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Browse our Glutamate Dehydrogenase 1 Proteins (GLUD1)

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Glutamate Dehydrogenase 1 Proteins (GLUD1)
On are 9 Glutamate Dehydrogenase 1 (GLUD1) Proteins from 5 different suppliers available. Additionally we are shipping Glutamate Dehydrogenase 1 Antibodies (64) and Glutamate Dehydrogenase 1 Kits (43) and many more products for this protein. A total of 121 Glutamate Dehydrogenase 1 products are currently listed.
Ac2-281, AI118167, cb719, CORTRD1, G6PDH, GDH, Gdh-X, Gdh1, GDH 1, Glud, glud1, Gludeha, Gludl, GLUTAMATE DECARBOXYLASE 1, glutamate dehydrogenase 1, MRG-2, MRG7.13, MRG7_13, wu:fb16e02, wu:fb58f12, wu:fe37f03, wu:fj43f02, zgc:55630, zgc:192851
list all proteins Gene Name GeneID UniProt
GLUD1 2746 P00367
GLUD1 14661 P26443
GLUD1 24399 P10860

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Glutamate Dehydrogenase 1 Proteins (GLUD1) by Origin

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More Proteins for Glutamate Dehydrogenase 1 Interaction Partners

Soybean (Glycine max) Glutamate Dehydrogenase 1 (GLUD1) interaction partners

  1. Characterized cDNA clones of sequences GDH1 and GDH2 (show GLUD2 Proteins) that code for putative alpha- and beta-subunits of the NADH dependent enzyme. Although the gene transcripts are co-localized in roots of etiolated seedlings, the ratio of the two subunits varies among tissues.

Cow (Bovine) Glutamate Dehydrogenase 1 (GLUD1) interaction partners

  1. near-atomic resolution cryoelectron microscopy structures, at resolutions ranging from 3.2 A to 3.6 A for GDH complexes, is reported.

  2. Data show that glutamate (show GRIN2A Proteins) dehydrogenase activity in an enzymatic catalyzed reaction by tracing the increasing of oxidation current of NADH.

  3. Data show that heat inactivation of the native GDH enzyme occurred with a rate constant of inactivation of 0.252 min-1 (show CD59 Proteins).

  4. the existence of two partially unfolded states of GDH at moderate acidic pHs (show PCBD1 Proteins) which may be considered as molten and pre-molten globule-like states.

Human Glutamate Dehydrogenase 1 (GLUD1) interaction partners

  1. Hypoxia-induced expression of GDH relies on the up-regulation of HIF1alpha (show HIF1A Proteins) but not HIF2alpha (show EPAS1 Proteins). HIF1alpha (show HIF1A Proteins) binds the promoter of GDH and promotes the transcription of GDH gene in lung cancer cells.

  2. Results indicate that it is possible to use high-throughput screening methods to find activators for glutamate (show GRIN1 Proteins) dehydrogenase (GDH) that might be useful as pharmaceutical agents.

  3. cortisol reduces glucose-6-phosphate (G6P) flux through H6PDH by increasing luminal NADPH (show NQO1 Proteins), thereby allowing more G6P for hydrolysis via G6Pase (show G6PC Proteins)

  4. Missense mutation of GLUD1 is associated with Hyperinsulinism-hyperammonemia syndrome.

  5. GLUD1 is differentially expressed in the cellular and subcellular compartments of numerous tissues.

  6. GLUD1 mutation is associated with congenital hyperinsulinism-hyperammonemia.

  7. Inhibition of glucose-6-phosphate dehydrogenase (show G6PD Proteins) sensitizes cisplatin-resistant cells to death.

  8. Study of the expression of the GDH1/2 in human steroidogenic organs revealed that, while GDH2 (show GLUD2 Proteins) was expressed specifically in steroid-synthesizing cells, GDH1 was expressed both in the cells that produce steroids and in those that lack endocrine function.

  9. The G allele of rs6688832 in H6PD might exert potential genetic protective role against the development of PCOS, especially in overweight women. PCOS patients with AG genotype of rs6688832 might confer risk to the phenotype of hyperandrogenemia of PCOS.

  10. GDH plays a critical role in colorectal cancer progression

Mouse (Murine) Glutamate Dehydrogenase 1 (GLUD1) interaction partners

  1. lack of glutamate (show GRIN1 Proteins) oxidation in brain-specific (show CALY Proteins) GDH (show UGDH Proteins) null CnsGlud1-/- mice resulted in a central energy-deprivation state with increased ADP/ATP ratios and phospho-AMPK (show PRKAA1 Proteins) in the hypothalamus.

