Browse our SOX7 Proteins (SOX7)

On are 6 SRY (Sex Determining Region Y)-Box 7 (SOX7) Proteins from 4 different suppliers available. Additionally we are shipping SOX7 Antibodies (54) and SOX7 Kits (1) and many more products for this protein. A total of 69 SOX7 products are currently listed.
sox7-A, xSox7
list all proteins Gene Name GeneID UniProt
SOX7 83595 Q9BT81
Rat SOX7 SOX7 290317  
SOX7 20680 P40646

SOX7 Proteins (SOX7) by Origin

More Proteins for SOX7 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. Overexpression of miR (show MLXIP Proteins)-935 inhibited SOX7 expression.

  2. The results suggest that miR (show MLXIP Proteins)-664 functions as an oncogene (show RAB1A Proteins) miRNA and has an important role in promoting human osteosarcoma cell invasion and migration by suppressing SOX7 expression.

  3. miR (show MLXIP Proteins)-595 played a critical role in carcinogenesis by suppression of SOX7.

  4. Aberrant methylation of the promoter regions of the SOX7 gene in patients with acute myeloid leukemias.

  5. miR (show MLXIP Proteins)-935 contributed to cell proliferation of gastric cancer through targeting SOX7.

  6. the HMG (show SSRP1 Proteins)-box is a key domain of SOX7 for negatively regulating the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway when functioning as a tumor suppressor in a glioma.

  7. The results provided unequivocal evidence for a novel tumor suppressor role of SOX7 in acute myeloid leukemia (show BCL11A Proteins)

  8. SOX7 plays an important inhibitory role in hepatocarcinogenesis, and might be a novel target for hepatocellular carcinoma therapy.

  9. Ectopic expression of miR (show MLXIP Proteins)-492 led to downregulation of SOX7 protein.

  10. Low SOX7 expression is associated with hepatocellular carcinoma.

Xenopus laevis SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. SOX7 mRNA is localized to the vegetal region of the blastula-stage embryo

  2. SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus.

  3. Vegetal pole localized Sox7 positively regulates Nodal (Xnr4, Xnr5, and Xnr6) expression, as well as the expression of genes involved in mesodermal (Xmenf, Slug, and Snail) and endodermal (Endodermin and Sox17beta) differentiation.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. SOX7 inhibits the expression of RUNX1 (show RUNX1 Proteins) target genes in hemogenic endothelium, while having no effect on RUNX1 (show RUNX1 Proteins) expression itself. SOX7 directly interacts with RUNX1 (show RUNX1 Proteins) and inhibits its transcriptional activity.

  2. Dynamically and epigenetically coordinated GATA2 (show GATA2 Proteins)/ETS1SOX7 transcription factor expression is indispensable for endothelial cell differentiation.

  3. combined deletion of Sox7, Sox17 (show SOX17 Proteins), and Sox18 (show SOX18 Proteins) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 (show SOX17 Proteins) allele largely restores arterial identity

  4. These data indicate that Sox7 is dispensable for both differentiation and maturation of primitive endoderm in an mouse embryonic stem cell model system.

  5. ETV2 (show ETV2 Proteins) directly regulates Sox7, and ETV2 (show ETV2 Proteins) governs endothelial development by regulating transcriptional networks which include Sox7.

  6. Notch and SoxF factors combinatorially regulate Dll4 expression in arteries downstream of VEGF.

  7. Haploinsufficiency of Sox7 or Gata4 (show GATA4 Proteins) is sufficient to produce anterior congenital diaphragmatic hernia in mice.

  8. SOX7 regulates the expression of VE-cadherin (show CDH5 Proteins) in the haemogenic endothelium at the onset of haematopoietic development.

  9. Sox7-sustained expression in the earliest committed hematopoietic precursors promotes the maintenance of their multipotent and self-renewing status.

  10. SOX7 and GATA-4 (show GATA4 Proteins) are competitive activators of Fgf-3 (show FGF3 Proteins) transcription

Zebrafish SRY (Sex Determining Region Y)-Box 7 (SOX7) interaction partners

  1. Sox7 levels are crucial in arterial specification in conjunction with hey2 (show HEY2 Proteins) and efnb2 (show EFNB2 Proteins) function, with mutants in all three genes displaying shunt formation and an arterial block.

  2. Sox7/18 factors and Notch (show NOTCH1 Proteins) regulate nr2f2 (show NR2F2 Proteins) gene expression during venous differentiation in zebrafish.

  3. Sox7 and Sox18 (show SOX18 Proteins)-mediated transcriptional regulation of Robo4 (show ROBO4 Proteins) is important in the developing embryonic vasculature

  4. Sox7 and sox18 (show SOX18 Proteins) are specifically expressed in the developing vasculature, and simultaneous loss of their function results in a severe loss of the arterial identity of the presumptive aorta.

  5. Sox7 and sox18 (show SOX18 Proteins) play redundant but collectively essential roles in the establishment of proper arteriovenous identity in zebrafish.

  6. Sox7 and Sox18 (show SOX18 Proteins) control arterial-venous identity by regulating Gridlock (show HEY2 Proteins) expression.

SOX7 Protein Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.

Alternative names and synonyms associated with SOX7

  • SRY (sex determining region Y)-box 7 (SOX7)
  • SRY (sex determining region Y)-box 7 (Sox7)
  • SRY (sex determining region Y)-box 7 (sox7)
  • SRY-box containing gene 7 (Sox7)
  • SRY-box containing gene 7 (sox7)
  • sox7-A protein
  • xSox7 protein

Protein level used designations for SOX7

transcription factor SOX-7 , SRY-box containing gene 7 , SRY (sex determining region Y)-box 7, xSox7 protein , transcription factor Sox-7 , mSOX7 , SRY (sex determining region Y)-box 7

83595 Homo sapiens
290317 Rattus norvegicus
378665 Xenopus laevis
771337 Gallus gallus
486084 Canis lupus familiaris
541256 Bos taurus
100155811 Sus scrofa
20680 Mus musculus
394203 Danio rerio
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