Browse our BCL2L10 Proteins (BCL2L10)

Full name:
BCL2-Like 10 (Apoptosis Facilitator) Proteins (BCL2L10)
On www.antibodies-online.com are 6 BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) Proteins from 3 different suppliers available. Additionally we are shipping BCL2L10 Antibodies (61) and many more products for this protein. A total of 71 BCL2L10 products are currently listed.
Synonyms:
AA420380, AU023065, BCL-B, Boo, C85687, Diva
list all proteins Gene Name GeneID UniProt
BCL2L10 12049 Q9Z0F3
BCL2L10 10017 Q9HD36
Rat BCL2L10 BCL2L10 114552 Q99M66

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BCL2L10 Proteins (BCL2L10) by Origin

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Top referenced BCL2L10 Proteins

  1. Human BCL2L10 Protein expressed in Escherichia coli (E. coli) - ABIN1098488 : Kang, Lee, Han, Yoon, Won, Yeom, Seong, Ko, Lee, Lee, Bae: NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling. in Biochemical and biophysical research communications 2007 (PubMed)
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More Proteins for BCL2L10 Interaction Partners

Mouse (Murine) BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) interaction partners

  1. role for Bcl-B in B cell proliferation and plasmocyte differentiation through its ability to impair B cell death and drive multiple myeloma progression.

  2. Bcl2l10, Tpx2 (show DAZL Proteins), and Aurka (show AURKA Proteins) co-localized on the meiotic spindles, and Bcl2l10 was present in the same complex with Tpx2 (show DAZL Proteins).

  3. Protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 (show BCL2 Proteins) members.

  4. analysis of a novel interaction between Bcl-2 members Diva and Harakiri

  5. Structure and sequence alignment of mouse pro-survival Bcl-2 (show BCL2 Proteins) family members reveals Boo/Diva as a divergent Bcl-2 (show BCL2 Proteins) protein.

  6. The role of Bcl2l10 is strongly associated with oocyte maturation, especially at the MI-MII transition.

  7. BCL2L10 is a novel and prime candidate related to oocyte maturation, fertility, and embryo developmental competence

Human BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10) interaction partners

  1. we describe the identification of a structural genetic variant segregating with affective psychosis in a family with multiple members suffering from bipolar I disorder. Using whole-genome sequencing, we delineated the translocation breakpoints as corresponding intragenic events disrupting BCL2L10 and PNLDC1. These data warrant further consideration for BCL2L10 and PNLDC1 as novel candidates for affective psychosis.

  2. Results found that BCL2L10 was down-regulated in human hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues; its overexpression suppresses cell growth and migration of HCC (show FAM126A Proteins) cell lines. These results suggested that BCL2L10 functions as a tumor-suppressor in HCC (show FAM126A Proteins).

  3. BCLB expression was a starvation stress sensor inducing apoptosis and autophagy simultaneously in HCC (show FAM126A Proteins) cells through the adenosine monophosphate-activated protein kinase AMPK (show GRK4 Proteins)-mTOR (show FRAP1 Proteins) signaling cascade.

  4. Identification of a variant in the BCL2L10 gene as a protective factor for the development of therapy-related myeloid neoplasms and de novo myelodysplastic syndrome.

  5. polyubiquitination and proteasomal turnover dictate the expression level and anti-apoptotic capacity of Bcl-B

  6. Data suggest that BCL2L10 is localized predominantly to mitochondria in high-quality preimplantation embryos/blastocysts; in contrast, abnormal embryos/blastocysts exhibit extra-mitochondrial localization (cytoplasm/cell nucleus) of BCL2L10.

  7. Bcl-B in complex with the BH3 motif of Bim (show BCL2L11 Proteins) protected cells from Bax (show BAX Proteins)-dependent apoptotic pathways.

  8. Bcl-B interacts with the BH3 domain of BECN1 (show BECN1 Proteins) and Bcl-B overexpression reduces autophagy triggered by a variety of pro-autophagic stimuli.

  9. Ubqln stabilizes BCLb protein, while also promoting monoubiquitination on multiple lysine residues and relocation to the cytosol.

  10. BCL2L10 methylation is associated with myelodysplastic syndromes.

BCL2L10 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Alternative names and synonyms associated with BCL2L10

  • Bcl2-like 10 (Bcl2l10)
  • BCL2-like 10 (apoptosis facilitator) (BCL2L10)
  • BCL2-like 10 (apoptosis facilitator) (Bcl2l10)
  • AA420380 protein
  • AU023065 protein
  • BCL-B protein
  • Boo protein
  • C85687 protein
  • Diva protein

Protein level used designations for BCL2L10

anti-apoptotic protein Boo , apoptosis regulator Bcl-B , bcl-2 homolog Diva , bcl-2-like protein 10 , bcl2-L-10 , anti-apoptotic protein NrH

GENE ID SPECIES
12049 Mus musculus
10017 Homo sapiens
523056 Bos taurus
114552 Rattus norvegicus
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