  2. This study demonstrated a critical requirement for GluD1 in normal spine development in the cortex and hippocampus.

  3. The GDH (show UGDH Proteins) activity in mice is highest in the liver with NAD(+) as a coenzyme and highest GDH (show UGDH Proteins) activity was determined at a glutamate (show GRIN1 Proteins) concentration of 10 mM.

  4. Age-related increases of glutamate (show GRIN1 Proteins) were observed only in the striatum of the glutamate dehydrogenase 1 mice

  5. Glutamate (show GRIN1 Proteins) hyperactivity caused gene expression changes in the hippocampus at all ages

  6. GluD1 regulates the connectivity of parallel fiber-interneuron synapses and promotes differentiation of interneurons.

  7. The GDH1 is a key metabolic enzyme with emerging roles in insulin (show INS Proteins) regulation. MitoNEET (show CISD1 Proteins) forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator.

  8. GluD1 is crucial for normal functioning of synapses and absence of GluD1 leads to specific abnormalities in learning and memory.

  9. Permissive levels of glutamate (show GRIN1 Proteins) are required for the full development of glucose-stimulated insulin (show INS Proteins) secretion and glutamate (show GRIN1 Proteins) dehydrogenase plays an indispensable role in this process.

  10. Mice deficient in Glud1 exhibit deficient oxidative catabolism of glutamate (show GRIN1 Proteins) in astrocytes, showing that GDH (show UGDH Proteins) is required for Krebs cycle pathway; however, lack of GDH (show UGDH Proteins) modifies metabolic handling of glutamate (show GRIN1 Proteins) without altering synaptic transmission.

Arabidopsis thaliana Glutamate Dehydrogenase 1 (GLUD1) interaction partners

  1. the carboxyl terminus of the GDH (show UGDH Proteins) subunit is involved in the stabilization of the oligomeric structure of the enzyme.

  2. In leaves and stems of arabidopsis and tobacco, both the alpha- and beta-subunits of Glutamate (show GRIN2A Proteins) dehydrogenase are targeted to the mitochondria of the companion cells.

Glutamate Dehydrogenase 1 (GLUD1) Protein Profile

Protein Summary

There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.

Alternative names and synonyms associated with Glutamate Dehydrogenase 1 (GLUD1)

  • glutamate dehydrogenase 1 (GLUD1)
  • glutamate dehydrogenase 1 (glud1)
  • glutamate dehydrogenase 1 (gdh1)
  • glutamate dehydrogenase 1 (HacjB3_00300)
  • glutamate dehydrogenase 1 (gdh01)
  • glutamate dehydrogenase 1 (Glud1)
  • glutamate dehydrogenase 1 (GDH1)
  • glutamate dehydrogenase 1-like (LOC100351029)
  • glutamate dehydrogenase 1b (glud1b)
  • hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (H6PD)
  • Ac2-281 protein
  • AI118167 protein
  • cb719 protein
  • CORTRD1 protein
  • G6PDH protein
  • GDH protein
  • Gdh-X protein
  • Gdh1 protein
  • GDH 1 protein
  • Glud protein
  • glud1 protein
  • Gludeha protein
  • Gludl protein
  • glutamate dehydrogenase 1 protein
  • MRG-2 protein
  • MRG7.13 protein
  • MRG7_13 protein
  • wu:fb16e02 protein
  • wu:fb58f12 protein
  • wu:fe37f03 protein
  • wu:fj43f02 protein
  • zgc:55630 protein
  • zgc:192851 protein

Protein level used designations for GLUD1

mitochondrial glutamate dehydrogenase 1 , glutamate dehydrogenase 1 , glutamate dehydrogenase 1, mitochondrial-like , GDH 1 , glutamate dehydrogenase 1, mitochondrial , glutamate dehydrogenase (NAD(P)+) , memory-related gene 2 protein , 6-phosphogluconolactonase , G6PD, H form , GDH/6PGL endoplasmic bifunctional protein , glucose 1- dehydrogenase , glucose dehydrogenase , glucose dehyrogenase , glucose-6-phosphate dehydrogenase, salivary

450576 Pan troglodytes
483859 Canis lupus familiaris
496554 Xenopus (Silurana) tropicalis
547687 Glycine max
693461 Macaca mulatta
100135453 Ovis aries
9417853 Halalkalicoccus jeotgali B3
100020220 Monodelphis domestica
100379123 Oncorhynchus mykiss
100443755 Pongo abelii
100587725 Nomascus leucogenys
281785 Bos taurus
2746 Homo sapiens
446858 Xenopus laevis
423612 Gallus gallus
14661 Mus musculus
24399 Rattus norvegicus
100684847 Canis lupus familiaris
100722523 Cavia porcellus
100157162 Sus scrofa
831935 Arabidopsis thaliana
100351029 Oryctolagus cuniculus
373092 Danio rerio
9563 Homo sapiens
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