Browse our CAPN10 Proteins (CAPN10)

Full name:
Calpain 10 Proteins (CAPN10)
On www.antibodies-online.com are 5 Calpain 10 (CAPN10) Proteins from 4 different suppliers available. Additionally we are shipping CAPN10 Antibodies (30) and CAPN10 Kits (5) and many more products for this protein. A total of 45 CAPN10 products are currently listed.
Synonyms:
AW049679, CANP10, Capn8, CAPN10, mKIAA1845, NIDDM1
list all proteins Gene Name GeneID UniProt
CAPN10 11132 Q9HC96
CAPN10 23830 Q9ESK3
CAPN10 63834 Q9ES66

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CAPN10 Proteins (CAPN10) by Origin

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Human Calpain 10 (CAPN10) interaction partners

  1. association between SNP 63 of CAPN10 and gestational diabetes mellitus is only significant in the heterozygous model

  2. There were significant differences between the type 2 diabetes mellitus patients and controls in the risk allele distributions of rs3792267 (CAPN10) (P = 0.002), rs1501299 (APM1 (show ZBTB7C Proteins)) (P = 0.017), and rs3760776 (FUT6 (show FUT6 Proteins)) (P = 0.031).

  3. The study results were suggestive of a positive association between Gly972Arg of IRS1 (show IRS1 Proteins) and PCOS in the south Indian population, while INS (show INS Proteins), IRS2 (show IRS2 Proteins), PPAR-G (show ARF6 Proteins) and CAPN10 failed to show any association with PCOS in our studied population.

  4. These findings indicate that the Calpain-10 SNP 43 may be related to obstructive sleep apnea/hypopnea syndrome with ischemic stroke, with SNP 43 GG genotype as a risk factor for obstructive sleep apnea/hypopnea with ischemic stroke

  5. Subjects with the GG genotype of the rs2975762 variant of the CAPN10 gene were better responders to dietary intervention, showing increased HDL (show HSD11B1 Proteins)-C concentrations from the first month of treatment

  6. due to its association with androgen excess in phenotype A, CAPN 10 gene polymorphism UCSNP-43 could be used as a genetic marker for CVD in young PCOS women.

  7. genetic association studies in Asian populations: Data suggest that an SNP in CAPN10 (SNP43 G>A, rs3792267) is associated with type 2 diabetes in Asian populations, especially in Chinese populations. [META-ANALYSIS]

  8. SNP-63 and indel-19 variant of the CAPN10 gene do not represent a risk factor for polycystic ovary syndrome in Mexican women of reproductive age.

  9. Data indicate no association between calpain 10 (CAPN10) polymorphisms and type 2 diabetes mellitus.

  10. 121 haplotype and 122/121 haplotype combination of SNP-19, -44 and -63 in the Calpain-10 gene are associated with the development of type 2 diabetes in Turkish patients.

Mouse (Murine) Calpain 10 (CAPN10) interaction partners

  1. Capn10 plays an important role in regulating obesity and diabetes in mice.

  2. calpain-derived Htt (show HTT Proteins) fragmentation has a role in Huntington's disease and aberrant activation of calpains may play a role in HD pathogenesis

  3. calpain-10 has a role in beta-cell survival and is suppressed by RyR2

  4. These results provide evidence that several previously postulated splice variants of calpain 10 are localized to the mitochondria in kidneys of rabbits, rats, and mice.

  5. Calpain 10 levels specifically decrease in kidney tissues when renal function decreases.

CAPN10 Protein Profile

Protein Summary

Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation\; domain II, the protease domain\; domain III, a linker domain of unknown function\; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

Alternative names and synonyms associated with CAPN10

  • calpain 10 (CAPN10)
  • calpain 10 (capn10)
  • calpain 10 (Capn10)
  • AW049679 protein
  • CANP10 protein
  • Capn8 protein
  • CAPN10 protein
  • mKIAA1845 protein
  • NIDDM1 protein

Protein level used designations for Calpain 10 Proteins (CAPN10)

calpain 10 , calpain-10-like , calcium-activated neutral proteinase 10 , calpain-10 , calpain-like protease CAPN10 , CANP 10 , calpain 8

GENE ID SPECIES
424945 Gallus gallus
607311 Canis lupus familiaris
724069 Sus scrofa
733407 Xenopus laevis
789674 Bos taurus
100379827 Xenopus (Silurana) tropicalis
100389664 Callithrix jacchus
100478594 Ailuropoda melanoleuca
100022544 Monodelphis domestica
100603845 Nomascus leucogenys
11132 Homo sapiens
23830 Mus musculus
63834 Rattus norvegicus
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