2, nm1, NMI
list all antibodies Gene Name GeneID UniProt
MYO1C 4641 O00159
MYO1C 17913 Q9WTI7
MYO1C 65261 Q63355

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Top referenced anti-Myosin IC Antibodies

  1. Human Monoclonal MYO1C Primary Antibody for WB - ABIN659126 : Obrdlik, Louvet, Kukalev, Naschekin, Kiseleva, Fahrenkrog, Percipalle: Nuclear myosin 1 is in complex with mature rRNA transcripts and associates with the nuclear pore basket. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)
    Show all 3 references for 659126

  2. Cow (Bovine) Polyclonal MYO1C Primary Antibody for WB - ABIN2786625 : Kahle, Pridalová, Spacek, Dzijak, Hozák: Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates. in Histochemistry and cell biology 2007 (PubMed)

  3. Human Polyclonal MYO1C Primary Antibody for IHC (p), WB - ABIN358975 : Crozet, el Amraoui, Blanchard, Lenoir, Ripoll, Vago, Hamel, Fizames, Levi-Acobas, Depétris, Mattei, Weil, Pujol, Petit: Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. in Genomics 1997 (PubMed)

More Antibodies against Myosin IC Interaction Partners

Human Myosin IC (MYO1C) interaction partners

  1. Cells expressing excess of MYO1C had low basal level of phosphorylated protein kinase B (show AKT1 Antibodies).

  2. Upon DNA damage, an increase in the levels of chromatin bound motor protein nuclear myosin 1 (NM1) ensues, which appears to be functionally linked to Upsilon-H2AX (show H2AFX Antibodies) signaling.

  3. The ERK (show EPHB2 Antibodies) signaling pathway thus promotes cell motility through regulation of the subcellular localization of Myo1E (show MYO1E Antibodies).

  4. Study presents structural demonstration of a cargo protein, Neph1 (show NEPH1 Antibodies), attached to Myo1c, providing novel insights into the role of Myo1c in intracellular movements of this critical slit diaphragm protein.

  5. In glioblastoma 1321 N1 cells, we recently identified Myo1c as a new interactor of SHIP2 (show INPPL1 Antibodies). SHIP2 (show INPPL1 Antibodies) localization at lamellipodia and ruffles is impaired in Myo1c depleted cells. In the absence of Myo1c, N1 cells tend to associate to form clusters.

  6. Overexpression of MYO1C is associated with gastric cancer.

  7. Coinheritance of COL4A5 (show COL4a5 Antibodies) and MYO1E (show MYO1E Antibodies) mutations accentuate the severity of kidney disease.

  8. Ablating MYO1C function causes abnormal cholesterol distribution, which has a major selective impact on the autophagy pathway

  9. Myo1c significantly increases the frequency of kinesin-1-driven microtubule-based runs that begin at actin/microtubule intersections. The actin-binding protein (show KPTN Antibodies) tropomyosin 2 (show TPM2 Antibodies) abolishes Myo1c-specific effects on both run initiation and run termination.

  10. NM1 phosphorylation by GSK3beta (show GSK3b Antibodies) blocks NM1 ubiquitination by UBR5 (show UBR5 Antibodies) and degradation by the proteasome, leads to NM1 association with the chromatin and promotes rDNA transcription activation at G1.

Mouse (Murine) Myosin IC (MYO1C) interaction partners

  1. We propose a novel genome-wide mechanism where myosin synergizes with Pol II-associated actin to link the polymerase machinery with permissive chromatin for transcription activation.

  2. Our observations demonstrate specific changes in the expression of myosin IC isoform A that are concurrent with the occurrence of prostate cancer in the TRAMP (show DPT Antibodies) mouse prostate cancer model that closely mimics clinical prostate cancer

  3. Ca(2+) binding to calmodulin induces major conformational changes in both IQ motifs and the post-IQ domain and increases flexibility of the myosin-1c tail.

  4. The v-Crk-myosin-1c interaction, which modulates membrane dynamics by regulating Rac1 activity, is crucial for cell adhesion and spreading.

  5. Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.

  6. Myo1c functions as a slow transporter rather than a tension-sensitive anchor.

  7. the novel specific NLS (show ALDH1A2 Antibodies) brings to the cell nucleus not only the "nuclear" isoform of myosin I (show MYO1A Antibodies) (NM1 protein) but also its "cytoplasmic" isoform (Myo1c protein)

  8. The data suggest that Myosin 1c is involved in the cytoskeleton dynamics and membrane protein anchoring or sorting in B lymphocytes

  9. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity

  10. The strength and attachment lifetime of single myo1c molecules as they bind beads coated with a bilayer of 2% phosphatidylinositol 4,5-bisphosphate and 98% phosphatidylcholine (show SGMS2 Antibodies), were measured.

Zebrafish Myosin IC (MYO1C) interaction partners

  1. Myo1c is necessary for podocyte morphogenesis.

Cow (Bovine) Myosin IC (MYO1C) interaction partners

  1. Vectorial transport of G-actin (show ACTB Antibodies) was shown in live migrating endothelial cells. Myo1c (an unconventional F-actin-binding motor protein (show MYO7A Antibodies)) was identified as a major G-actin (show ACTB Antibodies)-interacting protein. The cargo-binding tail domain of Myo1c interacted with G-actin (show ACTB Antibodies).

Myosin IC (MYO1C) Antigen Profile

Antigen Summary

This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Alternative names and synonyms associated with Myosin IC (MYO1C)

  • myosin IC (MYO1C) antibody
  • class I myosin (myoC) antibody
  • myosin IC (myoC) antibody
  • myosin IC (myo1c) antibody
  • myosin IC (Myo1c) antibody
  • myosin IC (myo1c-b) antibody
  • myosin IE (MYO1E) antibody
  • si:ch211-69i14.4 (si:ch211-69i14.4) antibody
  • C80397 antibody
  • DDBDRAFT_0202969 antibody
  • DDBDRAFT_0215355 antibody
  • DDB_0202969 antibody
  • DDB_0215355 antibody
  • FSGS6 antibody
  • HuncM-IC antibody
  • mm1beta antibody
  • MMI-beta antibody
  • MMIb antibody
  • Myo1c antibody
  • MYO1E antibody
  • Myosin-Ic antibody
  • Myr2 antibody
  • nm1 antibody
  • NMI antibody

Protein level used designations for anti-Myosin IC (MYO1C) Antibodies

myosin IC , nuclear myosin 1 , myosin-Ic-like , myosin I beta , myosin-I beta , myosin-Ic , nuclear myosin I , unconventional myosin-Ic , MMI-beta , myosin-Ibeta , nuclear myosin I beta , MMIb , myosin IC-like , myosin heavy chain myr 2 , unconventional myosin Myr2 I heavy chain , MYO1E variant protein , myosin-IC , unconventional myosin 1E , unconventional myosin-Ie , Myosin I beta

GENE ID SPECIES
480646 Canis lupus familiaris
721217 Macaca mulatta
750403 Pan troglodytes
8620597 Dictyostelium discoideum AX4
10499541 Dictyostelium purpureum
100017174 Monodelphis domestica
100380193 Xenopus (Silurana) tropicalis
100452038 Pongo abelii
100484346 Ailuropoda melanoleuca
100622921 Sus scrofa
4641 Homo sapiens
17913 Mus musculus
65261 Rattus norvegicus
566459 Danio rerio
398527 Xenopus laevis
417555 Gallus gallus
281937 Bos taurus
4643 Homo sapiens
567536 Danio rerio
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