Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
The present study identified USP7 (show USP7 ELISA Kits) and TDP-43 as the regulators of CRY1 (show CRY1 ELISA Kits) and CRY2 (show CRY2 ELISA Kits), underscoring the significance of the stability control process of CRY (show CRY2 ELISA Kits) proteins for period determination in the mammalian circadian clockwork.
The data indicated that TDP-43/p35 (show ANXA1 ELISA Kits) contributed to stress granule formation by promoting RACK1 (show GNB2L1 ELISA Kits) expression. The study sheds new light on post-transcriptional regulation and apoptosis in osteoarthritis (OA) by RACK1 (show GNB2L1 ELISA Kits), which is a potential treatment strategy for OA.
Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation.
This study demonstrated that single nucleotide TDP-43 mutation within a Taiwanese family.
Molecular analysis of pathological TDP-43 aggregates in amyotrophic lateral sclerosis brains.
All patients with behavioural variant Frontotemporal dementia + motor neurone disease (MND (show CLN8 ELISA Kits)) or MND (show CLN8 ELISA Kits) showed plentiful p62 (show GTF2H1 ELISA Kits)/TDP-43 positive inclusions in remaining anterior horn cells
TDP-43 within neurons plays an essential role of mRNA transport into distal neurites for local translation, and thus, dysfunctions of TDP-43 cause neural diseases such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
a combination of TDP-43 and an motor neuron degeneration factors can be used to reflect abnormal RNA metabolism in WBCs and thus be useful as ALS-onset biomarkers.
both phosphorylated and calpain-cleaved TDP-43 fragments persist intracellularly for a length of time that is sufficient for self-aggregation, thereby serving as seeds for inclusions.
misfolded TDP-43 is cleared by VHL (show VHL ELISA Kits)/CUL2 (show CUL2 ELISA Kits) in a step-wise manner via fragmentation.
TDP-43 functions within a network of hnRNP (show HNRNPH2 ELISA Kits) proteins to inhibit the production of a truncated human SORT1 (show SORT1 ELISA Kits) receptor.
Data demonstrate the existence of a physiological decrease of TDP-43/TBPH levels with aging in brain tissue both in wild-type mice and flies, showing that it is an evolutionary conserved phenomenon
This study demonistrated that proprioceptive nerve endings in muscles revealed early and alterations at Ia/II proprioceptive nerve endings in muscle spindles and in the absence of alterations in alpha-motor axons in TDP43(A315T) transgenic mice.
UBQLN2 (show UBQLN2 ELISA Kits) dysregulation in neurons can drive NF-kappaB (show NFKB1 ELISA Kits) activation and cytosolic TDP-43 aggregation.
These findings demonstrate a role for PABPN1 (show PABPN1 ELISA Kits) in rescuing several cytopathological features of TDP-43 proteinopathy by increasing the turnover of pathologic proteins.
identifies DDX58 (show DDX58 ELISA Kits) and MTHFSD as two TDP-43 targets that are misregulated in amyotrophic lateral sclerosis. 1
Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.
we observed a glial reaction and an activity-dependent modification of Shh (show SHH ELISA Kits), Noggin (show NOG ELISA Kits), and Numb (show NUMB ELISA Kits) proteins. we found that Shh (show SHH ELISA Kits) and Noggin (show NOG ELISA Kits) could affect motor performance and that these proteins could be associated with both TDP-43 and Numb (show NUMB ELISA Kits)
The ability of TDP-43 to promote CD14 (show CD14 ELISA Kits)-mediated activation of microglial NF-kappaB (show NFKB1 ELISA Kits) and AP-1 (show JUN ELISA Kits) pathways, as well as the NLRP3 (show NLRP3 ELISA Kits) inflammasome.
Data indicate a method for site-directed single nucleotide editing in two disease-related genes, DNA binding protein (show CNBP ELISA Kits) tardbp and RNA binding protein fus (show FUS ELISA Kits).
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.
TARDBP and FUS (show FUS ELISA Kits) act in a pathogenic pathway that is independent of SOD1 (show SOD1 ELISA Kits).
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
TAR DNA binding protein
, TAR DNA-binding protein 43
, Tardbp protein
, TAR DNA-binding protein-43