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Browse our BAI1-Associated Protein 2-Like-1 Proteins (BAIAP2L1)

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BAI1-Associated Protein 2-Like-1 Proteins (BAIAP2L1)
On are 6 BAI1-Associated Protein 2-Like-1 (BAIAP2L1) Proteins from 4 different suppliers available. Additionally we are shipping BAI1-Associated Protein 2-Like-1 Antibodies (40) and BAI1-Associated Protein 2-Like-1 Kits (3) and many more products for this protein. A total of 53 BAI1-Associated Protein 2-Like-1 products are currently listed.
1300006M19Rik, AI585895, BAIAP2L1, cb1023, IRTKS, MGC131079, RGD1308452, zgc:85624
list all proteins Gene Name GeneID UniProt
BAIAP2L1 55971 Q9UHR4
BAIAP2L1 66898 Q9DBJ3
BAIAP2L1 304282 Q3KR97

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BAI1-Associated Protein 2-Like-1 Proteins (BAIAP2L1) by Origin

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More Proteins for BAI1-Associated Protein 2-Like-1 Interaction Partners

Human BAI1-Associated Protein 2-Like-1 (BAIAP2L1) interaction partners

  1. Upregulation of BAIAP2L1 is associated with ovarian cancer.

  2. Lacking the Bin-Amphiphysin (show AMPH Proteins)-Rvs (BAR) dimerization domain of BAIAP2L1.

  3. IRTKS can interact with epidermal growth factor receptor (EGFR (show EGFR Proteins)), results in the phosphorylation of extracellular signal-regulated kinase

  4. Identification of a novel oncogenic FGFR3 (show FGFR3 Proteins)-BAIAP2L1 fusion protein in bladder cancer.

  5. These data suggest that IRTKS is a novel regulator of p53 (show TP53 Proteins), modulating low level of MDM2 (show MDM2 Proteins)-mediated p53 (show TP53 Proteins) ubiquitination in unstressed cells.

  6. data suggest Src (show SRC Proteins)-stimulated IRTKS phosphorylation is essential for its function in cell motility

  7. Results describe the NMR structure of insulin receptor tyrosine kinase substrate (IRTKS) SH3 domain in complex with a repeat from Escherichia coli-secreted protein F-like protein encoded on prophage U (EspF(U)).

  8. Study characterised IRTKS, which has widespread tissue distribution, is a substrate for the insulin receptor and binds Rac, and expression of IRTKS induces clusters of short actin bundles rather than filopodia-like protrusions.

  9. Screening of the mammalian SH3 proteome for the ability to bind EspF(U) identified the SH3 domain of insulin receptor tyrosine kinase substrate (IRTKS), a factor known to regulate the cytoskeleton.

Mouse (Murine) BAI1-Associated Protein 2-Like-1 (BAIAP2L1) interaction partners

  1. The IRTKS, as an adaptor of the insulin receptor (IR (show INSR Proteins)), modulates IR-IRS1 (show IRS1 Proteins)-PI3K-AKT (show AKT1 Proteins) signaling via regulating the phosphorylation of IR.

  2. IRTKS functions as a negative modulator of excessive inflammation in viral infections.

BAI1-Associated Protein 2-Like-1 (BAIAP2L1) Protein Profile

Protein Summary

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Alternative names and synonyms associated with BAI1-Associated Protein 2-Like-1 (BAIAP2L1)

  • BAI1-associated protein 2-like 1a (baiap2l1a)
  • BAI1-associated protein 2-like 1 (BAIAP2L1)
  • BAI1-associated protein 2-like 1 (baiap2l1)
  • BAI1-associated protein 2-like 1 (LOC100224219)
  • BAI1-associated protein 2-like 1 (Baiap2l1)
  • 1300006M19Rik protein
  • AI585895 protein
  • BAIAP2L1 protein
  • cb1023 protein
  • IRTKS protein
  • MGC131079 protein
  • RGD1308452 protein
  • zgc:85624 protein

Protein level used designations for BAIAP2L1

BAI1-associated protein 2-like 1 , insulin receptor tyrosine kinase substrate homolog , insulin receptor tyrosine kinase substrate , brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1-like , BAI1-associated protein 2-like protein 1 , brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

387261 Danio rerio
416437 Gallus gallus
463559 Pan troglodytes
479748 Canis lupus familiaris
734941 Xenopus laevis
100224219 Taeniopygia guttata
100400471 Callithrix jacchus
55971 Homo sapiens
66898 Mus musculus
304282 Rattus norvegicus
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